The use of modified hemoglobin as an oxygen carrying blood substitute.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Transfusion Medicine Reviews

• Publication date

  1989-06-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0887-7963(89)70081-XPMID 2520555
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In vivo evaluation of a pyridoxylated-hemoglobin-polyoxyethylene conjugate.

  2009cited by this paper
• A new resuscitation fluid "stabilized hemoglobin" preparation and characteristics.

  1989cited by this paper
• (Pyridoxalated Hemoglobin)-(Polyoxyethylene) Conjugate Solution as Blood Substitute for Normothermic Whole Body Rinse-Out

  1988cited by this paper
• An overview of the chemical modification of stroma free hemoglobin.

  1988cited by this paper
• Virus inactivation in hemoglobin solutions by heat.

  1988cited by this paper
• Characteristics of polymerized pyridoxylated hemoglobin.

  1988cited by this paper
• Quality control of hemoglobin-based blood substitutes.

  1988cited by this paper
• Conjugated Hemoglobin: Rightshifted Dextran-Hemoglobin as Blood Substitute

  1988cited by this paper
• An overview of the chemical modification of stroma free hemoglobin.

  1988cited by this paper
• Preparation of virus-free pyridoxylated hemoglobin from the blood of HBV or HTLV-I healthy carriers.

  1988cited by this paper
• Liposome-encapsulated hemoglobin: oxygen binding properties and respiratory function.

  1988cited by this paper
• Removal of bacteria from blood by charcoal hemoperfusion.

  1988cited by this paper
• Kinetics of Ligand Binding to An αα-Crosslinked Hemoglobin

  1988cited by this paper
• Factors influencing the in vitro stability of artificial red blood cells based on hemoglobin-containing liposomes.

  1988cited by this paper
• Red blood cell substitutes: microencapsulated hemoglobin and cross-linked hemoglobin including pyridoxylated polyhemoglobin & conjugated hemoglobin.

  1988cited by this paper
• Rightshifted dextran-hemoglobin as blood substitute.

  1988cited by this paper
• Pyridoxylated-polyhemoglobin solution: a low viscosity oxygen-delivering blood replacement fluid with normal oncotic pressure and long-term storage feasibility.

  1988cited by this paper
• Metabolism, Distribution, and Excretion of HbXL: A Nondissociating Interdimerically Crosslinked Hemoglobin with Exceptional Oxygen Offloading Capability

  1988cited by this paper
• Hemodynamic effects of exchange transfusions with liposome-encapsulated hemoglobin.

  1988cited by this paper
• Quality control of hemoglobin-based blood substitutes.

  1988cited by this paper
• Chronotropic Effect of Stroma-Free Hemoglobin and Polyhemoglobin on Cultured Myocardiocytes Derived from Newborn Rats

  1988cited by this paper
• Hemoglobin preparations for perfusion & infusion problems of large-scale production.

  1988cited by this paper
• Virus removal or inactivation in hemoglobin solutions by ultrafiltration or detergent/solvent treatment.

  1988cited by this paper
• Effects of stroma-free hemoglobin solutions on isolated perfused rabbit hearts and isolated perfused rat kidneys.

  1988cited by this paper
• Hemoglobin: a lifesaver and an oxidant. How to tip the balance.

  1988cited by this paper
• Mechanisms of toxicity of hemoglobin solutions.

  1988cited by this paper
• Liposome/heme as a totally synthetic oxygen carrier.

  1988cited by this paper
• Immunological and systemic effects of transfusions in rats using pyridoxylated hemoglobin and polyhemoglobin from homologous and heterogeneous sources.

  1988cited by this paper
• Effects of Partial and Total Isovolemic Exchange Transfusion in Fully Conscious Rats Using Pyridoxylated Polyhemoglobin Solution as a Colloidal Oxygen‐Delivering Blood Replacement Fluid 1

  1987cited by this paper
• Pyridoxalated heterogenous and homologous polyhemoglobin and hemoglobin: systemic effects of replacement transfusion in rats previously received immunizing doses.

  1987cited by this paper
• Reduced coronary vasoconstrictor activity of hemoglobin solutions purified by ATP-agarose affinity chromatography.

  1987cited by this paper
• Serum Antibody Titers in Rats Receiving Repeated Small Subcutaneous Injections of Hemoglobin or Polyhemoglobin: A Preliminary Report

  1986cited by this paper
• Synthesis and evaluation of a prototypal artificial red cell.

  1985cited by this paper
• Effect of pyridoxalated stabilized stroma-free hemoglobin solution on the clearance of intravascular lipid by the reticuloendothelial system.

