Neuroprotection for diabetic retinopathy.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Developments in ophthalmology

• Publication date

  2009-06-03

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1159/000223946PMID 19494653
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2008cited by this paper
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  2007cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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• Diabetic Retinopathy

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  2005cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
• [Changes in IGF-I levels and its binding proteins in diabetes mellitus and obesity].

  2003cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1990cited by this paper
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  1989cited by this paper
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  1989cited by this paper

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