PRRX1 and PRRX2 distinctively participate in pituitary organogenesis and a cell-supply system

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Cell and Tissue Research

• Publication date

  2014-04-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00441-014-1861-5PMID 24770895
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1981cited by this paper

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