Ubiquitylation of epsilon-COP by PIRH2 and regulation of the secretion of PSA.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Molecular and Cellular Biochemistry

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 17721809
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Human PIRH2 Enhances Androgen Receptor Signaling through Inhibition of Histone Deacetylase 1 and Is Overexpressed in Prostate Cancer

  2006influential reference
• Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP.

  2006cited by this paper
• Hormone refractory prostate cancer (HRPC): present and future approaches of therapy.

  2006cited by this paper
• A new human gene hNTKL-BP1 interacts with hPirh2.

  2005cited by this paper
• The Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphatase.

  2005cited by this paper
• ARFGAP1 plays a central role in coupling COPI cargo sorting with vesicle formation

  2005cited by this paper
• Control of Human PIRH2 Protein Stability

  2004cited by this paper
• Mechanisms of androgen-refractory prostate cancer.

  2004cited by this paper
• Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer.

  2004cited by this paper
• Androgen receptor involvement in the progression of prostate cancer.

  2003cited by this paper
• Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation.

  2003cited by this paper
• Identification and characterization of a ligand-regulated nuclear export signal in androgen receptor.

  2003cited by this paper
• Faculty Opinions recommendation of Sorting of Golgi resident proteins into different subpopulations of COPI vesicles: a role for ArfGAP1.

  2002cited by this paper
• Molecular biology of the androgen receptor.

  2002cited by this paper
• Tip60 and Histone Deacetylase 1 Regulate Androgen Receptor Activity through Changes to the Acetylation Status of the Receptor*

  2002cited by this paper
• Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity.

  2002cited by this paper
• U Box Proteins as a New Family of Ubiquitin-Protein Ligases*

  2001cited by this paper
• Sorting of Golgi resident proteins into different subpopulations of COPI vesicles

  2001cited by this paper
• A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy.

  2001cited by this paper
• Different expression of androgen receptor coactivators in human prostate.

  2001cited by this paper
• Expression of androgen receptor coregulatory proteins in prostate cancer and stromal‐cell culture models

  2000cited by this paper
• RING finger proteins: mediators of ubiquitin ligase activity.

  2000cited by this paper
• RING for destruction?

  2000cited by this paper
• Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cells.

  2000cited by this paper
• RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination.

  1999cited by this paper
• Phylogenetic Analysis of Components of the Eukaryotic Vesicle Transport System Reveals a Common Origin of Adaptor Protein Complexes 1, 2, and 3 and the F Subcomplex of the Coatomer COPI

  1999cited by this paper
• The ubiquitin system.

  1998cited by this paper
• Two Androgen Response Regions Cooperate in Steroid Hormone Regulated Activity of the Prostate-specific Antigen Promoter (*)

  1996cited by this paper
• A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase.

  1995cited by this paper
• Protein ubiquitination involving an E1–E2–E3 enzyme ubiquitin thioester cascade

  1995cited by this paper
• Prostate specific antigen and gleason grade: an immunohistochemical study of prostate cancer.

  1994cited by this paper
• Mechanisms of intracellular protein transport

  1994cited by this paper
• Stepwise assembly of functionally active transport vesicles.

  1993cited by this paper
• Measurement of prostate-specific antigen in serum as a screening test for prostate cancer.

  1991cited by this paper
• The promoter of the prostate-specific antigen gene contains a functional androgen responsive element.

  1991cited by this paper
• Prostate specific antigen: a critical assessment of the most useful tumor marker for adenocarcinoma of the prostate.

  1991cited by this paper
• Antipeptide antibodies to two distinct regions of the androgen receptor localize the receptor protein to the nuclei of target cells in the rat and human prostate.

  1990cited by this paper
• Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown.

  1983cited by this paper
• Flutamide. Mechanism of action of a new nonsteroidal antiandrogen.

  1976cited by this paper

• Post-Translational Modifications That Drive Prostate Cancer Progression

  2021cites this paper
• Directing Traffic: Regulation of COPI Transport by Post-translational Modifications

  2019cites this paper
• High expression of P53-induced Ring-h2 protein is associated with poor prognosis in clear cell renal cell carcinoma.

  2013cites this paper
• The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover

  2013cites this paper
• Pirh2 RING‐finger E3 ubiquitin ligase: Its role in tumorigenesis and cancer therapy

  2012cites this paper
• Ubiquitin E3 ligases controlling p53 stability

  2012cites this paper
• Pirh 2 RING-finger E 3 ubiquitin ligase : Its role in tumorigenesis and cancer therapy

  2012cites this paper
• A novel oncoprotein Pirh2: rising from the shadow of MDM2

  2011cites this paper
• The p73 Tumor Suppressor Is Targeted by Pirh2 RING Finger E3 Ubiquitin Ligase for the Proteasome-dependent Degradation*

  2011cites this paper
• Porcine circovirus type 2 ORF 3 protein competes with P 53 in binding to Pirh 2 and mediates the deregulation of P 53 homeostasis

  2010cites this paper
• Characterization of the E3 Ubiquitin Ligase Pirh2

  2010influential citation
• Porcine circovirus type 2 ORF3 protein competes with p53 in binding to Pirh2 and mediates the deregulation of p53 homeostasis.

  2010cites this paper
• High expression of Pirh2, an E3 ligase for p27, is associated with low expression of p27 and poor prognosis in head and neck cancers

  2009cites this paper
• Regulation of p53: TRIM24 enters the RING

  2009cites this paper
• Measles virus interaction with host cells and impact on innate immunity.

  2009cites this paper
• Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit.

  2008cites this paper