Time course and cellular localization of interleukin-10 mRNA and protein expression in autoimmune inflammation of the rat central nervous system.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  American Journal of Pathology

• Publication date

  1998-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 9546358PMCID PMC1858238
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• IL-10 suppresses experimental autoimmune neuritis and down-regulates TH1-type immune responses.

  1997cited by this paper
• Late Complications of Immune Deviation Therapy in a Nonhuman Primate

  1996cited by this paper
• Functional diversity of helper T lymphocytes

  1996cited by this paper
• The paradoxical effects of interleukin 10 in the immunoregulation of autoimmune diabetes.

  1996cited by this paper
• Microglia induce CD4 T lymphocyte final effector function and death

  1996cited by this paper
• IL‐10 fails to abrogate experimental autoimmune encephalomyelitis

  1996cited by this paper
• Differential expression of interleukin‐10 mRNA in Wallerian degeneration and immune‐mediated inflammation of the rat peripheral nervous system

  1996cited by this paper
• Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor alpha and tumor necrosis factor beta.

  1995cited by this paper
• The adhesion molecule and cytokine profile of multiple sclerosis lesions

  1995cited by this paper
• Production of interleukin-10 by mouse glial cells in culture.

  1994cited by this paper
• Multiple sclerosis. Immunomodulatory effects of human astrocytes on T cells.

  1994cited by this paper
• Interleukin‐10 prevents experimental allergic encephalomyelitis in rats

  1994cited by this paper
• IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression.

  1993cited by this paper
• Localization of interferon-gamma and Ia-antigen in T cell line-mediated experimental autoimmune encephalomyelitis.

  1993cited by this paper
• In situ inactivation of infiltrating T cells in the central nervous system with autoimmune encephalomyelitis. The role of astrocytes.

  1993cited by this paper
• Experimental autoimmune encephalomyelitis as a model of immune-mediated CNS disease.

  1993cited by this paper
• Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery.

  1992cited by this paper
• Synthesis and characterization of rat interleukin-10 (IL-10) cDNA clones from the RNA of cultured OX8- OX22- thoracic duct T cells.

  1992cited by this paper
• Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

  1991cited by this paper
• Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

  1991cited by this paper
• Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

  1989cited by this paper
• Experimental allergic encephalomyelitis.

  1988cited by this paper
• Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice

  1984cited by this paper
• Biology of disease. Analysis of autoimmune demyelination: its impact upon multiple sclerosis.

  1984cited by this paper
• Experimental allergic encephalomyelitis.

  1949cited by this paper

• An Activation-Specific Anti-Mac-1 Designed-Ankyrin-Repeat-Protein Attenuates Colitis in Mice

  2023cites this paper
• Cellular Sources and Neuroprotective Roles of Interleukin-10 in the Facial Motor Nucleus after Axotomy

  2022cites this paper
• Chronic intestinal inflammation suppresses brain activity by inducing neuroinflammation in mice.

  2021cites this paper
• Stimulus‐dependent modifications in astrocyte‐derived extracellular vesicle cargo regulate neuronal excitability

  2020cites this paper
• Nanomodulation of Macrophages in Multiple Sclerosis

  2019cites this paper
• Altered neurotrophic factors' expression profiles in the nucleus of the solitary tract of spontaneously hypertensive rats

  2016cites this paper
• Balancing the immune response in the brain: IL-10 and its regulation

  2016cites this paper
• Classical and Alternative Activation of Cyanobacterium Oscillatoria sp. Lipopolysaccharide-Treated Rat Microglia in vitro.

  2016influential citation
• Improved Inflammatory Balance of Human Skeletal Muscle during Exercise after Supplementations of the Ginseng-Based Steroid Rg1

  2015cites this paper
• High interleukin-10 expression within the central nervous system may be important for initiation of recovery of Dark Agouti rats from experimental autoimmune encephalomyelitis.

  2013cites this paper
• PACAP Attenuates NMDA-Induced Retinal Damage in Association with Modulation of the Microglia/Macrophage Status into an Acquired Deactivation Subtype

  2013cites this paper
• The potential role of proinflammatory and antiinflammatory cytokines in Alzheimer disease pathogenesis

  2012cites this paper
• Pathogenic and regulatory roles for B cells in experimental autoimmune encephalomyelitis

  2012cites this paper
• Inflammation in ischemic stroke subtypes.

