The magnitude of the hypercholesterolemia of hypothyroidism is associated with variation in the low density lipoprotein receptor gene.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Journal of Clinical Endocrinology and Metabolism

• Publication date

  1993-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1210/JCEM.77.1.8100826PMID 8100826
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Influence of apolipoproteins on the anatomical distribution of arterial disease.

  1991cited by this paper
• Identification of the 664 proline to leucine mutation in the low density lipoprotein receptor in four unrelated patients with familial hypercholesterolaemia in the UK

  1991cited by this paper
• Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors.

  1991cited by this paper
• A major thyroid hormone response element in the third intron of the rat growth hormone gene.

  1990cited by this paper
• A study of familial hypercholesterolaemia in Iceland using RFLPs.

  1989cited by this paper
• Can thyroxine halt the progression of peripheral arterial disease?

  1989cited by this paper
• Influence of smoking and plasma factors on patency of femoropopliteal vein grafts.

  1989cited by this paper
• Polymorphic DNA haplotypes at the LDL receptor locus.

  1989cited by this paper
• Regulation of gene expression by thyroid hormone.

  1988cited by this paper
• The steroid and thyroid hormone receptor superfamily.

  1988cited by this paper
• Lipoproteins, lipolytic enzymes, and hormonal status in hypothyroid women at different levels of substitution.

  1988cited by this paper
• Intra- and interindividual biological variation of five analytes used in assessing thyroid function: implications for necessary standards of performance and the interpretation of results.

  1986cited by this paper
• The LDL receptor gene: a mosaic of exons shared with different proteins.

  1985cited by this paper
• Serum lipids and apolipoproteins A‐I, A‐II and B in primary hypothyroidism before and during treatment

  1984cited by this paper
• Serum lipoprotein and apolipoprotein concentrations and tissue lipoprotein‐lipase activity in overt and subclinical hypothyroidism: the effect of substitution therapy

  1981cited by this paper
• Defects of receptor-mediated low density lipoprotein catabolism in homozygous familial hypercholesterolemia and hypothyroidism in vivo.

  1981cited by this paper
• Thyroid hormone action at the cellular level.

  1979cited by this paper
• Symptomless autoimmune thyroiditis in coronary heart-disease.

  1972cited by this paper
• Preclinical hypothyroidism: a risk factor for coronary heart-disease.

  1971cited by this paper
• Coronary-artery disease in hypothyroidism. Observations in clinical myxoedema.

  1967cited by this paper
• Coronary-artery disease in hypothyroidism.

  1967cited by this paper
• The significance of alterations in serum lipids in thyroid dysfunction. I. The relation between serum lipoproteins, carotenoids and vitamin A in hypothyroidism and thyrotoxicosis.

  1965cited by this paper
• Statistical Tables for Biological, Agricultural and Medical Research

  1956cited by this paper

• Body composition changes across a spectrum of hypothyroidism severity - a systematic review and meta-analysis

  2025cites this paper
• Hoffmann’s Syndrome as a Rare Manifestation of Hypothyroidism: Current Views on Mechanisms of Development and Diagnosis

  2024cites this paper
• Actions of thyroid hormones and thyromimetics on the liver

  2024influential citation
• Development of Thyroid Hormones and Synthetic Thyromimetics in Non-Alcoholic Fatty Liver Disease

  2022cites this paper
• Clinical Aspects of Genetic and Non-Genetic Cardiovascular Risk Factors in Familial Hypercholesterolemia

  2022cites this paper
• Effects of Thyroid Hormones on Lipid Metabolism Pathologies in Non-Alcoholic Fatty Liver Disease

  2022cites this paper
• Assessment of Oxidative Stress Index in Sub-clinical Hypothyroidism

  2021cites this paper
• RELATIONSHIP BETWEEN OVERT HYPOTHYROIDISM AND DYSLIPIDEMIA: A CROSS- SECTIONAL STUDY IN TRIBAL POPULATION OF BANKURA, WEST BENGAL

  2018cites this paper
• Effect of Clinical and Subclinical Hypothyroidism on some lipid values among Sudanese females

  2015cites this paper
• Характеристика липидных параметров у женщин в менопаузе с компенсированным гипотиреозом в исходе аутоиммунного тиреоидита

  2014cites this paper
• Polymorphism AvaII of the LDL receptor (rs5925) is associated with carotid-intima media thickness in patients with diabetes mellitus type 2

  2014cites this paper
• Morphological and functional events associated to weaning in rabbits.

  2014cites this paper
• The Relationship between serum levels of Thyroid Hormones (T3, T4) Thyroid-Stimulating Hormone (TSH) and Serum Lipid Profile

  2013cites this paper
• Guidelines for the Management of Dyslipidemia and Thyroid Dysfunction

  2013cites this paper
• The Roles of Genetic Polymorphisms and Human Immunodeficiency Virus Infection in Lipid Metabolism

  2013cites this paper
• Evaluation of acute physiological and molecular alterations in surgically developed hypothyroid Wistar rats

  2013cites this paper
• RELAÇÃO ENTRE OS NÍVEIS DE COLESTEROL TOTAL E HIPOTIREOIDISMO, EM INDIVÍDUOS DA CIDADE DE BENTO GONÇALVES/RS

  2013cites this paper
• Association of Lipids with Oxidative Stress Biomarkers in Subclinical Hypothyroidism

  2012cites this paper
• Evaluation of Cardioprotective Effect of 3,5,3′-Tri-iodo-L-thyronine in Isoproterenol-Induced Cardiotoxicity

  2011cites this paper
• Effects of Thyroid Dysfunction on Lipid Profile

  2011influential citation
• Alterações bioquímicas e estresse oxidativo associados ao hipotireoidismo

  2010cites this paper
• Prevalence of hypercholesterolemia in hypothyroidism compared with euthyroid controls: effects of levothyroxin replacement therapy.

