Trans-10,cis-12 CLA increases liver and decreases adipose tissue lipids in mice: Possible roles of specific lipid metabolism genes

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Lipids

• Publication date

  2003-05-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s11745-003-1090-0PMID 12880104
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Dietary conjugated linoleic acid in health: physiological effects and mechanisms of action.

  2002influential reference
• Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin

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• Conjugated linoleic acid supplementation in humans: Effects on circulating leptin concentrations and appetite

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  1999cited by this paper
• Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse.

  1998cited by this paper
• Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression.

  1996cited by this paper
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