The role of IGFBP3 functional polymorphisms in the risk of gastric cancer in a high-risk Chinese population

No abstract is available for this paper.

• Publication year

  2008

• Venue

  European Journal of Cancer Prevention

• Publication date

  2008-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/CEJ.0b013e32809b4cffPMID 18287864
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Polymorphisms of genes coding for insulin-like growth factor 1 and its major binding proteins, circulating levels of IGF-I and IGFBP-3 and breast cancer risk: results from the EPIC study

  2006influential reference
• IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer.

  2006influential reference
• Polymorphisms in insulin-related genes predispose to specific KRAS2 and TP53 mutations in colon cancer.

  2006cited by this paper
• IGF-I, IGFBP-3 and breast cancer in young women: a pooled re-analysis of three prospective studies

  2005cited by this paper
• A new single nucleotide polymorphism in the insulin-like growth factor I regulatory region associates with colorectal cancer risk in singapore chinese.

  2005cited by this paper
• Association of an Exon 1 Polymorphism in the IGFBP3 Gene with Circulating IGFBP-3 Levels and Colorectal Cancer Risk: The Multiethnic Cohort Study

  2005cited by this paper
• Variation in Plasma Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3: Genetic Factors

  2005influential reference
• The A(-336C) insulin-like growth factor binding protein-3 promoter polymorphism is not a modulator of breast cancer risk in Caucasian women.

  2005cited by this paper
• Insulin-like growth factor binding protein-3: relationship to the development of gastric pre-malignancy and gastric adenocarcinoma (United Kingdom)

  2004influential reference
• Genetic polymorphisms in the IGFBP3 gene: association with breast cancer risk and blood IGFBP-3 protein levels among Chinese women.

  2004influential reference
• No association between genetic polymorphisms in IGF-I and IGFBP-3 and prostate cancer.

  2004cited by this paper
• Associations among IRS1, IRS2, IGF1, and IGFBP3 genetic polymorphisms and colorectal cancer.

  2004cited by this paper
• Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis.

  2004cited by this paper
• Polymorphic variation at the ‐202 locus in IGFBP3: Influence on serum levels of insulin‐like growth factors, interaction with plasma retinol and vitamin D and breast cancer risk

  2003influential reference
• Insulin-like growth factor-binding protein-3 gene -202 A/C polymorphism is correlated with advanced disease status in prostate cancer.

  2003cited by this paper
• Insulin-like growth factors and cancer.

  2002cited by this paper
• IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms.

  2002cited by this paper
• Insulin-like growth factor I, IGF-binding protein 3, and lung cancer risk in a prospective study of men in China.

  2002cited by this paper
• Genetic and nongenetic factors associated with variation of plasma levels of insulin-like growth factor-I and insulin-like growth factor-binding protein-3 in healthy premenopausal women.

  2001influential reference
• Insulin-like growth factor-binding protein 1 stimulates human trophoblast migration by signaling through alpha 5 beta 1 integrin via mitogen-activated protein Kinase pathway.

  2001cited by this paper
• Mutation of three critical amino acids of the N-terminal domain of IGF-binding protein-3 essential for high affinity IGF binding.

  2001cited by this paper
• GSTP1 polymorphisms and gastric cancer in a high-risk Chinese population

  2001cited by this paper
• Insulin-Like Growth Factor-Binding Protein 1 Stimulates Human Trophoblast Migration by Signaling through α5β1 Integrin via Mitogen-Activated Protein Kinase Pathway1

  2001cited by this paper
• Novel promoter polymorphism in insulin-like growth factor-binding protein-3: correlation with serum levels and interaction with known regulators.

  2001influential reference
• Role of the insulin-like growth factor family in cancer development and progression.

  2000cited by this paper
• The effects of insulin-like growth factors on tumorigenesis and neoplastic growth.

  2000cited by this paper
• Insulin-like growth factor physiology and cancer risk.

  2000cited by this paper
• Substitutions for Hydrophobic Amino Acids in the N-terminal Domains of IGFBP-3 and -5 Markedly Reduce IGF-I Binding and Alter Their Biologic Actions*

  2000cited by this paper
• Response: More About: Prospective Study of Colorectal Cancer Risk in Men and Plasma Levels of Insulin-Like Growth Factor (IGF)-I and IGF- Binding Protein-3

  1999cited by this paper
• Effect of insulin-like growth factor binding protein-1 on integrin signalling and the induction of apoptosis in human breast cancer cells.

  1999cited by this paper
• Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.

  1999cited by this paper
• Screening for Mutations in the Promoter and the Coding Region of the IGFBP1 and IGFBP3 Genes in Silver-Russell Syndrome Patients

  1999cited by this paper
• Insulin and IGF binding by IGFBP-3 fragments derived from proteolysis, baculovirus expression and normal human urine.

  1998cited by this paper
• Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues.

  1998cited by this paper
• Genetic and environmental components of interindividual variation in circulating levels of IGF-I, IGF-II, IGFBP-1, and IGFBP-3.

  1996cited by this paper
• Insulin-like Growth Factors and Cancer

  1995influential reference
• Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence.

  1993cited by this paper

• IGF2 enhanced the osteo-/dentinogenic and neurogenic differentiation potentials of stem cells from apical papilla.

  2020cites this paper
• Chapter 5 Helicobacter pylori Infection and Gastric Cancer — Is Eradication Enough to Prevent Gastric Cancer

  2018cites this paper
• Polymorphisms of insulin-like growth factor binding protein-3 as a predictor for risk and patient survival in esophageal squamous cell carcinoma.

  2015cites this paper
• Role of insulin-like growth factor-binding proteins in the pathophysiology and tumorigenesis of gastroesophageal cancers

  2015cites this paper
• Lack of association of IGFBP-3 gene polymorphisms with colorectal cancer: evidence from 17,380 subjects

  2014influential citation
• Helicobacter pylori Infection and Gastric Cancer — Is Eradication Enough to Prevent Gastric Cance

  2014cites this paper
• Association between endometriosis and polymorphisms in insulin-like growth factor binding protein genes in Korean women.

  2012cites this paper
• Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer.

  2012cites this paper
• ASSOCIATION OF IGFBP3 GENE (RS2854744) POLYMORPHISM AND COLORECTAL CANCER

  2012cites this paper
• Association between endometriosis and polymorphisms in insulin-like growth factor binding protein genes in korean women

  2011cites this paper
• Epstein-Barr virus-specific methylation of human genes in gastric cancer cells

  2010cites this paper
• Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: evidence from 96 studies

  2009cites this paper
• Cell proliferation-related genetic polymorphisms and gastric cancer risk: systematic review and meta-analysis

  2009cites this paper
• IGFBP3 polymorphisms and risk of cancer: a meta-analysis

  2009influential citation
• Association of transforming growth factor-beta 1 polymorphisms with genetic susceptibility to TNM stage I or II gastric cancer.

  2008cites this paper