Cocaine represses protein phosphatase-1Cβ through DNA methylation and Methyl-CpG Binding Protein-2 recruitment in adult rat brain.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Neuropharmacology

• Publication date

  2013-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.neuropharm.2013.05.005PMID 23688924
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Post‐training cocaine exposure facilitates spatial memory consolidation in C57BL/6 mice

  2012cited by this paper
• MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system

  2012cited by this paper
• What We Know and Would Like to Know about CDKL5 and Its Involvement in Epileptic Encephalopathy

  2012cited by this paper
• Cognitive enhancers for facilitating drug cue extinction: insights from animal models.

  2011cited by this paper
• The epigenetic landscape of addiction

  2011cited by this paper
• CpG islands and the regulation of transcription.

  2011cited by this paper
• 5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

  2011cited by this paper
• Cocaine self-administration alters the expression of chromatin-remodelling proteins; modulation by histone deacetylase inhibition

  2011cited by this paper
• Epigenetic regulation of gene expression in physiological and pathological brain processes.

  2011cited by this paper
• Epigenetics and lifestyle.

  2011cited by this paper
• Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond

  2011cited by this paper
• Adult Neural Function Requires MeCP2

  2011cited by this paper
• Transcriptional and epigenetic mechanisms of addiction

  2011cited by this paper
• Methylation on the mind

  2011cited by this paper
• Different chronic cocaine administration protocols induce changes on dentate gyrus plasticity and hippocampal dependent behavior

  2010cited by this paper
• MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212

  2010influential reference
• Cocaine causes memory and learning impairments in rats: involvement of nuclear factor kappa B and oxidative stress, and prevention by topiramate

  2010cited by this paper
• Inhibition of histone deacetylases in rats self‐administering cocaine regulates lissencephaly gene‐1 and reelin gene expression, as revealed by microarray technique

  2010cited by this paper
• Cortical DNA methylation maintains remote memory

  2010cited by this paper
• DNA Methylation Regulates Cocaine-Induced Behavioral Sensitization in Mice

  2010influential reference
• MeCP2 and drug addiction

  2010cited by this paper
• MeCP2 in the Nucleus Accumbens Contributes to Neural and Behavioral Responses to Psychostimulants

  2010cited by this paper
• CDKL5 is a brain MeCP2 target gene regulated by DNA methylation.

  2010cited by this paper
• Protein phosphatase 1-dependent transcriptional programs for long-term memory and plasticity.

  2010cited by this paper
• Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

  2010cited by this paper
• Effect of 5-aza-2-deoxycytidine microinjecting into hippocampus and prelimbic cortex on acquisition and retrieval of cocaine-induced place preference in C57BL/6 mice.

  2010cited by this paper
• Confining euchromatin/heterochromatin territory: jumonji crosses the line.

  2010cited by this paper
• Binding of the Rett syndrome protein, MeCP2, to methylated and unmethylated DNA and chromatin

  2010cited by this paper
• Unique physical properties and interactions of the domains of methylated DNA binding protein 2.

  2010cited by this paper
• Dnmt3a: addiction's molecular forget-me-not?

  2010cited by this paper
• From promiscuity to precision: protein phosphatases get a makeover.

  2009cited by this paper
• The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits.

  2008cited by this paper
• Histone Deacetylase Inhibitors Decrease Cocaine But Not Sucrose Self-Administration in Rats

  2008cited by this paper
• Covalent modification of DNA regulates memory formation.

  2007cited by this paper
• Emerging roles of nuclear protein phosphatases

  2007cited by this paper
• Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome

  2006cited by this paper
• Learning and Memory and Synaptic Plasticity Are Impaired in a Mouse Model of Rett Syndrome

  2006cited by this paper
• Mecp2 deficiency is associated with learning and cognitive deficits and altered gene activity in the hippocampal region of mice.

  2006cited by this paper
• Fluoxetine and Cocaine Induce the Epigenetic Factors MeCP2 and MBD1 in Adult Rat Brain

  2006cited by this paper
• Phosphorylation of DARPP-32 at Threonine-34 is Required for Cocaine Action

  2006cited by this paper
• Impaired Bidirectional Synaptic Plasticity and Procedural Memory Formation in Striatum-Specific cAMP Response Element-Binding Protein-Deficient Mice

  2006cited by this paper
• Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome.

  2005cited by this paper
• Addiction: a disease of learning and memory.

  2005cited by this paper
• Eukaryotic cytosine methyltransferases.

