Action of pepsin on cationic synthetic substrates.

No abstract is available for this paper.

• Publication year

  1969

• Venue

  Biochemistry

• Publication date

  1969-02-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/BI00830A017PMID 4893576
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The substrate binding site of pepsin.

  1968cited by this paper
• Kinetics of the hydrolysis of synthetic substrates by pepsin and by acetyl-pepsin.

  1968cited by this paper
• The catalytic and regulatory properties of enzymes.

  1968cited by this paper
• The inhibition of pepsin action.

  1968cited by this paper
• Facilitated proton transfer in enzyme catalysis. It may have a crucial role in determining the efficiency and specificity of enzymes.

  1968cited by this paper
• The effect of modifiers on the hydrolysis of esters and peptides by carboxypeptidase A.

  1968cited by this paper
• The pH dependence of the pepsin-catalyzed hydrolysis of N-acetyl-L-phenylalanyl-L-3,5-dibromotyrosine.

  1967cited by this paper
• The structure of carboxypepidase A. V. Studies of enzyme-substrate and enzyme-inhibitor complexes at 6 A resolution.

  1967cited by this paper
• On the size of the active site in proteases. I. Papain.

  1967cited by this paper
• The structure of carboxypeptidase a, vi. Some results at 2.0-a resolution, and the complex with glycyl-tyrosine at 2.8-a resolution.

  1967cited by this paper
• Studies on the specificity of pepsin.

  1967cited by this paper
• Crystallographic studies of the activity of hen egg-white lysozyme

  1967cited by this paper
• A computer program for fitting data to the Michaelis-Menten equation.

  1967cited by this paper
• SPECIFIC INACTIVATION OF PEPSIN BY A DIAZO KETONE*

  1966cited by this paper
• The alpha-chymotryptic ydrolysis of glycine esters.

  1966cited by this paper
• New synthetic substrates for pepsin.

  1966cited by this paper
• Pepsin from pepsinogen. Preparation and properties.

  1966cited by this paper
• Inactivation of pepsin by diphenyldiazomethane.

  1965cited by this paper
• THE PRIMARY SPECIFICITY OF ALPHA-CHYMOTRYPSIN. ACYLATED AMINO ACID ESTERS WITH NORMAL ALKYL SIDE CHAINS.

  1965cited by this paper
• The alpha-chymotrypsin catalyzed hydrolysis of a series of acylated glycine methyl esters.

  1963cited by this paper
• An interpretation of the kinetic behavior of model substrates of alpha-chymotrypsin.

  1961cited by this paper
• Pepsincatalysed transpeptidation of the amino-transfer type.

  1959cited by this paper
• Fatty acid esters as substrates for trypsin and chymotrypsin.

  1957cited by this paper
• The kinetics of the action of pepsin on synthetic substrates.

  1954cited by this paper
• Steric inhibition of amide resonance and its possible significance in enzyme action.

  1953cited by this paper
• The determination of enzyme inhibitor constants.

  1953cited by this paper
• The pleated sheet, a new layer configuration of polypeptide chains.

  1951cited by this paper
• New synthetic substrates for pepsin.

  1951cited by this paper

• CHEMICAL MODIFICATIONS OF THE SUBTILISINS WITH SPECIAL REFERENCE TO THE BINDING OF LARGE SUBSTRATES

  2008cites this paper
• NMR study of the inhibition of pepsin by glyoxal inhibitors: mechanism of tetrahedral intermediate stabilization by the aspartyl proteases.

  2007cites this paper
• The mechanism of the catalytic action of pepsin and related acid proteinases.

  2006cites this paper
• A History Of Pepsin And Related Enzymes

  2002cites this paper
• Probing the mechanism of nitrogen transfer in Escherichia coli asparagine synthetase by using heavy atom isotope effects.

  1996cites this paper
• A Sensitive Fluorometric Assay for Activity of Pepsin

  1993cites this paper
• Inhibition of porcine pepsin by two substrate analogues containing statine. The effect of histidine at the P2 subsite on the inhibition of aspartic proteinases.

  1988cites this paper
• Chapter 1 Aspartyl proteinases

  1987cites this paper
• Stereochemical analysis of peptide bond hydrolysis catalyzed by the aspartic proteinase penicillopepsin.

  1985cites this paper
• Hydrolysis of the synthetic chromophoric hexapeptide Leu-Ser-Phe(NO2)-Nle-Ala-Leu-OMe catalyzed by bovine pepsin A. Dependence on pH and effect of enzyme phosphorylation level.

  1984cites this paper
• Effect of pH on the activities of penicillopepsin and Rhizopus pepsin and a proposal for the productive substrate binding mode in penicillopepsin.

  1984cites this paper
• Kinetics of the action of thermolysin on peptide substrates.

  1978cites this paper
• Specificity and mechanism of pepsin action on synthetic substrates.

  1977cites this paper
• Effects of secondary binding by activator and inhibitor peptides on covalent intermediates of pig pepsin.

  1976cites this paper
• Chemical modifications of the subtilisins with special reference to the binding of large substrates. A review

  1976cites this paper
• Large peptides of bovine and guinea pig myelin basic proteins produced by limited peptic hydrolysis.

  1975cites this paper
• Fluorescence studies on the active sites of porcine pepsin and Rhizopus-pepsin.

  1975cites this paper
• Interaction of 9-peptidylaminoacridines with proteins and nucleic acids.

  1974cites this paper
• Inhibition of the Cathepsin D-Type Proteinase of Macrophages by Pepstatin, a Specific Pepsin Inhibitor, and Other Substances

  1973cites this paper
• Peptide Synthesis and the Specificity of Proteinases

  1973cites this paper
• N-methyl-2-anilinonaphthalene-6-sulfonyl peptides as fluorescent probes for pepsin-substrate interaction.

  1973cites this paper
• The rennin catalyzed hydrolysis of a tripeptide. Evidence for catalysis by two carboxyl groups.

  1972cites this paper
• Fluorescence studies on the interaction of pepsin with its substrates.

  1972cites this paper
• Gel filtration studies on the binding of peptides to pepsin.

  1972cites this paper
• Catalytic configurations.

  1972cites this paper
• Exhaustive Proteolysis of Derivatives of Lysozyme

  1971cites this paper
• Fluorescent probes for conformational states of proteins. IV. The pepsinogen-pepsin conversion.

  1971cites this paper
• Pepsinogens, pepsins, and pepsin inhibitors.

  1971cites this paper
• Directional character of proton transfer in enzyme catalysis.

  1970cites this paper
• Effect of secondary enzyme-substrate interactions on the cleavage of synthetic peptides by pepsin.

  1970cites this paper
• The specificity and mechanism of pepsin action.

  1970cites this paper
• Secondary enzyme-substrate interactions and the specificity of pepsin.

  1970cites this paper
• [20] The porcine pepsins and pepsinogens

  1970cites this paper
• Specificity and Mechanism of Pepsin Action

  1970cites this paper
• The side-chain specificity of pepsin.

  1969cites this paper
• Pyridyl esters of peptides as synthetic substrates of pepsin.

  1969cites this paper
• On the mechanism of pepsin action.

  1961cites this paper