A xanthine oxidase inhibitor 1'-acetoxychavicol acetate inhibits azoxymethane-induced colonic aberrant crypt foci in rats.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Carcinogenesis

• Publication date

  1997-05-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1093/CARCIN/18.5.1113PMID 9163704
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chemopreventive Effect of a Xanthine Oxidase Inhibitor, 1′‐Acetoxychavicol Acetate, on Rat Oral Carcinogenesis

  1996cited by this paper
• Regional distribution of carcinogen-induced colonic neoplasia in the rat.

  1996cited by this paper
• Chemoprevention of digestive organs carcinogenesis by natural product protocatechuic acid

  1995cited by this paper
• Regional chemoprevention of carcinogen-induced tumors in rat colon.

  1995cited by this paper
• Cancer chemoprevention agent development strategies for genistein.

  1995cited by this paper
• Role of aberrant crypt foci in understanding the pathogenesis of colon cancer.

  1995cited by this paper
• Antioxidant and Antipromotional Effects of the Soybean Isoflavone Genistein

  1995cited by this paper
• Oxy-radicals and cancer.

  1994cited by this paper
• Cancer chemoprevention by natural-products (review).

  1994cited by this paper
• Use of azoxymethane-induced foci of aberrant crypts in rat colon to identify potential cancer chemopreventive agents.

  1994cited by this paper
• Chemoprevention of cancer.

  1994cited by this paper
• Oxidative mechanisms in carcinogenesis.

  1993cited by this paper
• 1'-Acetoxychavicol Acetate as a Potent Inhibitor of Tumor Promoter-induced Epstein-Barr Virus Activation from Languas galanga, a Traditional Thai Condiment

  1993cited by this paper
• Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid: suppressing effects on tumor development and biomarkers expression of colon tumorigenesis.

  1993cited by this paper
• Chemopreventive effects of green tea components on hepatic carcinogenesis.

  1992cited by this paper
• Aberrant crypts correlate with tumor incidence in F344 rats treated with azoxymethane and phytate.

  1992cited by this paper
• Growth kinetics and chemoprevention of aberrant crypts in the rat colon

  1992cited by this paper
• Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence.

  1992cited by this paper
• Sequential analyses of the growth and morphological characteristics of aberrant crypt foci: putative preneoplastic lesions.

  1991cited by this paper
• Inhibition of Azoxymethane‐induced Colon Carcinogenesis in Rat by Green Tea Polyphenol Fraction

  1991cited by this paper
• Oxidant stress and carcinogenesis

  1991cited by this paper
• Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia.

  1991cited by this paper
• Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase.

  1991cited by this paper
• Aberrant crypts: putative preneoplastic foci in human colonic mucosa.

  1991cited by this paper
• Cell proliferation in carcinogenesis.

  1990cited by this paper
• Inhibition of Carcinogenesis by minor Anutrient Constituents of the Diet

  1990cited by this paper
• Primary prevention of colorectal cancer. The WHO Collaborating Centre for the Prevention of Colorectal Cancer.

  1990cited by this paper
• Xanthine oxidase levels in human brain tumors.

  1990cited by this paper
• Murine epidermal xanthine oxidase activity: correlation with degree of hyperplasia induced by tumor promoters.

  1987cited by this paper
• Xanthine oxidase: biochemistry, distribution and physiology.

  1986cited by this paper
• Activation of the colon carcinogen 1,2-dimethylhydrazine in a rat colon cell-mediated mutagenesis assay.

  1986cited by this paper
• Chemoprevention of cancer.

  1985cited by this paper
• Site-specific induction of nuclear anomalies (apoptotic bodies and micronuclei) by carcinogens in mice.

  1984cited by this paper
• Non-alcohol dehydrogenase-mediated metabolism of methylazoxymethanol in the deer mouse, Peromyscus maniculatus.

  1984cited by this paper
• Nuclear aberrations as a short-term test for genotoxicity to the colon: evaluation of nineteen agents in mice.

  1983cited by this paper
• Metabolism of the colon carcinogen methylazoxymethanol acetate.

  1979cited by this paper
• Inhibition of the metabolism of the colon carcinogen, azoxymethane, by pyrazole.