  2005cited by this paper
• Repeated Cocaine Administration Decreases Calcineurin (PP2B) but Enhances DARPP-32 Modulation of Sodium Currents in Rat Nucleus Accumbens Neurons

  2005cited by this paper
• Epigenetic Mechanisms and Gene Networks in the Nervous System

  2005cited by this paper
• Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).

  2004cited by this paper
• Epigenetics in human disease and prospects for epigenetic therapy

  2004cited by this paper
• DARPP-32: an integrator of neurotransmission.

  2004cited by this paper
• Mutations of CDKL5 cause a severe neurodevelopmental disorder with infantile spasms and mental retardation.

  2004cited by this paper
• MeCP2 Repression Goes Nonglobal

  2003cited by this paper
• Molecular biology. MeCP2 repression goes nonglobal.

  2003cited by this paper
• Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3.

  2002influential reference
• Dopamine enhancement of NMDA currents in dissociated medium-sized striatal neurons: role of D1 receptors and DARPP-32.

  2002cited by this paper
• Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1.

  2002cited by this paper
• Protein phosphatase 1 is a molecular constraint on learning and memory

  2002cited by this paper
• Inducible and reversible enhancement of learning, memory, and long-term potentiation by genetic inhibition of calcineurin.

  2001cited by this paper
• Multiple Regulatory Elements in the Murine Stromelysin-3 Promoter

  2000cited by this paper
• Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

  1999cited by this paper
• Protein phosphatase 1 modulation of neostriatal AMPA channels: regulation by DARPP–32 and spinophilin

  1999cited by this paper
• Differential cellular and subcellular localization of protein phosphatase 1 isoforms in brain

  1999cited by this paper
• Neuronal and behavioural abnormalities in striatal function in DARPP‐32‐mutant mice

  1999cited by this paper
• Conditioning factors in drug abuse: can they explain compulsion?

  1998cited by this paper
• A Dopamine/D1 Receptor/Protein Kinase A/Dopamine- and cAMP-Regulated Phosphoprotein (Mr 32 kDa)/Protein Phosphatase-1 Pathway Regulates Dephosphorylation of the NMDA Receptor

  1998cited by this paper
• Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

  1998cited by this paper
• Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

  1998cited by this paper
• Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines.

  1997cited by this paper
• Neurabin: A Novel Neural Tissue–specific Actin Filament–binding Protein Involved in Neurite Formation

  1997cited by this paper
• Differential expression of protein phosphatase 1 isoforms in mammalian brain

  1995cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper

• Cocaine‐Induced Changes in the BRD4 Interactome Identifies Casein Kinase 1 Epsilon as a Therapeutic Target

  2026cites this paper
• Research progress of DNA methylation on the regulation of substance use disorders and the mechanisms

  2025cites this paper
• Cocaine-Induced Cardiovascular and Immune Dysfunction: Emerging Mechanisms.

  2025cites this paper
• The DNA methylation enzymatic machinery in substance use disorders: a systematic review

  2025cites this paper
• The epigenetically regulated PP1α expression by KDM1A may contribute to oxycodone conditioned place preference in mice.

  2024cites this paper
• Substance-Induced Psychiatric Disorders, Epigenetic and Microbiome Alterations, and Potential for Therapeutic Interventions

  2024cites this paper
• POMC-specific knockdown of MeCP2 leads to adverse phenotypes in mice chronically exposed to high fat diet.

  2024cites this paper
• Drug addiction and treatment: An epigenetic perspective.

  2023cites this paper
• PP1 catalytic isoforms are differentially expressed and regulated in human prostate cancer.

  2022cites this paper
• Gnas Promoter Hypermethylation in the Basolateral Amygdala Regulates Reconsolidation of Morphine Reward Memory in Rats

  2022cites this paper
• Methylation of TET2 Promoter Is Associated with Global Hypomethylation and Hypohydroxymethylation in Peripheral Blood Mononuclear Cells of Systemic Lupus Erythematosus Patients

  2022cites this paper
• THE TRANSLATIONAL GENETICS OF ADHD AND RELATED PHENOTYPES IN MODEL ORGANISMS.

  2022cites this paper
• Convergent actions of stress and stimulants via epigenetic regulation of neural circuitry.

  2022cites this paper
• Genomics and epigenomics of addiction

  2021cites this paper
• Epigenetic and Genetic Factors Associated With Opioid Use Disorder: Are These Relevant to African American Populations

  2021cites this paper
• Epigenetic Regulation of Circadian Clocks and Its Involvement in Drug Addiction

  2021cites this paper
• AddictGene: An integrated knowledge base for differentially expressed genes associated with addictive substance

  2021cites this paper
• Rhythmic Regulation of DNA Methylation Factors and Core-Clock Genes in Brain Structures Activated by Cocaine or Sucrose: Potential Role of Chromatin Remodeling

  2021cites this paper
• Cocaine-induced changes in behaviour and DNA methylation in rats are influenced by inter-individual differences in spontaneous exploratory activity

  2020cites this paper
• Protein phosphatase 1 in tumorigenesis: Is it worth a closer look?

