Coagulation factor Xa synergistically interacts with serotonin in inducing vascular smooth muscle cell proliferation.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Cardiovascular Radiation Medicine

• Publication date

  2003-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S1522-1865(03)00144-6PMID 14581086
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Randomized Double-blind Placebo-controlled Trial

  2004cited by this paper
• Factor Xa Releases Matrix Metalloproteinase-2 (MMP-2) From Human Vascular Smooth Muscle Cells and Stimulates the Conversion of Pro–MMP-2 to MMP-2: Role of MMP-2 in Factor Xa–Induced DNA Synthesis and Matrix Invasion

  2002influential reference
• Lysophosphatidylcholine and Reactive Oxygen Species Mediate the Synergistic Effect of Mildly Oxidized LDL With Serotonin on Vascular Smooth Muscle Cell Proliferation

  2001cited by this paper
• Factor Xa is a fibroblast mitogen via binding to effector-cell protease receptor-1 and autocrine release of PDGF.

  2001cited by this paper
• Serotonin potentiates angiotensin II--induced vascular smooth muscle cell proliferation.

  2001cited by this paper
• Angiotensin II and serotonin potentiate endothelin-1-induced vascular smooth muscle cell proliferation

  2001cited by this paper
• Lipid peroxidation product 4-hydroxy-2-nonenal acts synergistically with serotonin in inducing vascular smooth muscle cell proliferation.

  2001cited by this paper
• Synergistic effect of urotensin II with serotonin on vascular smooth muscle cell proliferation

  2001cited by this paper
• Synergistic effect of urotensin II with serotonin on vascular smooth muscle cell proliferation.

  2001cited by this paper
• Factor Xa Activates Endothelial Cells by a Receptor Cascade Between EPR-1 and PAR-2

  2000cited by this paper
• Hyperlipemic-very low density lipoprotein, intermediate density lipoprotein and low density lipoprotein act synergistically with serotonin on vascular smooth muscle cell proliferation.

  2000cited by this paper
• Factor Xa Acts as a PDGF-Independent Mitogen in Human Vascular Smooth Muscle Cells

  2000influential reference
• A synthetic inhibitor of factor Xa, DX-9065a, reduces proliferation of vascular smooth muscle cells in vivo in rats.

  2000influential reference
• Synergy between thrombin and serotonin in inducing vascular smooth muscle cell proliferation.

  1999cited by this paper
• Activation of human vascular endothelial cells by factor Xa: effect of specific inhibitors.

  1999cited by this paper
• Vascular smooth muscle proliferation: synergistic interaction between serotonin and low density lipoproteins.

  1999cited by this paper
• Effector protease receptor 1 mediates the mitogenic activity of factor Xa for vascular smooth muscle cells in vitro and in vivo.

  1998influential reference
• A new role for an old molecule: serotonin as a mitogen.

  1997cited by this paper
• Effect of serotonin, thromboxane A2, and specific receptor antagonists on vascular smooth muscle cell proliferation.

  1997cited by this paper
• Factor XII-induced mitogenesis is mediated via a distinct signal transduction pathway that activates a mitogen-activated protein kinase.

  1996cited by this paper
• Coagulation factor Xa stimulates platelet-derived growth factor release and mitogenesis in cultured vascular smooth muscle cells of rat.

  1996influential reference
• Reduced acute thrombus formation results in decreased neointimal proliferation after coronary angioplasty.

  1995cited by this paper
• International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

  1994cited by this paper
• Specific factor Xa inhibition reduces restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits.

  1994influential reference
• Smooth muscle cells and the pathogenesis of the lesions of atherosclerosis.

  1993cited by this paper
• Evaluation of Ketanserin in the Prevention of Restenosis After Percutaneous Transluminal Coronary Angioplasty A Multicenter Randomized Double‐Blind Placebo‐Controlled Trial

  1993cited by this paper
• Coagulation factors X, Xa, and protein S as potent mitogens of cultured aortic smooth muscle cells.

  1992influential reference
• 5-HT2 receptor mRNA is overexpressed in cultured rat aortic smooth muscle cells relative to normal aorta.

  1992cited by this paper
• Frequency and severity of cyclic flow alternations and platelet aggregation predict the severity of neointimal proliferation following experimental coronary stenosis and endothelial injury.

  1991cited by this paper
• Prevention of restenosis after percutaneous transluminal coronary angioplasty with thromboxane A2-receptor blockade. A randomized, double-blind, placebo-controlled trial. Coronary Artery Restenosis Prevention on Repeated Thromboxane-Antagonism Study (CARPORT).

  1991cited by this paper
• Prevention of Restenosis After Percutaneous Transluminal Coronary Angioplasty With Thromboxane A2‐Receptor Blockade: A Randomized, Double‐Blind, Placebo‐Controlled Trial

  1991cited by this paper
• Factors influencing restenosis after coronary angioplasty.

  1990cited by this paper
• Cellular Interactions, Growth Factors, and Smooth Muscle Proliferation in Atherogenesis a

  1990cited by this paper
• Deendothelialization in vivo initiates a thrombogenic reaction at the rabbit aorta surface. Correlation of uptake of fibrinogen and antithrombin III with thrombin generation by the exposed subendothelium.

  1989cited by this paper
• The molecular basis of blood coagulation.

  1988cited by this paper
• Role of platelets in atherogenesis: relevance to coronary arterial restenosis after angioplasty.

  1987cited by this paper
• Stimulation of aortic smooth muscle cell mitogenesis by serotonin.

  1986cited by this paper
• Production of platelet-derived growth factor-like molecules by cultured arterial smooth muscle cells accompanies proliferation after arterial injury.

  1986cited by this paper
• Serotonin receptor-mediated stimulation of bovine smooth muscle cell prostacyclin synthesis and its modulation by platelet-derived growth factor.

  1981cited by this paper
• Platelet activity in pathogenesis of atherosclerosis.

  1976cited by this paper

• Put out the fire: The pleiotropic anti-inflammatory action of non-vitamin K oral anticoagulants.

  2022cites this paper
• Nonhemostatic Activities of Factor Xa: Are There Pleiotropic Effects of Anti-FXa Direct Oral Anticoagulants?

  2019cites this paper
• 3 Roles of Serotonin in Atherothrombosis and Related Diseases

  2018cites this paper
• Chapter 15 – Gene Therapy for the Prevention of Vein Graft Disease

  2015cites this paper
• Gene therapy for the prevention of vein graft disease.

  2013cites this paper
• Roles of Serotonin in Atherothrombosis and Related Diseases

  2012cites this paper
• Traditional and Novel Risk Factors in Atherothrombosis

  2012cites this paper
• Blood coagulation factor Xa as an emerging drug target

  2011cites this paper
• Factor Xa: at the crossroads between coagulation and signaling in physiology and disease.

  2008cites this paper
• Coagulation factor Xa drives tumor cells into apoptosis through BH3-only protein Bim up-regulation.

  2006cites this paper