Discovery of a novel glucagon receptor antagonist N-[(4-{(1S)-1-[3-(3, 5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl]ethyl}phenyl)carbonyl]-β-alanine (MK-0893) for the treatment of type II diabetes.

Y. Xiong,Jian Guo,M. Candelore,Rui Liang,Corey Miller,Q. Dallas-yang,G. Jiang,Peggy E McCann,S. Qureshi,X. Tong,S. Xu,J. Shang,S. Vincent,L. Tota,Michael J Wright,Xiaodong Yang,Bei B. Zhang,J. Tata,E. Parmee

Published 2012 in Journal of Medicinal Chemistry

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