The genotoxic carcinogen chromium(VI) alters the metal-inducible expression but not the basal expression of the metallothionein gene in vivo.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Carcinogenesis

• Publication date

  1994-05-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1093/CARCIN/15.5.1089PMID 8200074
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Preferential alteration of inducible gene expression in vivo by carcinogens that induce bulky DNA lesions

  1993cited by this paper
• Transcriptional inhibition by carcinogenic chromate: Relationship to DNA damage

  1992cited by this paper
• Inhibition of protein synthesis increases the transcription of the phenobarbital-inducible CYP2H1 and CYP2H2 genes in chick embryo hepatocytes.

  1992cited by this paper
• Complexing of actin and other nuclear proteins to DNA by cis-diamminedichloroplatinum(II) and chromium compounds.

  1991cited by this paper
• Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription.

  1991cited by this paper
• Heterogeneity of DNA repair at the gene level.

  1991cited by this paper
• Chromium bound to DNA alters cleavage by restriction endonucleases.

  1991cited by this paper
• DNA-protein complexes induced by chromate and other carcinogens.

  1991cited by this paper
• Alteration in restriction enzyme digestion patterns detects DNA--protein complexes induced by chromate.

  1991cited by this paper
• Genotoxicity of chromium compounds. A review.

  1990cited by this paper
• Induction of hepatic metallothionein by intraperitoneal metal injection: an associated inflammatory response.

  1990cited by this paper
• Expression of 5-aminolaevulinate synthase and cytochrome P-450 mRNAs in chicken embryo hepatocytes in vivo and in culture. Effect of porphyrinogenic drugs and haem.

  1989cited by this paper
• Molecular basis of hexavalent chromium carcinogenicity: effect on gene expression.

  1989cited by this paper
• Differential Effects of Chromium(VI) on Constitutive and Inducible Gene Expression in Chick Embryo Liver In Vivo and Correlation With Chromium(VI)‐Induced DNA Damage

  1989cited by this paper
• Structure and expression of chicken metallothionein.

  1989cited by this paper
• The Ontogeny and Induction by Zinc of Hepatic Chick Embryo Metallothionein 1

  1988cited by this paper
• Heterogeneous DNA damage and repair in the mammalian genome.

  1987cited by this paper
• Inhibition of steroid-inducible tyrosine aminotransferase gene expression by N-methyl-N'-nitro-N-nitrosoguanidine in a rat hepatoma cell line.

  1986cited by this paper
• Cross-linking of cytokeratins to DNA in vivo by chromium salt and cis-diamminedichloroplatinum(II).

  1986cited by this paper
• Chromium (VI)-induced DNA damage in chick embryo liver and blood cells in vivo.

  1986cited by this paper
• Binding of chromium to chromatin and DNA from liver and kidney of rats treated with sodium dichromate and chromium(III) chloride in vivo.

  1985cited by this paper
• Chromium-induced cross-linking of nuclear proteins and DNA.

  1985cited by this paper
• Changes in hepatic levels of tyrosine aminotransferase messenger RNA during chemical hepatocarcinogenesis.

  1984cited by this paper
• Development of basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in the chicken embryo in ovo.

  1983cited by this paper
• The development of mixed function amine oxidase in cultured foetal rat hepatocytes and its relation to 3'-methyl-4-N,N-dimethylaminoazobenzene effects on tyrosine aminotransferase accumulation.

  1983cited by this paper
• Effects of carcinogens on hormonal regulation of gene expression in primary cultures of adult rat hepatocytes.

  1983cited by this paper
• Chromium(VI)-induced DNA lesions and chromium distribution in rat kidney, liver, and lung.

  1983cited by this paper
• Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues.

  1982cited by this paper
• Comparison of metallothionein determination by polarographic and cadmium-saturation methods.

  1982cited by this paper
• Aflatoxin inhibition of glucocorticoid finding capacity of rat liver nuclei.

  1976cited by this paper
• Effect of hepatocarcinogens on the binding of glucocorticoid-receptor complex in rat liver nuclei.

  1976cited by this paper
• Inhibition by aflatonin B-1 of hydrocortisone induction of rat liver tryptophan pyrrolase and tyrosine transaminase.

