Lung heparan sulfates modulate K(fc) during increased vascular pressure: evidence for glycocalyx-mediated mechanotransduction.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  American Journal of Physiology - Lung cellular and Molecular Physiology

• Publication date

  2012-05-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1152/ajplung.00080.2011PMID 22160307PMCID PMC3362156
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Janus-faced regulation of endothelial permeability by cyclic GMP.

  2011cited by this paper
• Knockdown of lung phosphodiesterase 2A attenuates alveolar inflammation and protein leak in a two-hit mouse model of acute lung injury.

  2011cited by this paper
• Study of the therapeutic benefit of cationic copolymer administration to vascular endothelium under mechanical stress.

  2011cited by this paper
• The endothelial glycocalyx mediates shear-induced changes in hydraulic conductivity.

  2009cited by this paper
• The use of an endothelium-targeted cationic copolymer to enhance the barrier function of lung capillary endothelial monolayers.

  2009cited by this paper
• High vascular pressure-induced lung injury requires P450 epoxygenase-dependent activation of TRPV4.

  2008cited by this paper
• The Endothelial Glycocalyx: A Mechano-Sensor and -Transducer

  2008cited by this paper
• Negative-Feedback Loop Attenuates Hydrostatic Lung Edema via a cGMP-Dependent Regulation of Transient Receptor Potential Vanilloid 4

  2008cited by this paper
• Heparan sulfates mediate pressure-induced increase in lung endothelial hydraulic conductivity via nitric oxide/reactive oxygen species.

  2007cited by this paper
• The role of endothelial glycocalyx components in mechanotransduction of fluid shear stress.

  2007cited by this paper
• Transendothelial flow inhibits neutrophil transmigration through a nitric oxide-dependent mechanism: potential role for cleft shear stress.

  2007cited by this paper
• Interpreting the lung microvascular filtration coefficient.

  2007cited by this paper
• The endothelial glycocalyx: composition, functions, and visualization

  2007cited by this paper
• Fluorescence correlation spectroscopy can probe albumin dynamics inside lung endothelial glycocalyx.

  2007cited by this paper
• Comparison of two fluid-management strategies in acute lung injury.

  2006cited by this paper
• Nitric oxide activates TRP channels by cysteine S-nitrosylation

  2006cited by this paper
• Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells.

  2006cited by this paper
• Isoflurane, but Not Sevoflurane, Increases Transendothelial Albumin Permeability in the Isolated Rat Lung: Role for Enhanced Phosphorylation of Caveolin-1

  2006cited by this paper
• Peroxynitrite mediates TNF-alpha-induced endothelial barrier dysfunction and nitration of actin.

  2006cited by this paper
• Differential degradation of matrix proteoglycans and edema development in rabbit lung.

  2006cited by this paper
• Peroxynitrite mediates TNF-α-induced endothelial barrier dysfunction and nitration of actin

  2006cited by this paper
• Ca2+ Channels and Pulmonary Endothelial Permeability: Insights from Study of Intact Lung and Chronic Pulmonary Hypertension

  2006cited by this paper
• Hyperoxia increases hepatic arginase expression and ornithine production in mice.

  2006cited by this paper
• Reduced hyperpolarization in endothelial cells of rabbit aortic valve following chronic nitroglycerine administration

  2005cited by this paper
• NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-alpha.

  2004cited by this paper
• NAD(P)H oxidase mediates the endothelial barrier dysfunction induced by TNF-α

  2004cited by this paper
• Mitochondrial requirement for endothelial responses to cyclic strain: implications for mechanotransduction.

  2004cited by this paper
• Role of EETs in regulation of endothelial permeability in rat lung.

  2004cited by this paper
• Stretch activates nitric oxide production in pulmonary vascular endothelial cells in situ.

  2003cited by this paper
• Heparan Sulfate Proteoglycan Is a Mechanosensor on Endothelial Cells

  2003cited by this paper
• Anesthetic Preconditioning Improves Adenosine Triphosphate Synthesis and Reduces Reactive Oxygen Species Formation in Mitochondria after Ischemia by a Redox Dependent Mechanism

  2003cited by this paper
• Vascular segmental permeabilities at high peak inflation pressure in isolated rat lungs.

  2002cited by this paper
• Straining to understand mechanotransduction in the lung.

  2002cited by this paper
• Histidine 295 and histidine 510 are crucial for the enzymatic degradation of heparan sulfate by heparinase III.

  2000cited by this paper
• Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.

  2000cited by this paper
• Effect of ventilation on vascular permeability and cyclic nucleotide concentrations in ischemic sheep lungs.

  1999cited by this paper
• Effect of pressure on hydraulic conductivity of endothelial monolayers: role of endothelial cleft shear stress.

  1999cited by this paper
• Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome.

  1998cited by this paper
• Blood flow vs. venous pressure effects on filtration coefficient in oleic acid-injured lung.

  1998cited by this paper
• Isoproterenol attenuates high vascular pressure-induced permeability increases in isolated rat lungs.

  1997cited by this paper
• Capillary recruitment and transit time in the rat lung.

  1997cited by this paper
• Pulmonary capillary diameters and recruitment characteristics in subpleural and interior networks.