  2010cites this paper
• Association between thyroid hormones, lipids and oxidative stress biomarkers in overt hypothyroidism

  2010cites this paper
• Thyroid Hormones and Lipid Metabolism: Thyromimetics as Anti-Atherosclerotic Agents?

  2009cites this paper
• The beneficial effect of L-thyroxine on cardiovascular risk factors, endothelial function, and quality of life in subclinical hypothyroidism: randomized, crossover trial.

  2007cites this paper
• Unmasking of type III hyperlipoproteinemia by hypothyroidism: a dramatic illustration of altered lipoprotein metabolism in a postpartum woman.

  2005cites this paper
• Hiperlipidemias secundarias. Mecanismos etiopatogénicos. Impacto vascular y tisular de las hiperlipidemias. Historia natural

  2004cites this paper
• Decreased activity of lecithin:cholesterol acyltransferase and hepatic lipase in chronic hypothyroid rats: Implications for reverse cholesterol transport

  2003cites this paper
• Dyslipidemia in patients with thyroid disorders.

  2002cites this paper
• Case finding and screening strategies for thyroid dysfunction.

  2002cites this paper
• Chronic hypothyroidism induces abnormal structure of high-density lipoproteins and impaired kinetics of apolipoprotein A-I in the rat.

  2002cites this paper
• Thyroid hormones in the pathogenesis and treatment of obesity.

  2002cites this paper
• Thyroid Disease and Lipids

  2002influential citation
• An Association Between Varying Degrees of Hypothyroidism and Hypercholesterolemia in Women: The Thyroid-Cholesterol Connection.

  2001cites this paper
• Clinical and laboratory evaluation of hyperlipemic and hypothyroid patients.

  2001cites this paper
• III Diretrizes Brasileiras Sobre Dislipidemias e Diretriz de Prevençäo da Aterosclerose do Departamento de Aterosclerose da Sociedade Brasileira de Cardiologia

  2001cites this paper
• Physiological and molecular basis of thyroid hormone action.

  2001cites this paper
• The relationship between thyrotropin and low density lipoprotein cholesterol is modified by insulin sensitivity in healthy euthyroid subjects.

  2001cites this paper
• Physiological and Molecular Basis of Thyroid Hormone Action

  2001cites this paper
• Thyrotropin Regulation of Cyclic Adenosine Monophosphate Production in Human Coronary Artery Smooth Muscle Cells

  2000cites this paper
• Changes in plasma low-density lipoprotein (LDL)- and high-density lipoprotein cholesterol in hypo- and hyperthyroid patients are related to changes in free thyroxine, not to polymorphisms in LDL receptor or cholesterol ester transfer protein genes.

  2000influential citation
• Plasma cholesteryl ester transfer protein activity is high in infants and is not affected by thyroid hormones.

  2000cites this paper
• The thyroid-cholesterol connection: an association between varying degrees of hypothyroidism and hypercholesterolemia in women.

  2000cites this paper
• Effect of hypothyroidism on blood lipid concentrations in horses.

  1999cites this paper
• Changes in serum apolipoprotein concentrations after L-thyroxine therapy in infants with congenital hypothyroidism.

  1999cites this paper
• Low-Density Lipoprotein Size in Primary Hypothyroidism

  1999cites this paper
• Effects of Ava II and Hinc II polymorphisms at the LDL receptor gene on serum lipid levels of Brazilian individuals with high risk for coronary heart disease

  1999cites this paper
• Lipoprotein(a) and other lipoproteins in hypothyroid patients before and after thyroid replacement therapy.

  1999cites this paper
• Association and linkage of LDLR gene variation with variation in plasma low density lipoprotein cholesterol

  1998cites this paper
• [Lipidic changes in subclinical hypothyroidism. Evolution according to whether or not corrections are made of TSH levels].

  1998cites this paper
• Thyroid functions and serum lipids in older women: a population-based study.

  1998cites this paper
• Thyroid Function and Serum Lipids in Older Women: A Population-based Study

  1998cites this paper
• High Lipid Levels in Slovak Rural Population Consequence of Thyroid Dysfunction or Nutritional Status? a

  1997cites this paper
• Effect of thyroid substitution on hypercholesterolaemia in patients with subclinical hypothyroidism: a reanalysis of intervention studies

  1996cites this paper
• 177 Cardiovascular Risk Factors, Classified in 10 Categories, to be Considered in the Prevention of Cardiovascular Diseases: An Update of the Original 1982 Article Containing 96 Risk Factors

  1996cites this paper
• Prevalence and correction of hypothyroidism in a large cohort of patients referred for dyslipidemia.

  1995cites this paper
• Effects of L-thyroxine on serum lipid profiles in infants with congenital hypothyroidism.

  1995cites this paper
• The aging thyroid.

  1995cites this paper
• Thyroid autoimmunity and ageing.

  1995cites this paper
• Triiodothyronine rapidly lowers plasma lipoprotein (a) in hypothyroid subjects.

  1995cites this paper
• The molecular basis of thyroid hormone action.

  1994cites this paper