  2020cites this paper
• The role of DNA methyltransferase activity in cocaine treatment and withdrawal in the nucleus accumbens of mice

  2020cites this paper
• Centenarians: An Example of Positive Biology

  2019cites this paper
• DNMT3a in the hippocampal CA1 is crucial in the acquisition of morphine self‐administration in rats

  2019cites this paper
• Neuroepigenetics and addictive behaviors: Where do we stand?

  2019cites this paper
• Regulation of Brain DNA Methylation Factors and of the Orexinergic System by Cocaine and Food Self-Administration

  2019influential citation
• Activity-Dependent Epigenetic Remodeling in Cocaine Use Disorder.

  2019cites this paper
• Epigenetics and Ageing

  2019cites this paper
• MeCP2 triggers diabetic cardiomyopathy and cardiac fibroblast proliferation by inhibiting RASSF1A.

  2019cites this paper
• DNA methylation signatures: Biomarkers of drug and alcohol abuse.

  2018cites this paper
• Prolonged‐access to cocaine induces distinct Homer2 DNA methylation, hydroxymethylation, and transcriptional profiles in the dorsomedial prefrontal cortex of Male Sprague‐Dawley rats

  2018cites this paper
• Cocaine‐induced epigenetic DNA modification in mouse addiction‐specific and non‐specific tissues

  2018cites this paper
• Inhibition of DNA methyltransferases regulates cocaine self‐administration by rats: a genome‐wide DNA methylation study

  2017cites this paper
• Cocaine and Epigenetics: An Overview

  2017cites this paper
• DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects

  2017influential citation
• Interactive pathways to substance abuse.

  2017cites this paper
• Dynamic Expression Changes in the Transcriptome of the Prefrontal Cortex after Repeated Exposure to Cocaine in Mice

  2017influential citation
• Drugs of Abuse and DNA Methylation in the Brain

  2016cites this paper
• DNA cytosine hydroxymethylation levels are distinct among non-overlapping classes of peripheral blood leukocytes

  2016cites this paper
• Epigenetics and addiction

  2016cites this paper
• Toxic effects of prenatal exposure to alcohol, tobacco and other drugs.

  2016cites this paper
• Persistent variations in neuronal DNA methylation following cocaine self-administration and protracted abstinence in mice.

  2015cites this paper
• Addiction et régulations épigénétiques - Implications de MeCP2 et de l’acétylation des histones

  2015cites this paper
• Cocaine triggers epigenetic alterations in the corticostriatal circuit.

  2015cites this paper
• DNA Methylation, Substance Use and Addiction: a Systematic Review of Recent Animal and Human Research from a Developmental Perspective

  2015cites this paper
• Hypermethylation of Hippocampal Synaptic Plasticity-Related genes is Involved in Neonatal Sevoflurane Exposure-Induced Cognitive Impairments in Rats

  2015cites this paper
• Reconsolidation of a cocaine associated memory requires DNA methyltransferase activity in the basolateral amygdala

  2015cites this paper
• [Epigenetics and drug addiction: a focus on MeCP2 and on histone acetylation].

  2015cites this paper
• Methyl Supplementation Attenuates Cocaine-Seeking Behaviors and Cocaine-Induced c-Fos Activation in a DNA Methylation-Dependent Manner

  2015cites this paper
• Epigenetic landscape of amphetamine and methamphetamine addiction in rodents

  2015cites this paper
• Epigenetically modified nucleotides in chronic heroin and cocaine treated mice.

  2014cites this paper
• Epigenetics of Stress, Addiction, and Resilience: Therapeutic Implications

  2014cites this paper
• Okadaic acid blocks the effects of 5-aza-2-deoxycytidine on consolidation, acquisition and retrieval of morphine-induced place preference in rats.

  2014cites this paper
• MeCP2: the long trip from a chromatin protein to neurological disorders.

  2014cites this paper
• Role of DNA methylation and the DNA methyltransferases in learning and memory

  2014cites this paper
• Differential regulation of MeCP2 and PP1 in passive or voluntary administration of cocaine or food.

  2014cites this paper
• Epigenetics of memory and plasticity.

  2014cites this paper