Effects of tempol, a free radical scavenger, on long-term hyperdynamic porcine bacteremia*

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Critical Care Medicine

• Publication date

  2005-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/01.CCM.0000162927.94753.63PMID 15891336
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• EFFECTS OF A MEMBRANE-PERMEABLE RADICAL SCAVENGER, TEMPOL, ON INTRAPERITONEAL SEPSIS-INDUCED ORGAN INJURY IN RATS

  2005cited by this paper
• Coagulation in sepsis

  2004influential reference
• Systemic, pulmonary, and hepatosplanchnic effects of N-acetylcysteine during long-term porcine endotoxemia*

  2004cited by this paper
• Tempol reduces the activation of nuclear factor-kappaB in acute inflammation.

  2004influential reference
• SELECTIVE INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITION DURING LONG-TERM HYPERDYNAMIC PORCINE BACTEREMIA

  2004cited by this paper
• Treatment with N-acetylcysteine plus deferoxamine protects rats against oxidative stress and improves survival in sepsis*

  2004influential reference
• Superoxide Production in the Vasculature of Lipopolysaccharide-Treated Rats and Pigs

  2003cited by this paper
• Deactivation of Norepinephrine by Peroxynitrite as a New Pathogenesis in the Hypotension of Septic Shock

  2003cited by this paper
• Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: Correlation with preserved circulating catecholamines*

  2003influential reference
• Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine.

  2003cited by this paper
• A superoxide dismutase mimetic with catalase activity (EUK-8) reduces the organ injury in endotoxic shock.

  2003cited by this paper
• Intestinal epithelial hyperpermeability: update on the pathogenesis of gut mucosal barrier dysfunction in critical illness

  2003cited by this paper
• Membrane-permeable radical scavengers (tempol) for shock, ischemia-reperfusion injury, and inflammation

  2003cited by this paper
• Oxidative stress in septic shock and disseminated intravascular coagulation.

  2002cited by this paper
• Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis

  2002influential reference
• The isoprostanes: their role as an index of oxidant stress status in human pulmonary disease.

  2002influential reference
• Association between mitochondrial dysfunction and severity and outcome of septic shock.

  2002cited by this paper
• Modification of &agr;1-adrenoceptors by peroxynitrite as a possible mechanism of systemic hypotension in sepsis*

  2002cited by this paper
• Adenosine triphosphate-magnesium dichloride during hyperdynamic porcine endotoxemia: Effects on hepatosplanchnic oxygen exchange and metabolism*

  2002cited by this paper
• Presence of nitrotyrosine with minimal inducible nitric oxide synthase induction in lipopolysaccharide-treated pigs.

  2001influential reference
• POST‐INJURY MULTIPLE ORGAN FAILURE: THE ROLE OF THE GUT

  2001cited by this paper
• von Willebrand factor antigen is an independent marker of poor outcome in patients with early acute lung injury

  2001cited by this paper
• Beneficial effects of tempol, a membrane-permeable radical scavenger, on the multiple organ failure induced by zymosan in the rat

  2001cited by this paper
• The SOD mimetic tempol restores vasodilation in afferent arterioles of experimental diabetes.

  2001cited by this paper
• Effects of selective iNOS inhibition on gut and liver O2-exchange and energy metabolism during hyperdynamic porcine endotoxemia.

  2001cited by this paper
• Nitroxide TEMPOL impairs mitochondrial function and induces apoptosis in HL60 cells

  2001cited by this paper
• Determination of isoprostaglandin F2alpha type III in human urine by gas chromatography-electronic impact mass spectrometry. Comparison with enzyme immunoassay.

  2001cited by this paper
• The effects of Tempol on ferritin synthesis and Fe metabolism in lens epithelial cells.

  2000cited by this paper
• The antioxidant paradox.

  2000cited by this paper
• Volume replacement in trauma patients within the first 24 h and its impact on the interpretation of biochemical data

  2000influential reference
• Membrane-permeable radical scavenger, tempol, reduces multiple organ injury in a rodent model of Gram-positive shock

  2000influential reference
• Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat.

  2000influential reference
• Beneficial effects of tempol, a membrane-permeable radical scavenger, in a rodent model of splanchnic artery occlusion and reperfusion.

  2000influential reference
• Expired nitric oxide and shock in higher order species.

  1999cited by this paper
• Redox imbalance in the critically ill.

  1999cited by this paper
• A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock.

  1999influential reference
• Decline in the expression of copper/zinc superoxide dismutase in the kidney of rats with endotoxic shock: Effects of the superoxide anion radical scavenger, tempol, on organ injury

  1998influential reference
• Dobutamine improves gastrointestinal mucosal blood flow in a porcine model of endotoxic shock.

