Relationship of brown adipose tissue perfusion and function: a study through β2-adrenoreceptor stimulation.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of applied physiology

• Publication date

  2016-04-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/japplphysiol.00634.2015PMID 26823340PMCID PMC4835910
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Functional brown adipose tissue limits cardiomyocyte injury and adverse remodeling in catecholamine-induced cardiomyopathy.

  2015cited by this paper
• Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis.

  2015cited by this paper
• Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans

  2014cited by this paper
• Glucose uptake in brown fat cells is dependent on mTOR complex 2–promoted GLUT1 translocation

  2014cited by this paper
• Vascular rarefaction mediates whitening of brown fat in obesity.

  2014cited by this paper
• Beta2-adrenoceptor stimulation has no effect on skeletal muscle glucose uptake

  2014cited by this paper
• Brown fat in humans: consensus points and experimental guidelines.

  2014cited by this paper
• Brown adipose tissue blood flow and mass in obesity: a contrast ultrasound study in mice.

  2013influential reference
• Quantification of Human and Rodent Brown Adipose Tissue Function Using 99mTc-Methoxyisobutylisonitrile SPECT/CT and 18F-FDG PET/CT

  2013cited by this paper
• 15O PET Measurement of Blood Flow and Oxygen Consumption in Cold-Activated Human Brown Fat

  2013cited by this paper
• Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.

  2013cited by this paper
• In Vivo Noninvasive Characterization of Brown Adipose Tissue Blood Flow by Contrast Ultrasound in Mice

  2012influential reference
• Brown adipose tissue growth and development: significance and nutritional regulation.

  2011cited by this paper
• Different metabolic responses of human brown adipose tissue to activation by cold and insulin.

  2011cited by this paper
• Assessment of Oxidative Metabolism in Brown Fat Using PET Imaging

  2011cited by this paper
• The physiological regulation of glucose flux into muscle in vivo

  2011cited by this paper
• Validation of noninvasive measurements of cardiac output in mice using echocardiography.

  2011cited by this paper
• Sympathetic and sensory innervation of brown adipose tissue

  2010cited by this paper
• Determinants of brown adipocyte development and thermogenesis

  2010cited by this paper
• Identification and importance of brown adipose tissue in adult humans.

  2009cited by this paper
• The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action

  2009cited by this paper
• β2‐Adrenoceptor agonists alleviate neuropathic allodynia in mice after chronic treatment

  2009cited by this paper
• The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue

  2009cited by this paper
• Cold-activated brown adipose tissue in healthy men.

  2009cited by this paper
• Impaired microvascular perfusion: a consequence of vascular dysfunction and a potential cause of insulin resistance in muscle.

  2008cited by this paper
• The discovery of drugs for obesity, the metabolic effects of leptin and variable receptor pharmacology: perspectives from β3-adrenoceptor agonists

  2008cited by this paper
• Unexpected evidence for active brown adipose tissue in adult humans.

  2007cited by this paper
• Beta3-adrenergic receptors stimulate glucose uptake in brown adipocytes by two mechanisms independently of glucose transporter 4 translocation.

  2006cited by this paper
• Uncoupling protein 1 is necessary for norepinephrine-induced glucose utilization in brown adipose tissue.

  2005cited by this paper
• Intravenous salbutamol: too much of a good thing?

  2005cited by this paper
• Brown adipose tissue: function and physiological significance.

  2004cited by this paper
• Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

  2002cited by this paper
• βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance

  2002cited by this paper
• β-Agonists and metabolism

  2002cited by this paper
• beta-Agonists and metabolism.

  2002cited by this paper
• Faculty Opinions recommendation of betaAR signaling required for diet-induced thermogenesis and obesity resistance.

  2002cited by this paper
• Thermogenic Responses in Brown Fat Cells Are Fully UCP1-dependent

  2000cited by this paper
• Differential adrenergic regulation of the gene expression of the beta-adrenoceptor subtypes beta1, beta2 and beta3 in brown adipocytes.

  2000cited by this paper
• Differential adrenergic regulation of the gene expression of the β-adrenoceptor subtypes β1, β2 and β3 in brown adipocytes

  2000cited by this paper
• The beta2-adrenergic agonist salbutamol is a potent suppressor of established collagen-induced arthritis: mechanisms of action.

  1999cited by this paper
• Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion.

  1998cited by this paper
• Respective degree of expression of β1, β2‐ and β3‐adrenoceptors in human brown and white adipose tissues

  1996cited by this paper
• Respective degree of expression of beta 1-, beta 2- and beta 3-adrenoceptors in human brown and white adipose tissues.

