Sperm maturity and treatment choice of in vitro fertilization (IVF) or intracytoplasmic sperm injection: diminished sperm HspA2 chaperone levels predict IVF failure.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Fertility and Sterility

• Publication date

  2002-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0015-0282(02)03073-XPMID 12009343
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2000cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1992cited by this paper
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  1990cited by this paper
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  1990cited by this paper
• Correlation between sperm creatine phosphokinase activity and sperm concentrations in normospermic and oligospermic men.

  1988cited by this paper
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  1986cited by this paper
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  1963cited by this paper

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