  1996cited by this paper
• Plasma proteins modify the endothelial cell glycocalyx of frog mesenteric microvessels.

  1992cited by this paper
• The effect of varying albumin concentration and hydrostatic pressure on hydraulic conductivity and albumin permeability of cultured endothelial monolayers.

  1991cited by this paper
• Permeability of frog mesenteric capillaries after partial pronase digestion of the endothelial glycocalyx.

  1990cited by this paper
• Longitudinal distribution of vascular compliance in the canine lung.

  1986cited by this paper
• Effect of lung inflation on lung blood volume and pulmonary venous flow.

  1985cited by this paper
• Optical properties of dense thin-film Si and Ge prepared by ion-beam sputtering

  1985cited by this paper
• Pulmonary interstitial compartments and tissue resistance to fluid flux.

  1984cited by this paper
• Interaction of serum proteins with lung endothelial glycocalyx: its effect on endothelial permeability.

  1984cited by this paper
• Cyclic nucleotide concentrations in tissue and perfusate of isolated rat lung.

  1984cited by this paper
• Lung tissue guanosine 3',5'-monophosphate: effects of ventilation and anesthesia.

  1978cited by this paper

• Alveolar glycocalyces during health and critical illness.

  2025cites this paper
• Transfusion-Related Acute Lung Injury (TRALI) and Transfusion-Associated Circulatory Overload (TACO): Pathophysiology, Prevention and Management

  2025cites this paper
• Updates on the Endothelial Glycocalyx in Heart Failure with Preserved Ejection Fraction.

  2025cites this paper
• Glypican 1 mechanosensing mediates eNOS uncoupling during hydrostatic pulmonary edema

  2025cites this paper
• Early Resuscitation of Patients With Non-exsanguinating Trauma Using Packed Red Blood Cells Versus Low-Volume Crystalloids: Have We Gone Too Far?

  2025cites this paper
• Systemic and Pulmonary Microcirculation, Double Microcirculation: From Basic Concepts to Treatment Key Points.

  2025cites this paper
• High Respiratory and Cardiac Drive Exacerbate Secondary Lung Injury in Patients With Critical Illness

  2024cites this paper
• Developments in Transfusion Medicine: Pulmonary Transfusion Reactions and Novel Blood Cell Labeling Techniques.

  2024cites this paper
• Endothelial Glycocalyx in Retina, Hyperglycemia, and Diabetic Retinopathy.

  2023cites this paper
• The Pulmonary Endothelial Glycocalyx Modifications in Glypican 1 Knockout Mice Do Not Affect Lung Endothelial Function in Physiological Conditions

  2023cites this paper
• Role of heparanase in pulmonary hypertension

  2023cites this paper
• The glycocalyx and calcium dynamics in endothelial cells.

  2023cites this paper
• The impact of nebivolol, carvedilol and propranolol on pulmonary microhemodynamics in case of experimental pulmonary thromboembolism in rabbits

  2022cites this paper
• Endothelial glycocalyx in hepatopulmonary syndrome: An indispensable player mediating vascular changes

  2022cites this paper
• Impact of fluid balance and blood transfusion during extracorporeal circulation on outcome for acute type A aortic dissection surgery.

  2022cites this paper
• Fluid Management During Lung Resection

  2022cites this paper
• Endothelial Heparan Sulfate Proteoglycans in Sepsis: The Role of the Glycocalyx

  2021cites this paper
• Key components of enhanced recovery after surgery protocol in lung cancer surgery

  2021cites this paper
• The recipe for TACO: A narrative review on the pathophysiology and potential mitigation strategies of transfusion-associated circulatory overload.

  2021cites this paper
• Endothelial Glycocalyx as a Regulator of Fibrotic Processes

  2021cites this paper
• Restrictive intraoperative fluid management was associated with higher incidence of composite complications compared to less restrictive strategies in open thoracotomy: A retrospective cohort study

  2020cites this paper
• Syndecan-1 and Glypican-1 Knockout Alters Body Water Balance and Urine Response to Fluid Challenge in Mice

  2020cites this paper
• The Glycocalyx and Pressure-Dependent Transcellular Albumin Transport

  2020cites this paper
• The Glycocalyx and Its Role in Vascular Physiology and Vascular Related Diseases

  2020cites this paper
• The pathological relevance of increased endothelial glycocalyx permeability.

  2020cites this paper
• Heparan sulfate proteoglycan, integrin, and syndecan‐4 are mechanosensors mediating cyclic strain‐modulated endothelial gene expression in mouse embryonic stem cell‐derived endothelial cells

  2019cites this paper
• Ropivacaine inhibits pressure‐induced lung endothelial hyperpermeability in models of acute hypertension

  2019cites this paper
• Endothelial glycocalyx as a potential theriapeutic target in organ injuries

  2019cites this paper
• Transfusion-Associated Circulatory Overload: A Clinical Perspective.

