Mapping functional epitopes of the human LFA-1 glycoprotein: monoclonal antibody inhibition of NK and CTL effectors.

No abstract is available for this paper.

• Publication year

  1986

• Venue

  Human Immunology

• Publication date

  1986-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0198-8859(86)90280-6PMID 2432044
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• LFA-1 membrane molecule in the regulation of homotypic adhesions of human B lymphocytes.

  1985cited by this paper
• Effects of monoclonal antibodies to the a and β chains of the human lymphocyte function‐associated (H‐LFA‐1) antigen on T lymphocyte functions

  1985cited by this paper
• Defective natural killer cytotoxicity and polymorphonuclear leukocyte antibody-dependent cellular cytotoxicity in patients with LFA-1/OKM-1 deficiency.

  1984cited by this paper
• LFA-1, LFA-2, and LFA-3 antigens are involved in CTL-target conjugation.

  1984cited by this paper
• The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions.

  1983cited by this paper
• A human leukocyte differentiation antigen family with distinct alpha- subunits and a common beta-subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule

  1983cited by this paper
• Human lymphocyte function associated antigen-1 (LFA-1): identification of multiple antigenic epitopes and their relationship to CTL-mediated cytotoxicity.

  1983cited by this paper
• Inhibition of phagocytosis of complement C3- or immunoglobulin G-coated particles and of C3bi binding by monoclonal antibodies to a monocyte-granulocyte membrane glycoprotein (Mol).

  1983cited by this paper
• Blockade of NK cell lysis is a property of monoclonal antibodies that bind to distinct regions of T-200.

  1983cited by this paper
• Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.

  1982cited by this paper
• Selective blockade of human natural killer cells by a monoclonal antibody.

  1982cited by this paper
• Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor

  1982cited by this paper
• Effects of a cloned cell line with NK activity on bone marrow transplants, tumour development and metastasis in vivo

  1982cited by this paper
• Definitive evidence that natural killer (NK) cells inhibit experimental tumor metastases in vivo.

  1981cited by this paper
• Evidence for T cell nature and heterogeneity within natural killer (NK) and antibody-dependent cellular cytotoxicity (ADCC) effectors: a comparison with cytolytic T lymphocytes (CTL).

  1981cited by this paper
• Phenotypes of human natural killer cell populations detected with monoclonal antibodies.

  1981cited by this paper
• Determination of surface antigens on highly purified human NK cells by flow cytometry with monoclonal antibodies.

  1981cited by this paper
• Properties and usefulness of the original K-562 human myelogenous leukemia cell line.

  1979cited by this paper
• Role of non-conventional natural killer cells in resistance against syngeneic tumour cells in vivo

  1977cited by this paper
• Natural cytotoxic reactivity of human lymphocytes against a myeloid cell line: characterization of effector cells.

  1977cited by this paper

• In contrast to anti-tumor activity, YT cell and primary NK cell cytotoxicity for Cryptococcus neoformans bypasses LFA-1.

  2009cites this paper
• Biology of Natural Killer Cells

  2008cites this paper
• Structural Mapping of Immunoglobulin Subclasses Using Multiplexed Bead Flow Cytometry

  2006cites this paper
• Loss of B 7 . 2 ( CD 86 ) and Intracellular Adhesion Molecule 1 ( CD 54 ) Expression Is Associated with Decreased Tumor-infiltrating T Lymphocytes in Diffuse B-cell Large-cell Lymphoma 1

  2000cites this paper
• IMMUNOLOGICAL ALTERATIONS IN PATIENTS WITH PRIMARY TUMORS IN CENTRAL NERVOUS SYSTEM

  2000cites this paper
• Ligation of ICAM-1 molecules inhibits target cell-induced granule exocytosis of IL-12-activated natural killer cells.

  2000cites this paper
• Loss of B7.2 (CD86) and intracellular adhesion molecule 1 (CD54) expression is associated with decreased tumor-infiltrating T lymphocytes in diffuse B-cell large-cell lymphoma.

  2000cites this paper
• Impairment of natural killer cell activity in Chlamydia trachomatis infected individuals

  1999cites this paper
• Immunological alterations in patients with primary tumors in central nervous system.

  1999cites this paper
• Leukocyte function-associated antigen-1 expression on decidual natural killer cells in patients with early pregnancy loss.

  1999cites this paper
• Impaired immune responses toward alloantigens and tumor cells but normal thymic selection in mice deficient in the beta2 integrin leukocyte function-associated antigen-1.

  1996cites this paper
• Monoclonal Antibodies to Adhesion Molecules in Bone Marrow and Organ Transplantation

  1995cites this paper
• Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways.

