Inhibition of hypoxia‐associated response and kynurenine production in response to hyperbaric oxygen as mechanisms involved in protection against experimental cerebral malaria

No abstract is available for this paper.

• Publication year

  2018

• Venue

  The FASEB Journal

• Publication date

  2018-03-20

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1096/fj.201700844RPMID 29558201PMCID PMC6044055
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2017influential reference
• The kynurenine pathway and parasitic infections that affect CNS function.

  2017influential reference
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  2016influential reference
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  2014influential reference
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  2014influential reference
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  2012influential reference
• Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

  2012cited by this paper
• Heme oxygenase-1 and chronic hypoxia.

  2012cited by this paper
• Diagnosis, prognosis and treatment of severe falciparum malaria in African children

  2012cited by this paper
• The Neuropathology of Fatal Cerebral Malaria in Malawian Children

  2011cited by this paper
• CNS hypoxia is more pronounced in murine cerebral than noncerebral malaria and is reversed by erythropoietin.

  2011influential reference
• Specific Receptor Usage in Plasmodium falciparum Cytoadherence Is Associated with Disease Outcome

  2011cited by this paper
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  2009cited by this paper
• Interdependence of hypoxic and innate immune responses

  2009cited by this paper
• Blood brain barrier in hypoxic-ischemic conditions.

  2008cited by this paper
• Pathogenesis, clinical features and neurological outcome of cerebral malaria

  2008cited by this paper
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  2008cited by this paper
• Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria.

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• Pathogenesis, clinical features, and neurological outcome of cerebral malaria.

  2005cited by this paper
• The role of ICAM-1 in Plasmodium falciparum cytoadherence.

  2005cited by this paper
• Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease

  2005cited by this paper
• Experimental models of cerebral malaria.

  2005cited by this paper
• Simultaneous determination of tryptophan and kynurenine in serum by HPLC with UV and fluorescence detection.

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• HIF1 and oxygen sensing in the brain

  2004influential reference
• Heme oxygenase-1: unleashing the protective properties of heme.

  2003cited by this paper
• Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria.

  2003influential reference
• Oxidative stress and rheology in severe malaria

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  1997cited by this paper
• Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration.

  1985cited by this paper

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