Modulation of Abnormal Metabolic Brain Networks by Experimental Therapies in a Nonhuman Primate Model of Parkinson Disease: An Application to Human Retinal Pigment Epithelial Cell Implantation

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Nuclear Medicine

• Publication date

  2016-04-07

• Fields of study

  Medicine

• Identifiers
  DOI 10.2967/jnumed.115.161513PMID 27056614PMCID PMC5367445
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neonatal human retinal pigment epithelial cells secrete limited trophic factors in vitro and in vivo following striatal implantation in parkinsonian rats

  2016cited by this paper
• Reproducibility of a Parkinsonism‐related metabolic brain network in non‐human primates: A descriptive pilot study with FDG PET

  2015cited by this paper
• Characterization of disease‐related covariance topographies with SSMPCA toolbox: Effects of spatial normalization and PET scanners

  2014cited by this paper
• Metabolic brain network in the Chinese patients with Parkinson's disease based on 18F-FDG PET imaging.

  2013cited by this paper
• Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating "clinical proof-of-concept" for AAV-neurturin (CERE-120) in Parkinson's disease.

  2013cited by this paper
• PET Demonstrates Functional Recovery After Transplantation of Induced Pluripotent Stem Cells in a Rat Model of Cerebral Ischemic Injury

  2013cited by this paper
• Validation of parkinsonian disease‐related metabolic brain patterns

  2013cited by this paper
• A randomized trial of mesenchymal stem cells in multiple system atrophy

  2012cited by this paper
• Transplantation of Human Retinal Pigment Epithelium Cells in the Treatment for Parkinson Disease

  2012cited by this paper
• PEDF and VEGF-A Output from Human Retinal Pigment Epithelial Cells Grown on Novel Microcarriers

  2012cited by this paper
• Abnormal Metabolic Brain Networks in a Nonhuman Primate Model of Parkinsonism

  2012cited by this paper
• Serial 18F-FDG PET Demonstrates Benefit of Human Mesenchymal Stem Cells in Treatment of Intracerebral Hematoma: A Translational Study in a Primate Model

  2011cited by this paper
• Longitudinal evolution of compensatory changes in striatal dopamine processing in Parkinson's disease.

  2011cited by this paper
• Progression of monoaminergic dysfunction in Parkinson's disease: A longitudinal 18F-dopa PET study

  2011cited by this paper
• Intrastriatal transplantation of microcarrier-bound human retinal pigment epithelial cells versus sham surgery in patients with advanced Parkinson's disease: a double-blind, randomised, controlled trial.

  2011cited by this paper
• Dopamine cell transplantation in Parkinson's disease: challenge and perspective.

  2011cited by this paper
• Dopamine Cell Implantation in Parkinson's Disease: Long-Term Clinical and 18F-FDOPA PET Outcomes

  2010cited by this paper
• Metabolic brain networks in neurodegenerative disorders: a functional imaging approach.

  2009cited by this paper
• Pathologic findings in retinal pigment epithelial cell implantation for Parkinson disease

  2009cited by this paper
• Pathologic findings in retinal pigment epithelial cell implantation for Parkinson's disease

  2009cited by this paper
• Spheramine for treatment of Parkinson’s disease

  2008influential reference
• Characterization and Survival of Long-Term Implants of Human Retinal Pigment Epithelial Cells Attached to Gelatin Microcarriers in a Model of Parkinson Disease

  2007cited by this paper
• Human Retinal Pigment Epithelial Cell Implants Ameliorate Motor Deficits in Two Rat Models of Parkinson Disease

  2007cited by this paper
• Subthalamic Glutamic Acid Decarboxylase Gene Therapy: Changes in Motor Function and Cortical Metabolism

  2007cited by this paper
• Abnormal Metabolic Network Activity in Parkinson'S Disease: Test—Retest Reproducibility

  2007cited by this paper
• Modulation of metabolic brain networks after subthalamic gene therapy for Parkinson's disease

  2007cited by this paper
• Network modulation in the treatment of Parkinson's disease.

  2006cited by this paper
• Intrastriatal implantation of human retinal pigment epithelial cells attached to microcarriers in advanced Parkinson disease.

  2005cited by this paper
• PET imaging of implanted human retinal pigment epithelial cells in the MPTP-induced primate model of Parkinson's disease.

  2004cited by this paper
• Stereotaxic intrastriatal implantation of human retinal pigment epithelial (hRPE) cells attached to gelatin microcarriers: a potential new cell therapy for Parkinson's disease.

  2003cited by this paper
• Mapping of brain function after MPTP-induced neurotoxicity in a primate Parkinson's disease model

  2003cited by this paper
• Striatal Xenotransplantation of Human Retinal Pigment Epithelial Cells Attached to Microcarriers in Hemiparkinsonian Rats Ameliorates Behavioral Deficits without Provoking a Host Immune Response

  2002cited by this paper
• Template Images for Nonhuman Primate Neuroimaging: 2. Macaque

  2001influential reference

• Positron Emission Tomography Imaging in Clinical Trials for Parkinson's Disease: Applications of Metabolic Brain Network Approach

  2025cites this paper
• Content CN-21-5

  2023cites this paper
• 1140Clinical Considerations in Parkinson's Disease Cell Therapy.

  2022cites this paper
• Dynamic 18F-FPCIT PET: Quantification of Parkinson Disease Metabolic Networks and Nigrostriatal Dopaminergic Dysfunction in a Single Imaging Session

  2021cites this paper
• Induced Cognitive Impairments Reversed by Grafts of Neural Precursors: a Longitudinal Study in a Macaque Model of Parkinson’s Disease

  2021cites this paper
• Title : Neural precursor grafts restore motor and non-motor functions in 1 parkinsonian macaques

  2021cites this paper
• Neuroimaging evaluation of deep brain stimulation in the treatment of representative neurodegenerative and neuropsychiatric disorders

  2021cites this paper
• Comparative test-retest variability of outcome parameters derived from brain [18F]FDG PET studies in non-human primates

  2020cites this paper
• Use of positron-emission tomography as a diagnostic and differential diagnostic tool in parkinsonian syndromes

  2020cites this paper
• Shared cerebral metabolic pathology in non-transgenic animal models of Alzheimer's and Parkinson's disease

  2020cites this paper
• Identifying a glucose metabolic brain pattern in an adeno-associated viral vector based rat model for Parkinson’s disease using 18F-FDG PET imaging

  2019cites this paper
• Network Imaging in Parkinsonian and Other Movement Disorders: Network Dysfunction and Clinical Correlates.

  2019cites this paper
• The role and mechanism of microRNA 184 in MPTP-induced nerve damage

  2019cites this paper
• The effects of image reconstruction algorithms on topographic characteristics, diagnostic performance and clinical correlation of metabolic brain networks in Parkinson's disease.

  2018cites this paper
• The effect of intravitreal cholinergic drugs on motor control

  2018cites this paper
• Network imaging biomarkers: insights and clinical applications in Parkinson's disease.

  2018cites this paper
• Abnormal metabolic brain network associated with Parkinson’s disease: replication on a new European sample

  2017cites this paper
• Levodopa-induced abnormal involuntary movements correlate with altered permeability of the blood-brain-barrier in the basal ganglia

  2017cites this paper
• Transplantation in the nonhuman primate MPTP model of Parkinson's disease: update and perspectives

  2017influential citation
• Network Structure and Function in Parkinson’s Disease

  2017influential citation
• Reverse Translation in Parkinson Disease

  2016cites this paper
• Abnormal Metabolic Brain Networks in a Nonhuman Primate Model of Parkinsonism

  2012cites this paper