  2012cites this paper
• Interleukin‐10 overexpression does not synergize with the neuroprotective action of RGD‐containing vectors after postnatal brain excitotoxicity but modulates the main inflammatory cell responses

  2012influential citation
• Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts

  2011cites this paper
• Evaluation d'un protocole préclinique d'immunothérapie dirigé contre les tumeurs cérébrales et du potentiel de présentation antigénique croisée des cellules microgliales adultes

  2011cites this paper
• Role of Cytokines as Mediators and Regulators of Microglial Activity in Inflammatory Demyelination of the CNS

  2010cites this paper
• Macrophages/Microglie et formes progressives dans la sclérose en plaques Analyse histologique et moléculaire

  2010cites this paper
• Interleukin-10 and Interleukin-10 Receptor-I Are Upregulated in Glial Cells After an Excitotoxic Injury to the Postnatal Rat Brain

  2009cites this paper
• Interleukin‐10 provides direct trophic support to neurons

  2009cites this paper
• Tolerance induction in experimental autoimmune encephalomyelitis using non-myeloablative hematopoietic gene therapy with autoantigen.

  2009cites this paper
• Inoculation of Bacillus Calmette-Guerin to mice induces an acute episode of sickness behavior followed by chronic depressive-like behavior.

  2008cites this paper
• All-or-nothing type biphasic cytokine production of human lymphocytes after exposure to Alzheimer's beta-amyloid peptide.

  2008cites this paper
• Caractérisation des cellules microgliales adultes et de leur potentiel en immunothérapie des tumeurs cérébrales

  2007cites this paper
• Regulation of IL-10 expression by upstream stimulating factor (USF-1) in glioma-associated microglia.

  2007cites this paper
• Resistance to experimental autoimmune encephalomyelitis development in Lewis rats from a conventional animal facility.

  2007cites this paper
• T-cell cytokines in injury-induced neural damage and repair

  2007cites this paper
• TREM2-Transduced Myeloid Precursors Mediate Nervous Tissue Debris Clearance and Facilitate Recovery in an Animal Model of Multiple Sclerosis

  2007cites this paper
• TREM 2-Transduced Myeloid Precursors Mediate Nervous Tissue Debris Clearance and Facilitate Recovery in an Animal Model of Multiple Sclerosis

  2007cites this paper
• B Cell Regulation of CD4+CD25+ T Regulatory Cells and IL-10 Via B7 is Essential for Recovery From Experimental Autoimmune Encephalomyelitis1

  2007influential citation
• This information is current as Autoimmune Encephalomyelitis Essential for Recovery From Experimental Regulatory Cells and IL-10 Via B 7 is T + CD 25 + B Cell Regulation of CD 4

  2007influential citation
• Elevated levels of inflammatory biomarkers in the cerebrospinal fluid after coronary artery bypass surgery are predictors of cognitive decline.

  2006cites this paper
• Cytokine profile of iron-laden macrophages: implications for cellular magnetic resonance imaging.

  2006cites this paper
• Pathophysiology of interleukin-23 in experimental autoimmune encephalomyelitis.

  2006cites this paper
• Natural recovery and protection from autoimmune encephalomyelitis

  2005cites this paper
• Natural Recovery and Protection from Autoimmune Encephalomyelitis: Contribution of CD4+CD25+ Regulatory Cells within the Central Nervous System1

  2005cites this paper
• New insights into cell responses involved in experimental autoimmune encephalomyelitis and multiple sclerosis.

  2005cites this paper
• Neutralization of chemokines RANTES and MIG increases virus antigen expression and spinal cord pathology during Theiler's virus infection

  2005cites this paper
• Role of Microglia and Macrophages in Eae

  2005cites this paper
• Characterisation of inflammation in the central nervous system induced by lipoteichoic acid from Staphylococcus aureus : role of glia in the mechanisms of neuronal cell death

  2005cites this paper
• Cytokines and Brain

  2005cites this paper
• Brain microglia and blood-derived macrophages: molecular profiles and functional roles in multiple sclerosis and animal models of autoimmune demyelinating disease.

  2004cites this paper
• Investigating the regulatory cells that mediate recovery from CNS-targeted autoimmune disease

  2004cites this paper
• Biphasic form of experimental autoimmune neuritis in dark agouti rats and its oral therapy by antigen‐specific tolerization

  2004cites this paper
• CD8+ phagocyte recruitment in rat experimental autoimmune encephalomyelitis: association with inflammatory tissue destruction.