  1996cited by this paper
• Guide for the Care and Use of Laboratory Animals

  1996cited by this paper
• Insulin-mediated skeletal muscle vasodilation contributes to both insulin sensitivity and responsiveness in lean humans.

  1995cited by this paper
• Involvement of nitric oxide in noradrenaline-induced increase in blood flow through brown adipose tissue.

  1994cited by this paper
• Coexisting beta-adrenoceptor subtypes: significance for thermogenic process in brown fat cells.

  1994cited by this paper
• Skeletal muscle blood flow independently modulates insulin-mediated glucose uptake.

  1994cited by this paper
• Single-dose and steady-state effects of controlled-release salbutamol on drug level and airflow obstruction in patients with asthma.

  1992cited by this paper
• Selective stimulation of glucagon secretion by β2‐adrenoceptors in isolated islets of Langerhans of the rat

  1991cited by this paper
• The selectivity of xamoterol, prenalterol, and salbutamol as assessed by their effects in the presence and absence of ICI 118,551.

  1990cited by this paper
• Selectivity of xamoterol, prenalterol and salbutamol as assessed by their effects in the presence and absence of ICI 118 551.

  1988cited by this paper
• Pharmacokinetics of intravenous and oral salbutamol and its sulphate conjugate.

  1986cited by this paper
• Norepinephrine-induced beta 1-adrenergic peripheral vasodilation in conscious dogs.

  1985cited by this paper
• The characterization and energetic potential of brown adipose tissue in man.

  1985cited by this paper
• Influence of noradrenaline on blood flow to brown adipose tissue in rats exhibiting diet-induced thermogenesis

  1981cited by this paper
• Tissue distribution of cold-induced thermogenesis in conscious warm- or cold-acclimated rats reevaluated from changes in tissue blood flow: the dominant role of brown adipose tissue in the replacement of shivering by nonshivering thermogenesis.

  1979cited by this paper
• Nonshivering thermogenesis in the rat. II. Measurements of blood flow with microspheres point to brown adipose tissue as the dominant site of the calorigenesis induced by noradrenaline.

  1978cited by this paper
• Effects of Norepinephrine on Coronary Circulation and Left Ventricular Dynamics in the Conscious Dog

  1974cited by this paper

• Glucose sensing and homeostasis by adipocyte GPCR

  2025cites this paper
• Exploring receptors for pro-resolving and non-pro-resolving mediators as therapeutic targets for sarcopenia.

  2025cites this paper
• Genetic evidence for involvement of β2-adrenergic receptor in brown adipose tissue thermogenesis in humans

  2024cites this paper
• The role of the heart in the evolution of aerobic performance.

  2024cites this paper
• Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans.

  2023cites this paper
• Stimulation of the beta-2-adrenergic receptor with salbutamol activates human brown adipose tissue

  2023cites this paper
• The β2-adrenergic receptor in the apical membrane of intestinal enterocytes senses sugars to stimulate glucose uptake from the gut

  2023cites this paper
• Regulatory roles of G-protein coupled receptors in adipose tissue metabolism and their therapeutic potential

  2021cites this paper
• Magnetic Resonance Imaging Techniques for Brown Adipose Tissue Detection

  2020cites this paper
• Functional characterization of human brown adipose tissue metabolism.

  2020cites this paper
• Brain-Sparing Sympathofacilitators Mitigate Obesity without Adverse Cardiovascular Effects

  2020influential citation
• Contribution of perfusion to the 11C‐acetate signal in brown adipose tissue assessed by DCE‐MRI and 68Ga‐DOTA PET in a rat model

  2020cites this paper
• Multispectral Optoacoustic Tomography of Brown Adipose Tissue.

  2019cites this paper
• Ablation of adipocyte creatine transport impairs thermogenesis and causes diet-induced obesity

  2019cites this paper
• Brown Adipose Tissue

  2019cites this paper
• Effects of aerobic exercise on the inflammatory cytokine profile and expression of lipolytic and thermogenic genes in &bgr;1‐AR−/− mice adipose tissue

  2019cites this paper
• Adrenoceptors in white, brown, and brite adipocytes

  2019cites this paper
• Beta2-adrenergic stimulation increases energy expenditure at rest, but not during submaximal exercise in active overweight men

  2017cites this paper
• Inhibition of Intracellular Triglyceride Lipolysis Suppresses Cold-Induced Brown Adipose Tissue Metabolism and Increases Shivering in Humans.

  2017influential citation
• The role of BAT in cardiometabolic disorders and aging.

  2016cites this paper