  2019cites this paper
• 4-1-2018 Perioperative Implication of the Endothelial Glycocalyx

  2019cites this paper
• Modeling of Transport Mechanisms in the Respiratory System: Validation via Congestive Heart Failure Patients

  2019influential citation
• Physiology of the Lateral Decubitus Position, Open Chest, and One-Lung Ventilation

  2019cites this paper
• Fluid Management in Thoracic Surgery

  2019cites this paper
• Cardiovascular Physiology

  2019cites this paper
• Molecular and Functional Insights Into the Pulmonary Vasculature

  2018cites this paper
• Perioperative implication of the endothelial glycocalyx

  2018cites this paper
• Characterization of Tie2 signalling during acute inflammation

  2018cites this paper
• The Pulmonary Endothelial Glycocalyx in ARDS: A Critical Role for Heparan Sulfate.

  2018cites this paper
• The Pulmonary Vascular Barrier: Insights into Structure, Function, and Regulatory Mechanisms.

  2018cites this paper
• Pressure-dependent NOS activation contributes to endothelial hyperpermeability in a model of acute heart failure

  2018influential citation
• Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate

  2018cites this paper
• Efecto modulador del sevoflurano sobre la respuesta inflamatoria sistémica secundaria a la ventilación unipulmonar en un modelo experimental de cirugía de resección pulmonar

  2017cites this paper
• Wound Healing and the Non‐cellular Microenvironment

  2017cites this paper
• Section 5: Pulmonary, Renal, Endocrine Pharmacology

  2017cites this paper
• The Balance Between Metalloproteinases and TIMPs: Critical Regulator of Microvascular Endothelial Cell Function in Health and Disease.

  2017cites this paper
• More than a biomarker: the systemic consequences of heparan sulfate fragments released during endothelial surface layer degradation (2017 Grover Conference Series)

  2017cites this paper
• Hypercapnic acidosis attenuates pressure-dependent increase in whole-lung filtration coefficient (Kf)

  2017cites this paper
• Assessment of Pulmonary Edema: Principles and Practice.

  2017cites this paper
• The Biomechanical Effects of Resuscitation Colloids on the Compromised Lung Endothelial Glycocalyx

  2016cites this paper
• Heparan Sulfate in the Developing, Healthy, and Injured Lung.

  2016cites this paper
• The newest progress of research on acute trauma-induced coagulopathy

  2016cites this paper
• Preliminary in vitro analysis of mechanism of cardiac microvascular endothelial barrier function.

  2016influential citation
• Septic Murine Pulmonary Microvascular Endothelial Cell Barrier Dysfunction is Regulated by Tissue Inhibitor of Metalloproteinases 3

  2015cites this paper
• Nutritional and other types of oedema, albumin, complex carbohydrates and the interstitium – a response to Malcolm Coulthard's hypothesis: Oedema in kwashiorkor is caused by hypo-albuminaemia

  2015cites this paper
• Extravascular Lung Water and Tissue Perfusion Biomarkers After Lung Resection Surgery Under a Normovolemic Fluid Protocol.

  2015cites this paper
• THE GLYCOCALYX AND TRAUMA: A REVIEW

  2015cites this paper
• Nutritional and other types of oedema, albumin, complex carbohydrates and the interstitium - a response to Malcolm Coulthard's hypothesis: Oedema in kwashiorkor is caused by hypo-albuminaemia.

  2015cites this paper
• Lung Injury After One-Lung Ventilation: A Review of the Pathophysiologic Mechanisms Affecting the Ventilated and the Collapsed Lung

  2015cites this paper
• Coming to terms with tissue engineering and regenerative medicine in the lung.

  2015cites this paper
• Bioengineering the Lung : Molecules , Materials , Matrix , Morphology , and Mechanics Coming to terms with tissue engineering and regenerative medicine in the lung

  2015cites this paper
• The Regulation and Perturbation of Vascular Endothelial Permeability

  2014cites this paper
• Novel regulators of endothelial barrier function.

  2014cites this paper
• Shear-induced endothelial NOS activation and remodeling via heparan sulfate, glypican-1, and syndecan-1.

  2014cites this paper
• OPINION Fluid management in thoracic surgery

  2013cites this paper
• The endothelial glycocalyx

  2013cites this paper
• Special article: the endothelial glycocalyx: emerging concepts in pulmonary edema and acute lung injury.

  2013cites this paper
• Fluid management in thoracic surgery

  2013cites this paper
• Heparanase mediates renal dysfunction during early sepsis in mice

  2013cites this paper
• Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction.

  2013cites this paper
• Fluid Management in Thoracic Surgery

  2013cites this paper
• Caveolin-1 regulation of endothelial nitric oxide synthase function and oxidative stress in the endothelium

  2012cites this paper
• Epinephrine Induces Rapid Deterioration in Pulmonary Oxygen Exchange in Intact, Anesthetized Rats: A Flow and Pulmonary Capillary Pressure-dependent Phenomenon

  2012cites this paper
• Physiology of the Lateral Decubitus Position, Open Chest and One-Lung Ventilation

  2011cites this paper
• V. I. Evlakhov, I. Z. Poyassov. ALFA-ADRENERGIC MECHANISMS OF THE PULMO- NARY VEINS CONSTRICTOR REACTIONS IN THE EXPERIMENTAL PULMONARY THROMBOEMBOLISM

  year unknowncites this paper