Effects of codon modification on human BMP2 gene expression in tobacco plants

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Plant Cell Reports

• Publication date

  2006-02-21

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00299-006-0133-6PMID 16491379
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2003influential reference
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