  1985cited by this paper
• Hemodynamics and Oxygen Transport after Partial and Total Blood Exchange with Pyridoxalated Polyhemoglobin in Dogs

  1985cited by this paper
• Pyridoxylated polyhemoglobin as a red cell substitute for resuscitation of lethal hemorrhagic shock in conscious rats.

  1985cited by this paper
• Preparation and in vitro characteristics of a blood substitute based on pyridoxylated polyhemoglobin.

  1984cited by this paper
• Separation of glyoxylated hemoglobin with varying oxygen affinity by polyanion fast protein liquid chromatography.

  1984cited by this paper
• Polymerized pyridoxylated hemoglobin: a red cell substitute with normal oxygen capacity.

  1984cited by this paper
• Hemoglobin solution--from tetramer to polymer.

  1984cited by this paper
• Encapsulation of hemoglobin in phospholipid vesicles: preparation and properties of a red cell surrogate.

  1984cited by this paper
• Encapsulation of hemoglobin in phospholipid vesicles: preparation and properties of a red cell surrogate.

  1984cited by this paper
• A pyridoxylated Polymerized Hemoglobin Solution as Oxygen Carrying Substitute

  1983cited by this paper
• Preparation and in vitro characteristics of polymerized pyridoxylated hemoglobin

  1983cited by this paper
• In vivo assessment of pyridoxylated crosslinked polyhemoglobin as an artificial red cell substitute in rats.

  1983cited by this paper
• In vivo assessment of pyridoxylated crosslinked polyhemoglobin as an artificial red cell substitute in rats.

  1983cited by this paper
• Development of a bovine stroma-free hemoglobin solution as a blood substitute.

  1983cited by this paper
• Blood exchange with pyridoxalated and polymerized hemoglobin solution.

  1982cited by this paper
• Cross-linked Stroma-free Polyhemoglobin as a Potential Blood Substitute

  1982cited by this paper
• Modification of human hemoglobin with polyethylene glycol : a new candidate for blood substitute.

  1980cited by this paper
• Artificial red blood cells.

  1980cited by this paper
• The development of haemoglobin preparations for various indications.

  1980cited by this paper
• Synthetic erythrocytes from lipid encapsulated hemoglobin.

  1980cited by this paper
• Intravascular persistence and oxygen delivery of pyridoxalated, stroma-free hemoglobin during gradations of hypotension.

  1979cited by this paper
• A clinical safety trial of stroma‐free hemoglobin

  1978cited by this paper
• Characteristics of stroma-free hemoglobin prepared by crystallization.

  1977cited by this paper
• Transport of oxygen and carbon dioxide by hemoglobin-saline solution in the red cell-free primate.

  1976cited by this paper
• Soluble dextran-hemoglobin complex as a potential blood substitute.

  1976cited by this paper
• Hemoglobin covalently bridged across the polyphoshate binding site.

  1975cited by this paper
• THE RENAL HANDLING OF HEMOGLOBIN

  1969cited by this paper
• The renal handling of hemoglobin.

  1968cited by this paper
• EVALUATION OF A STROMA-FREE HEMOGLOBIN SOLUTION FOR USE AS A PLASMA EXPANDER

  1967cited by this paper
• Semipermeable aqueous microcapsules. I. Preparation and properties.

  1966cited by this paper
• Semipermeable Microcapsules

  1964cited by this paper

• De los acarreadores de oxígeno (HbCO) a los polimerosomas. Una mirada a las células artificiales

  2015cites this paper
• 2001 Lemieux Award Lecture Organic chemistry and hemoglobin: Benefits from controlled alteration

  2002cites this paper
• Care of Injured Patients in the Field, During Transport, and in the Emergency Department

  2000cites this paper
• Systemic hemodynamic and hepatic microvascular responses to a 33% blood volume exchange with whole blood, stroma-free hemoglobin, and oxypolyhemoglobin solutions.

  1993cites this paper
• Protein Engineering: Modified Hemoglobin as a Blood Substitute

  1992cites this paper
• PROTEIN ENGINEERING : MODIFIZIERTES HAMOGLOBIN ALS BLUTERSATZSTOFF

  1992cites this paper
• Artificial blood.

  1991cites this paper
• The health strategy and the hole at the centre.

  1991cites this paper
• Biotechnological and Medical Applications Based on Immobilization of Hepatocytes, Microorganisms, or Enzyme Systems by Microencapsulation in Artificial Cells a

  1990cites this paper