  1997influential reference

• Redox Regulation of Microvascular Physiology and Pathophysiology: Insights into Therapeutic Strategies and Limitations

  2025cites this paper
• Renal arterial infusion of tempol prevents medullary hypoperfusion, hypoxia, and acute kidney injury in ovine Gram‐negative sepsis

  2023cites this paper
• Therapeutic Potential of Small Molecules Targeting Oxidative Stress in the Treatment of Chronic Obstructive Pulmonary Disease (COPD): A Comprehensive Review

  2022cites this paper
• Bioinspired copper single‐atom nanozyme as a superoxide dismutase‐like antioxidant for sepsis treatment

  2022cites this paper
• Therapeutic potential of megadose vitamin C to reverse organ dysfunction in sepsis and COVID‐19

  2021cites this paper
• Microcirculation vs. Mitochondria—What to Target?

  2020cites this paper
• Distinct Myocardial Mechanisms Underlie Cardiac Dysfunction in Endotoxemic Male and Female Mice

  2016cites this paper
• Renal Hemodynamics in AKI: In Search of New Treatment Targets.

  2016cites this paper
• Experimental treatments for mitochondrial dysfunction in sepsis: A narrative review

  2015cites this paper
• Vasoplegia in septic shock: do we really fight the right enemy?

  2014cites this paper
• Plasma and tissue levels of neuropeptide y in experimental septic shock: relation to hemodynamics, inflammation, oxidative stress, and hemofiltration.

  2011cites this paper
• UNIVERSIDADE DO EXTREMO SUL CATARINENSE - UNESC PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE - PPGCS

  2011cites this paper
• Oxidative Stress in Animal Models with Special Reference to Experimental Porcine Endotoxemia

  2011cites this paper
• Use of Free Radicals and Antioxidants in Inflammatory Processes of Animals

  2011cites this paper
• Some etiopathogenetic aspects of chronic prostatitis: mycoplasmas, coryneform bacteria and oxidative stress

  2011cites this paper
• New developments in septic acute kidney injury.

  2010cites this paper
• EDARAVONE, A NOVEL FREE RADICAL SCAVENGER, REDUCES HIGH-MOBILITY GROUP BOX 1 AND PROLONGS SURVIVAL IN A NEONATAL SEPSIS MODEL

  2009cites this paper
• The Microcirculation in Sepsis

  2009cites this paper
• COUPLED PLASMA FILTRATION ADSORPTION IN EXPERIMENTAL PERITONITIS-INDUCED SEPTIC SHOCK

  2009cites this paper
• High versus standard-volume haemofiltration in hyperdynamic porcine peritonitis: effects beyond haemodynamics?

  2009cites this paper
• Altered plasma proteome during an early phase of peritonitis-induced sepsis.

  2009cites this paper
• Effects of levosimendan and dobutamine on experimental acute lung injury in rats.

  2009cites this paper
• From Hemodynamics To Proteomics: Unraveling the Complexity of Acute Kidney Injury in Sepsis

  2008cites this paper
• Renal haemodynamic, microcirculatory, metabolic and histopathological responses to peritonitis-induced septic shock in pigs

  2008cites this paper
• Thrombosis in central catheter-associated Staphylococcus aureus bacteremia: always scan the site?

  2008cites this paper
• Pathophysiology of tissue acidosis in septic shock: blocked microcirculation or impaired cellular respiration?

  2008cites this paper
• A new long-term porcine model of fecal peritonitis-induced septic shock hemodynamics, gas exchange, metabolism, and organ function

  2008cites this paper
• Effects of a cantaloupe melon extract/wheat gliadin biopolymer during aortic cross-clamping

  2007cites this paper
• EFFECTS OF COMBINING INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITOR AND RADICAL SCAVENGER DURING PORCINE BACTEREMIA

  2007cites this paper
• Catecholamines and vasopressin during critical illness.

  2006cites this paper
• Polyethylene glycol-superoxide dismutase prevents endotoxin-induced cardiac dysfunction.

  2006cites this paper
• Can (hyperbaric) oxygen turn off the motor of multiorgan dysfunction?

  2006cites this paper
• Catecholamines and vasopressin during critical illness.

  2006cites this paper
• Perfusion pressure manipulation in porcine sepsis: effects on intestinal hemodynamics.

  2006cites this paper
• The use of medical early warning scores in high-risk acute coronary syndrome patients in a district hospital setting

  2006cites this paper
• Role of oxidative stress in experimental sepsis and multisystem organ dysfunction

  2006cites this paper
• OLEUROPEIN: A NOVEL IMMUNOMODULATOR CONFERRING PROLONGED SURVIVAL IN EXPERIMENTAL SEPSIS BY PSEUDOMONAS AERUGINOSA

  2006cites this paper
• Mechanical ventilation in ARDS: One size does not fit all.

  2005cites this paper
• Improving outcomes in septic shock--can we define causality and find more efficacious treatments?

  2005cites this paper
• Free radical scavenging as a therapeutic strategy for bacteremia.

  2005cites this paper
• Hemodynamic support in septic shock: is restoring a normal blood pressure the right target?

  2005cites this paper
• Polyethylene Glycol–superoxide Dismutase Prevents Endotoxin-induced Cardiac Dysfunction Methods Animal Protocol

  year unknowncites this paper