Proteasome Nuclear Import Mediated by Arc3 Can Influence Efficient DNA Damage Repair and Mitosis in Schizosaccharomyces Pombe

Proteasomes must efficiently remove their substrates throughout the cells in a timely manner as many of these proteins can be toxic. This study shows that proteasomes can do so efficiently because they are highly mobile. Furthermore this study uncovers that proteasome mobility requires functional Arc3, a subunit of the Arp2/3 complex.

• Publication year

  2010

• Venue

  Molecular Biology of the Cell

• Publication date

  2010-07-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/mbc.E10-06-0506PMID 20668161PMCID 2938379
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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