  1978cited by this paper
• Investigations into the metabolism and mode of action of the colon carcinogens 1,2‐dimethylhydrazine and azoxymethane

  1977cited by this paper
• Inhibitors of colon carcinogenesis

  1977cited by this paper
• Effects of disulfiram and related compounds on the metabolism in vivo of the colon carcinogen, 1,2-dimethylhydrazine.

  1977cited by this paper
• Constituents from seeds of Alpinia galanga Wild, and their anti-ulcer activities.

  1976cited by this paper
• The reduction of cytochrome c by milk xanthine oxidase.

  1968cited by this paper

• Development and validation of a reversed-phase HPLC method for quantification of 1’-acetoxychavicol acetate content in a nanostructured lipid carrier formulation

  2022cites this paper
• Assessment of Antigout, Antioxidant and Production Performance Augmenting Activity of Piper betle L. in Gout Induced Broiler Chicken

  2021cites this paper
• Therapeutic antigout and antioxidant activity of Piper betle L. in gout-induced broilers

  2021cites this paper
• Identification of Antimutagenic Substances ( Ames Test ) from Boesenbergia pandurata Sehl

  2018cites this paper
• Novel purification of 1'S-1'-Acetoxychavicol acetate from Alpinia galanga and its cytotoxic plus antiproliferative activity in colorectal adenocarcinoma cell line SW480.

  2017cites this paper
• Screening for the of Edible Plantsin Vitro Anti-tumor-promoting from Malaysia Activities

  2017cites this paper
• Anti-proliferative, apoptotic induction, and anti-migration effects of hemi-synthetic 1′S-1′-acetoxychavicol acetate analogs on MDA-MB-231 breast cancer cells

  2017cites this paper
• Role of Nutrition in Oral and Pharyngeal Cancers: From Etiology to Prevention

  2017cites this paper
• 1'-Acetoxychavicol acetate ameliorates age-related spatial memory deterioration by increasing serum ketone body production as a complementary energy source for neuronal cells.

  2016cites this paper
• Anticancer Potentials of Internal Cold-Dispelling Herbs

  2016cites this paper
• Virtual Screening of 1'-Acetoxychavicol Acetate, Zerumbone, Auraptene, and Nobiletin as Cyclooxygenase Inhibitors

  2012cites this paper
• 1'-Acetoxychavicol acetate enhances the phase II enzyme activities via the increase in intranuclear Nrf2 level and cytosolic p21 level.

  2011cites this paper
• Comparison of glutathione reductase activity and the intracellular glutathione reducing effects of 13 derivatives of 1'-acetoxychavicol acetate in Ehrlich ascites tumor cells.

  2010cites this paper
• The Apoptotic Effect of 1’S-1’-Acetoxychavicol Acetate from Alpinia Conchigera on Human Cancer Cells

  2010cites this paper
• (1'S)-Acetoxychavicol acetate and its enantiomer inhibit tumor cells proliferation via different mechanisms.

  2008cites this paper
• Anti-Gout Agent Allopurinol Exerts Cytotoxicity to Human Hormone-Refractory Prostate Cancer Cells in Combination with Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand

  2008cites this paper
• Structural development of benzhydrol-type 1'-acetoxychavicol acetate (ACA) analogs as human leukemia cell-growth inhibitors based on quantitative structure-activity relationship (QSAR) analysis.

  2008cites this paper
• 1′-Acetoxychavicol acetate-induced cytotoxicity is accompanied by a rapid and drastic modulation of glutathione metabolism

  2008cites this paper
• Modulation of MAPK Pathways by Food Phytochemicals: Risks and Benefits

  2008cites this paper
• Aberrant crypt foci and AgNORs as putative biomarkers to evaluate the chemopreventive efficacy of pronyl-lysine in rat colon carcinogenesis

  2008cites this paper
• Inhibition of Colon Carcinogenesis by Dietary Non-Nutritive Compounds

  2007cites this paper
• Structure-activity relationships of 1'-acetoxychavicol acetate homologues as new nuclear export signal inhibitors.

