Retinal pigment epithelium cell-derived exosomes: Possible relevance to CNV in wet-age related macular degeneration.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Medical Hypotheses

• Publication date

  2016-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.mehy.2016.10.027PMID 27876140
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Exosomes Mediate the Intercellular Communication after Myocardial Infarction

  2016cited by this paper
• Oxidative stress in retinal pigment epithelium cells increases exosome secretion and promotes angiogenesis in endothelial cells

  2016cited by this paper
• STAT3-regulated exosomal miR-21 promotes angiogenesis and is involved in neoplastic processes of transformed human bronchial epithelial cells.

  2016cited by this paper
• Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

  2015cited by this paper
• A Mouse Model for Laser-induced Choroidal Neovascularization.

  2015cited by this paper
• High-grade ovarian cancer secreting effective exosomes in tumor angiogenesis.

  2015cited by this paper
• Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells attenuate limb ischemia by promoting angiogenesis in mice

  2015cited by this paper
• A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization

  2015cited by this paper
• Glucose Starvation in Cardiomyocytes Enhances Exosome Secretion and Promotes Angiogenesis in Endothelial Cells

  2015cited by this paper
• Sorting it out: regulation of exosome loading.

  2014cited by this paper
• Interactions between Exosomes from Breast Cancer Cells and Primary Mammary Epithelial Cells Leads to Generation of Reactive Oxygen Species Which Induce DNA Damage Response, Stabilization of p53 and Autophagy in Epithelial Cells

  2014cited by this paper
• Extracellular vesicles: Exosomes, microvesicles, and friends

  2013cited by this paper
• Exosomes from Retinal Astrocytes Contain Antiangiogenic Components That Inhibit Laser-induced Choroidal Neovascularization*

  2013cited by this paper
• Exosomal proteins in the aqueous humor as novel biomarkers in patients with neovascular age-related macular degeneration.

  2013cited by this paper
• Blood/plasma secretome and microvesicles.

  2013cited by this paper
• Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress.

  2013cited by this paper
• Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats

  2013cited by this paper
• Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

  2013cited by this paper
• Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions

  2012cited by this paper
• Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types

  2012cited by this paper
• Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials.

  2012cited by this paper
• Age-related macular degeneration

  2012cited by this paper
• Retinal pigment epithelium response to oxidant injury in the pathogenesis of early age-related macular degeneration.

  2012cited by this paper
• A systematic review of the efficacy and safety outcomes of anti-VEGF agents used for treating neovascular age-related macular degeneration: comparison of ranibizumab and bevacizumab

  2011cited by this paper
• Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

  2011cited by this paper
• Exosomes and Cancer: A Newly Described Pathway of Immune Suppression

  2011cited by this paper
• The prevalence of age-related macular degeneration in Asians: a systematic review and meta-analysis.

  2010cited by this paper
• Therapeutic targets in age-related macular disease.

  2010cited by this paper
• Autophagy and Exosomes in the Aged Retinal Pigment Epithelium: Possible Relevance to Drusen Formation and Age-Related Macular Degeneration

  2009cited by this paper
• Urinary Exosomes

  2009cited by this paper
• Inflammation in the pathogenesis of age-related macular degeneration

  2008cited by this paper
• Prevalence of age-related macular degeneration in the United States.

  2004cited by this paper
• Exosomes: composition, biogenesis and function

  2002cited by this paper
• Common Eye Diseases of Elderly People: Identifying and Treating Causes of Vision Loss

  2002cited by this paper
• Cause-specific prevalence of bilateral visual impairment in Victoria, Australia: the Visual Impairment Project.

  2001cited by this paper

• Retinal pigment epithelium-derived extracellular vesicles mediate outer blood retinal barrier disruption in response to AMD-related stress

  2025cites this paper
• The role of secretory autophagy and exosomes in the accumulation of drusen during the development of age-related macular degeneration (AMD).

  2025cites this paper
• Metabolomic and Transcriptomic Analysis Reveals Metabolic-Immune Interactions in Choroid Neovascularization.

  2024cites this paper
• Selective microRNA expression of exosomes from retinal pigment epithelial cells by oxidative stress.

  2024cites this paper
• Small Extracellular Vesicles and Oxidative Pathophysiological Mechanisms in Retinal Degenerative Diseases

  2024cites this paper
• Extracellular vesicles: an emerging player in retinal homeostasis

  2023cites this paper
• Salivary Exosomes in Health and Disease: Future Prospects in the Eye

  2023cites this paper
• Research progress of exosomes in pathogenesis, diagnosis, and treatment of ocular diseases

  2023cites this paper
• Extracellular vesicles as a new horizon in the diagnosis and treatment of inflammatory eye diseases: A narrative review of the literature

  2023cites this paper
• Exosomal non-coding RNAs in angiogenesis: Functions, mechanisms and potential clinical applications

  2023cites this paper
• Endogenous and Exogenous Regulation of Redox Homeostasis in Retinal Pigment Epithelium Cells: An Updated Antioxidant Perspective

  2023cites this paper
• Age-Related Macular Degeneration - Therapies and their delivery.

  2023cites this paper
• Homeostasis and dyshomeostasis of the retina

  2023cites this paper
• Vitreous humor proteome: unraveling the molecular mechanisms underlying proliferative and neovascular vitreoretinal diseases

  2022cites this paper
• Differences in the Quantity and Composition of Extracellular Vesicles in the Aqueous Humor of Patients with Retinal Neovascular Diseases

  2021cites this paper
• Exosomes in the pathogenesis and treatment of ocular diseases.

  2021cites this paper
• Mitochondrial miRNA494-3p in extracellular vesicles participates in cellular interplay of iPS-Derived human retinal pigment epithelium with macrophages.

  2021cites this paper
• CD63+ extracellular vesicle from retinal pigment epithelial cells participate in crosstalk with macrophages in the innate inflammatory axis.

  2021cites this paper
• Microarray Analysis of Small Extracellular Vesicle-Derived miRNAs Involved in Oxidative Stress of RPE Cells

  2020cites this paper
• Extracellular Vesicle Transfer from Endothelial Cells Drives VE-Cadherin Expression in Breast Cancer Cells, Thereby Causing Heterotypic Cell Contacts

  2020cites this paper
• Exosomes derived from RPE cells under oxidative stress mediate inflammation and apoptosis of normal RPE cells through Apaf1/caspase‐9 axis

  2020cites this paper
• Roles of Exosomes in Ocular Diseases in intercellular communication

  2020influential citation
• Roles of Exosomes in Ocular Diseases

  2020influential citation
• Descriptive analysis of Fibulin-3 and the extracellular vesicle marker, Alix, in drusen from a small cohort of postmortem human eyes.

  2020cites this paper
• Interplay between Autophagy and the Ubiquitin-Proteasome System and Its Role in the Pathogenesis of Age-Related Macular Degeneration

  2019cites this paper
• Extracellular vesicle-mediated long-range communication in stressed retinal pigment epithelial cell monolayers.

  2018cites this paper
• IGF-1, Inflammation and Retinal Degeneration: A Close Network

  2018cites this paper
• Epigenetic modifications in hyperhomocysteinemia: potential role in diabetic retinopathy and age-related macular degeneration

  2018cites this paper