Pitfalls and Opportunities for Epigenomic Analyses Focused on Disease Diagnosis, Prognosis, and Therapy.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  TIPS - Trends in Pharmacological Sciences

• Publication date

  2017-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.tips.2017.05.007PMID 28625497
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pharmacoepigenetics and Toxicoepigenetics: Novel Mechanistic Insights and Therapeutic Opportunities.

  2018cited by this paper
• Spectroscopic quantification of 5-hydroxymethylcytosine in genomic DNA using boric acid-functionalized nano-microsphere fluorescent probes.

  2017cited by this paper
• Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA

  2017cited by this paper
• Epigenome-wide association study of DNA methylation in panic disorder

  2017cited by this paper
• Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis.

  2016cited by this paper
• Ten-eleven translocation 1 (TET1) methylation is associated with childhood asthma and traffic-related air pollution.

  2016cited by this paper
• Profiling genome-wide DNA methylation

  2016cited by this paper
• Common errors in mass spectrometry‐based analysis of post‐translational modifications

  2016cited by this paper
• An epigenetic mechanism links socioeconomic status to changes in depression-related brain function in high-risk adolescents

  2016cited by this paper
• Single base resolution analysis of 5-hydroxymethylcytosine in 188 human genes: implications for hepatic gene expression

  2016cited by this paper
• Recent advances in ChIP-seq analysis: from quality management to whole-genome annotation

  2016cited by this paper
• Identification of tissue-specific cell death using methylation patterns of circulating DNA

  2016cited by this paper
• De novo DNA methylation drives 5hmC accumulation in mouse zygotes

  2016cited by this paper
• Epigenetic activation of the drug transporter OCT2 sensitizes renal cell carcinoma to oxaliplatin

  2016cited by this paper
• Hepatic stellate cell transdifferentiation involves genome-wide remodeling of the DNA methylation landscape.

  2016cited by this paper
• Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin.

  2016cited by this paper
• DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy

  2016cited by this paper
• Epigenome-wide Association Studies and the Interpretation of Disease -Omics

  2016cited by this paper
• Single-cell genome-wide bisulfite sequencing uncovers extensive heterogeneity in the mouse liver methylome

  2016cited by this paper
• Variation in 5-hydroxymethylcytosine across human cortex and cerebellum

  2016cited by this paper
• DNA Methylation of ADME Genes

  2016cited by this paper
• A Novel method for the simultaneous identification of methylcytosine and hydroxymethylcytosine at a single base resolution

  2016cited by this paper
• Effect of genotype and methylation of CYP2D6 on smoking behaviour

  2015cited by this paper
• Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes

  2015cited by this paper
• Genetic and epigenetic regulation of gene expression in fetal and adult human livers

  2014cited by this paper
• Genomic imprinting in mammals.

  2014cited by this paper
• Coverage recommendations for methylation analysis by whole genome bisulfite sequencing

  2014cited by this paper
• Sequencing depth and coverage: key considerations in genomic analyses

  2014cited by this paper
• Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial.

  2014cited by this paper
• Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain

  2014cited by this paper
• An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia

  2014cited by this paper
• Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function

  2013cited by this paper
• DNA Methylation of the SLC16A3 Promoter Regulates Expression of the Human Lactate Transporter MCT4 in Renal Cancer with Consequences for Clinical Outcome

  2013cited by this paper
• Recommendations for the design and analysis of epigenome-wide association studies

  2013cited by this paper
• Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

  2013cited by this paper
• Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma.

  2012cited by this paper
• Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine

  2012cited by this paper
• Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liver

  2012cited by this paper
• Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution

  2012cited by this paper
• A double-blind, placebo-controlled, randomized phase III trial of chemotherapy plus epigenetic therapy with hydralazine valproate for advanced cervical cancer. Preliminary results

  2011cited by this paper
• Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.

  2011cited by this paper
• 5-Hydroxymethylcytosine: a new kid on the epigenetic block?

  2011cited by this paper
• 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells

  2011cited by this paper
• The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

  2010cited by this paper
• A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations.

  2010cited by this paper
• Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates

  2010cited by this paper
• The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

  2009cited by this paper
• Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance.

  2009cited by this paper
• ChIP–seq: advantages and challenges of a maturing technology

  2009cited by this paper
• Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

  2009cited by this paper
• Inferring causal relationships among different histone modifications and gene expression.

  2008cited by this paper
• Cause and Consequences of Genetic and Epigenetic Alterations in Human Cancer

  2008cited by this paper
• The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model

  2007cited by this paper
• MDR1 gene overexpression and altered degree of methylation at the promoter region in bladder cancer during chemotherapeutic treatment.

  2000cited by this paper
• Rapid activation of MDR1 gene expression in human metastatic sarcoma after in vivo exposure to doxorubicin.

  1999cited by this paper
• International Journal of Molecular Sciences the Importance of Patient-specific Factors for Hepatic Drug Response and Toxicity

  year unknowncited by this paper

• Multi-Omics Profiling for Health

  2023cites this paper
• Non-alcoholic fatty liver disease - opportunities for personalized treatment and drug development

  2022cites this paper
• Analysis of pharmacogenomic very important pharmacogenomic variants: CYP3A5, ACE, PTGS2 and NAT2 genes in Chinese Bai population.

  2022cites this paper
• Family-effects in the epigenomic response of red blood cells to a challenge test in the European sea bass (Dicentrarchus labrax, L.)

  2021cites this paper
• Epigenomic response of red blood cells to a stress challenge in the European sea bass (Dicentrarchus labrax, L.)

  2021cites this paper
• Family-effects in the epigenomic response of red blood cells to a challenge test in the European sea bass (Dicentrarchus labrax, L.)

  2021cites this paper
• Pharmacogenomics Biomarkers of Soft Tissue Sarcoma Therapies

  2020cites this paper
• Genome-wide epigenomic stress response in the European sea bass (Dicentrarchus labrax, L.)

  2020cites this paper
• Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity

  2019cites this paper
• Pharmacoepigenetics and Toxicoepigenetics: Novel Mechanistic Insights and Therapeutic Opportunities.

  2018cites this paper
• Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

  2017cites this paper
• Epigenetics and epigenomics: the future of nutritional interventions?

  2017cites this paper