  1995cites this paper
• Natural killer cells in peripheral blood after autologous bone marrow transplantation: a combined phenotypic and functional study.

  1995cites this paper
• Interleukin-7 selectively enhances natural kill cytotoxicity mediated by the CD56bright natural killer subpopulation.

  1994cites this paper
• Inhibition of NK binding to K562 cells induced by MAb saturation of adhesion molecules on target membrane.

  1994cites this paper
• Identification of a Vimentin‐Like Function Associated Molecule (FAM) on Rat NK Cells: Evidence for Receptor Function

  1993cites this paper
• Expression of conformationally constrained adhesion peptide in an antibody CDR loop and inhibition of natural killer cell cytotoxic activity by an antibody antigenized with the RGD motif.

  1993cites this paper
• Modulation of leukemic cell sensitivity to lymphokine-activated killer cytolysis: role of intercellular adhesion molecule-1.

  1992cites this paper
• Modulation of adhesion molecules on human large granular lymphocytes by interleukin-2 in vivo and in vitro.

  1992cites this paper
• Induction of CD11a/leukocyte function antigen-1 and CD54/intercellular adhesion molecule-1 on hairy cell leukemia cells is accompanied by enhanced susceptibility to T-cell but not lymphokine-activated killer-cell cytotoxicity.

  1992cites this paper
• The superfamily of proteins with von Willebrand factor type A-like domains: one theme common to components of extracellular matrix, hemostasis, cellular adhesion, and defense mechanisms.

  1991cites this paper
• Defective T-lymphocyte signal transduction and function in leukocyte adhesion deficiency

  1991cites this paper
• A novel functional cell surface dimer (Kp43) expressed by natural killer cells and gamma/delta TCR+ T lymphocytes. II. Modulation of natural killer cytotoxicity by anti-Kp43 monoclonal antibody.

  1991cites this paper
• Human natural killer cell adhesion molecules. Differential expression after activation and participation in cytolysis.

  1990cites this paper
• Lymphocyte leukocyte function-associated antigen 1 interacting with target cell intercellular adhesion molecule 1 co-activates cytolysis triggered via CD16 or the receptor involved in major histocompatibility antigen-unrestricted lysis.

  1990cites this paper
• Evidence that anti-LFA-1 in vivo improves engraftment and survival after allogeneic bone marrow transplantation.

  1990cites this paper
• Distinct and Non-Cross-Reactive Epitopes are Recognized on B16 Melanoma by LAK Cells and Anti-B16 Monoclonal Antibodies

  1990cites this paper
• Characterization and utilization of a monoclonal antibody inhibiting porcine natural killer cell activity for isolation of natural killer and killer cells.

  1990cites this paper
• Participation of CD11a‐c/CD18, CD2 and ROD‐binding receptors in endogenous and interleukin‐2‐stimulated NK activity of CDS‐negative large granular lymphocytes

  1990cites this paper
• Leucocyte Adhesion to Cells

  1989cites this paper
• Leukocyte membrane adhesion proteins LFA-1, CR3 and p150,95: a review of functional and regulatory aspects.

  1989cites this paper
• Decreased Natural Killer (NK) Susceptibility of Human NK Target Cells after Phosphatidylinositol‐Specific Phospholipase C Treatment

  1989cites this paper
• The role of CD18 in phorbol ester-induced human monocyte-mediated cytotoxicity.

  1988cites this paper
• Functional domains of the CD11a adhesion molecule in lymphokine activated killer (LAK)-mediated cytolysis.

  1988cites this paper
• Adhesion-promoting receptors on phagocytes

  1988cites this paper
• CD11a-c/CD18 and GP84 (LB-2) adhesion molecules on human large granular lymphocytes and their participation in natural killing.

  1988cites this paper
• LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytes.

  1987cites this paper
• The role of monocyte lymphocyte function‐associated antigen 1 (LFA‐1) in accessory cell function

  1987cites this paper
• Alpha and beta subunits of the LFA‐1 membrane molecule are involved in human monocyte–endothelial cell adhesion

  1987cites this paper
• Membrane glycoprotein p150,95 of human cytotoxic T cell clone is involved in conjugate formation with target cells.

  1987cites this paper
• MEMBRANE GLYCOPROTEIN p i50,95 OF HUMAN CYTOTOXIC T CELL CLONES IS INVOLVED IN CONJUGATE FORMATION WITH TARGET CELLS1

  1987cites this paper
• Lymphocyte function-associated antigen 1 (LFA-1) and natural killer (NK) cell activity: LFA-1 is not necessary for all killer: target cell interactions.

  1987cites this paper
• Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones.

  1986cites this paper