  2007cites this paper
• Cellular thiol status-dependent inhibition of tumor cell growth via modulation of p27kip1 translocation and retinoblastoma protein phosphorylation by 1′-acetoxychavicol acetate

  2007cites this paper
• The effects of allopurinol on rat liver and spleen tissues in a chronic hyperammonemia animal model.

  2007cites this paper
• Suppressive effects of dietary factors on the expression of scavenger receptors and underlying molecular mechanisms

  2007cites this paper
• Cancer-preventive anti-oxidants that attenuate free radical generation by inflammatory cells

  2006cites this paper
• Induction of apoptosis via the modulation of reactive oxygen species (ROS) production in the treatment of myeloid leukemia.

  2006cites this paper
• New Therapeutic Approach for Myeloid Leukemia: Induction of Apoptosis via Modulation of Reactive Oxygen Species Production by Natural Compounds

  2006cites this paper
• 1'S-1'-acetoxychavicol acetate isolated from Alpinia galanga inhibits human immunodeficiency virus type 1 replication by blocking Rev transport.

  2006cites this paper
• Novel bioassay system for evaluating anti-oxidative activities of food items: Use of basolateral media from differentiated Caco-2 cells

  2005cites this paper
• 1'-Acetoxychavicol acetate induces apoptosis of myeloma cells via induction of TRAIL.

  2005cites this paper
• The phenolic compounds of olive oil: structure, biological activity and beneficial effects on human health

  2005cites this paper
• Suppressive effects of Okinawan food items on free radical generation from stimulated leukocytes and identification of some active constituents: implications for the prevention of inflammation-associated carcinogenesis.

  2005cites this paper
• 1'-acetoxychavicol acetate is a novel nuclear factor kappaB inhibitor with significant activity against multiple myeloma in vitro and in vivo.

  2005cites this paper
• Identification of a Novel Blocker of IκBα Kinase That Enhances Cellular Apoptosis and Inhibits Cellular Invasion through Suppression of NF-κB-Regulated Gene Products1

  2005cites this paper
• Aberrant crypt foci and beta-catenin accumulated crypts; significance and roles for colorectal carcinogenesis.

  2004cites this paper
• Modifying Effects of 1'-Acetoxychavicol Acetate (ACA) and the Novel Synthetic Retinoids Re-80, Am-580 and Am-55P in a Two-Stage Carcinogenesis Model in Female Rats

  2004cites this paper
• Inhibition of xanthine oxidase by phytic acid and its antioxidative action.

  2004cites this paper
• An NMR method towards the routine chiral determination of natural products.

  2004cites this paper
• Induction of Apoptosis in Human Myeloid Leukemic Cells by 1′-Acetoxychavicol Acetate through a Mitochondrial- and Fas-Mediated Dual Mechanism

  2004cites this paper
• Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-γ-induced IκB degradation in RAW264.7 macrophages

  2003cites this paper
• Mutagenicity of reactive oxygen and nitrogen species as detected by co-culture of activated inflammatory leukocytes and AS52 cells.

  2003cites this paper
• Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-gamma-induced IkappaB degradation in RAW264.7 macrophages.

  2003cites this paper
• Screening of edible Japanese plants for suppressive effects on phorbol ester-induced superoxide generation in differentiated HL-60 cells and AS52 cells.

  2002cites this paper
• Most Effective Colon Cancer Chemopreventive Agents in Rats: A Systematic Review of Aberrant Crypt Foci and Tumor Data, Ranked by Potency

  2002cites this paper
• Involvement of protein tyrosine phosphorylation and reduction of cellular sulfhydryl groups in cell death induced by 1' -acetoxychavicol acetate in Ehrlich ascites tumor cells.

  2002cites this paper
• Chemoprevention of Colon Carcinogenesis by Dietary Non-nutritive Compounds.

  2001influential citation
• Dietary administration of citrus nobiletin inhibits azoxymethane-induced colonic aberrant crypt foci in rats.

  2001cites this paper
• Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats.

  2001cites this paper
• Chemoprevention of azoxymethane-induced rat aberrant crypt foci by dietary zerumbone isolated from Zingiber zerumbet.