  2003cites this paper
• Induction of inducible nitric oxide synthase mRNA expression and nitric oxide production from macrophages stimulated with high-molecular size mite antigen HM1

  2003cites this paper
• Regional and temporal expression patterns of interleukin-10, interleukin-10 receptor and adhesion molecules in the rat spinal cord during chronic relapsing EAE.

  2003cites this paper
• Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system.

  2002cites this paper
• Blockade of signaling via the very late antigen (VLA-4) and its counterligand vascular cell adhesion molecule-1 (VCAM-1) causes increased T cell apoptosis in experimental autoimmune neuritis

  2002cites this paper
• Interleukin-18 Expression after Focal Ischemia of the Rat Brain: Association with the Late-Stage Inflammatory Response

  2002influential citation
• Interleukin‐13 and ‐4 induce death of activated microglia

  2002cites this paper
• Theiler's virus infection induces the expression of cyclooxygenase-2 in murine astrocytes: inhibition by the anti-inflammatory cytokines interleukin-4 and interleukin-10.

  2002cites this paper
• Molecular and Cellular Biology of Neuroprotection in the CNS

  2002cites this paper
• Anti-Inflammatory Cytokines: Expression and Action in the Brain

  2002cites this paper
• Induction of the proinflammatory cytokine interleukin‐18 by axonal injury

  2001cites this paper
• Lipopolysaccharide‐induced switch between retinoid receptor (RXR) α and glucocorticoid attenuated response gene (GARG)‐16 messenger RNAs in cultured rat microglia

  2001cites this paper
• Beta-amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology.

  2001cites this paper
• STAT expression and localization in the central nervous system during autoimmune encephalomyelitis in Lewis rats.

  2001cites this paper
• Immune function of microglia

  2001influential citation
• Functional Maturation of Adult Mouse Resting Microglia into an APC Is Promoted by Granulocyte-Macrophage Colony-Stimulating Factor and Interaction with Th1 Cells1

  2000cites this paper
• HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones

  2000cites this paper
• Cytokines in CNS disorders: neurotoxicity versus neuroprotection.

  2000cites this paper
• Molecular Mechanisms of High-Dose Antigen Therapy in Experimental Autoimmune Encephalomyelitis: Rapid Induction of Th1-Type Cytokines and Inducible Nitric Oxide Synthase1

  2000influential citation
• IL-10 Kinetics in Thyroiditis-Prone BB/Wor Rats

  2000cites this paper
• Potentiation of Endogenous Fibrinolysis and Rescue from Lung Ischemia/Reperfusion Injury in Interleukin (IL)-10-reconstituted IL-10 Null Mice*

  2000cites this paper
• IFN-γ and LPS-Mediated IL-10–Dependent Suppression of Retinal Microglial Activation

  2000cites this paper
• Interleukin-4-inhibited mRNA expression in mixed rat glial and in isolated microglial cultures.

  2000cites this paper
• Interleukin‐10, interleukin‐4, and transforming growth factor‐β differentially regulate lipopolysaccharide‐induced production of pro‐inflammatory cytokines and nitric oxide in co‐cultures of rat astroglial and microglial cells

  2000cites this paper
• Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis.

  2000cites this paper
• IFN-gamma and LPS-mediated IL-10-dependent suppression of retinal microglial activation.

  2000cites this paper
• Oxide Synthase Th 1-Type Cytokines and Inducible Nitric Encephalomyelitis : Rapid Induction of Therapy in Experimental Autoimmune Molecular Mechanisms of High-Dose Antigen

  2000cites this paper
• Microglial/macrophage expression of interleukin 10 in human glioblastomas

  1999cites this paper
• The role of microglia and macrophages in the pathophysiology of the CNS.

  1999cites this paper
• Central injection of IL-10 antagonizes the behavioural effects of lipopolysaccharide in rats.

  1999cites this paper
• Opposite effects of interferon‐γ and prostaglandin E2 on tumor necrosis factor and interleukin‐10 production in microglia: A regulatory loop controlling microglia pro‐ and anti‐inflammatory activities

  1999cites this paper
• IL-10 as a mediator in the HPA axis and brain.

  1999cites this paper
• Differential induction of interleukin-12, interleukin-18, and interleukin-1beta converting enzyme mRNA in experimental autoimmune encephalomyelitis of the Lewis rat.

  1998cites this paper
• Inflammation and glial responses in ischemic brain lesions.

  1998cites this paper