  2001cites this paper
• A catechol antioxidant protocatechuic acid potentiates inflammatory leukocyte-derived oxidative stress in mouse skin via a tyrosinase bioactivation pathway.

  2001cites this paper
• Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignansand squalene.

  2000cites this paper
• A simple phenolic antioxidant protocatechuic acid enhances tumor promotion and oxidative stress in female ICR mouse skin: dose-and timing-dependent enhancement and involvement of bioactivation by tyrosinase.

  2000cites this paper
• Novel nitric oxide and superoxide generation inhibitors, persenone A and B, from avocado fruit.

  2000cites this paper
• Apoptosis induced by 1'-acetoxychavicol acetate in Ehrlich ascites tumor cells is associated with modulation of polyamine metabolism and caspase-3 activation.

  2000cites this paper
• The antioxidant/anticancer potential of phenolic compounds isolated from olive oil.

  2000cites this paper
• Inhibitory Effects of 1′‐Acetoxychavicol Acetate on N‐Nitrosobis(2‐oxopropyl)‐amine‐induced Initiation of Cholangiocarcinogenesis in Syrian Hamsters

  2000cites this paper
• Suppression by citrus auraptene of phorbol ester-and endotoxin-induced inflammatory responses: role of attenuation of leukocyte activation.

  2000cites this paper
• Structure-activity relationships of (1'S)-1'-acetoxychavicol acetate, a major constituent of a southeast Asian condiment plant Languas galanga, on the inhibition of tumor-promoter-induced Epstein-Barr virus activation.

  2000cites this paper
• Screening for the In Vitro Anti-tumor-promoting Activities of Edible Plants from Malaysia

  2000cites this paper
• Chemoprevention: Insights into biological mechanisms and promising food factors

  1999cites this paper
• CANCER CHEMOPREVENTION BY FOOD PHYTOCHEMICALS REGULATING INFLAMMATORY LEUKOCYTES(植物性食品因子による炎症性白血球の制御とがんの化学予防)

  1998cites this paper
• Chemoprevention with Food Phytochemicals: Screening, Rodent Studies, and Action Mechanisms

  1998influential citation
• Suppression of tumor promoter-induced oxidative stress and inflammatory responses in mouse skin by a superoxide generation inhibitor 1'-acetoxychavicol acetate.

  1998cites this paper
• Inhibition by 1'-acetoxychavicol acetate of lipopolysaccharide- and interferon-gamma-induced nitric oxide production through suppression of inducible nitric oxide synthase gene expression in RAW264 cells.

  1998cites this paper
• Screening of edible Japanese plants for nitric oxide generation inhibitory activities in RAW 264.7 cells.

  1998cites this paper
• Niaziminin, a thiocarbamate from the leaves of Moringa oleifera, holds a strict structural requirement for inhibition of tumor-promoter-induced Epstein-Barr virus activation.

  1998cites this paper
• Screening for in vitro anti-tumor-promoting activities of edible plants from Indonesia.

  1998cites this paper
• Prevention by 1'-acetoxychavicol acetate of the induction but not growth of putative preneoplastic, glutathione S-transferase placental form-positive, focal lesions in the livers of rats fed a choline-deficient, L-amino acid-defined diet.

  1998cites this paper
• Acetoxychavicol Acetate ′ Generation Inhibitor 1 Inflammatory Responses in Mouse Skin by a Superoxide Suppression of Tumor Promoter-induced Oxidative Stress and Updated

  1998cites this paper
• Chemoprevention of Azoxymethane‐induced Rat Colon Carcinogenesis by a Xanthine Oxidase Inhibitor, 1′‐Acetoxychavicol Acetate

  1997cites this paper
• Auraptene, a Citrus Coumarin, Inhibits 12‐0‐Tetradecanoylphorbol‐13‐acetate‐induced Tumor Promotion in ICR Mouse Skin, Possibly through Suppression of Superoxide Generation in Leukocytes

  1997cites this paper
• anti-proliferative, apoptotic induction, and anti-migration effects of hemi-synthetic 1 ′ S -1 ′ -acetoxychavicol acetate analogs on MDa-MB-231 breast cancer cells

  year unknowncites this paper