  1968cited by this paper

• A Novel Transcriptome Integrated Network Approach Identifies the Key Driver lncRNA Involved in Cell Cycle With Chromium (VI)-Treated BEAS-2B Cells

  2021cites this paper
• Can the effects of chromium compounds exposure be modulated by vitamins and microelements?

  2021cites this paper
• Toxicity of heavy metals in plants and animals and their uptake by magnetic iron oxide nanoparticles

  2020cites this paper
• Chromium (VI)-induced transformation is enhanced by Zn deficiency in BALB/c 3T3 cells.

  2015cites this paper
• Thread Embedding Acupuncture Inhibits Ultraviolet B Irradiation-Induced Skin Photoaging in Hairless Mice

  2015cites this paper
• Toxicological Profile for Chromium

  2012cites this paper
• Environmental toxicant exposure and the epigenome

  2012cites this paper
• Long-term exposure to hexavalent chromium inhibits expression of tumor suppressor genes in cultured cells and in mice.

  2012cites this paper
• Chromium (VI) inhibits mouse metallothionein-I gene transcription by modifying the transcription potential of the co-activator p300.

  2011cites this paper
• Chromium(VI) causes down regulation of biotinidase in human bronchial epithelial cells by modifications of histone acetylation.

  2011cites this paper
• Molecular Mechanisms of Zinc-mediated Induction and Chromium(VI)-mediated Inhibition of Mouse Metallothionein-I Gene Transcription

  2010cites this paper
• Hexavalent chromium exposure , genomic instability and lung cancer

  2008cites this paper
• Chromium(VI) inhibits mouse metallothionein-I gene transcription by preventing the zinc-dependent formation of an MTF-1-p300 complex.

  2008cites this paper
• The Journal of Toxicological Sciences

  2008cites this paper
• [Molecular mechanism involved in chromium(VI) toxicity].

  2008cites this paper
• Chromium Cross-Links Histone Deacetylase 1-DNA Methyltransferase 1 Complexes to Chromatin, Inhibiting Histone-Remodeling Marks Critical for Transcriptional Activation

  2007cites this paper
• 亜鉛応答性転写因子MTF-1とCr（VI）毒性 —6価クロムの発がん性と遺伝子発現抑制作用との関係—

  2007cites this paper
• Chromium Inhibits Transcription from Polycyclic Aromatic Hydrocarbon-inducible Promoters by Blocking the Release of Histone Deacetylase and Preventing the Binding of p300 to Chromatin*

  2004cites this paper
• Mechanisms of chromium-induced suppression of RNA synthesis in cellular and cell-free systems: Relationship to RNA polymerase arrest

  2004cites this paper
• Complexities of chromium carcinogenesis: role of cellular response, repair and recovery mechanisms.

  2003cites this paper
• Mitogen-Activated Protein Kinase Activation in UV-Induced Signal Transduction

  2003cites this paper
• Induction of p53 expression in skin by radiotherapy and UV radiation: a randomized study.

  2001cites this paper
• The tumor suppressor candidate p33(ING1) mediates repair of UV-damaged DNA.

  2001cites this paper
• Disruption of dioxin‐inducible phase I and phase II gene expression patterns by cadmium, chromium, and arsenic

  2000cites this paper
• Stimulatory effect of oral administration of green tea or caffeine on ultraviolet light-induced increases in epidermal wild-type p53, p21(WAF1/CIP1), and apoptotic sunburn cells in SKH-1 mice.

  2000cites this paper
• Down-regulation of p63 is required for epidermal UV-B-induced apoptosis.

  2000cites this paper
• The influence of chromium compounds on yeast physiology (a review).

  2000cites this paper
• Biological phenotype and coreceptor usage of human immunodeficiency virus (a short review).

  2000cites this paper
• Inhibition of protein synthesis by chromium(VI) differentially affects expression of urokinase and its receptor in human type II pneumocytes.

  1999cites this paper
• Differential effects of arsenic(III) and chromium(VI) on nuclear transcription factor binding

  1999cites this paper
• Developmentally specific effects of the DNA cross‐linking agent mitomycin C on phosphoenolpyruvate carboxykinase gene expression in vivo: Correlation with changes in chromatin structure within the promoter region of the gene

  1998cites this paper
• Cadmium suppresses apoptosis induced by chromium.

  1998cites this paper
• Molecular basis for effects of carcinogenic heavy metals on inducible gene expression.

  1998cites this paper
• Effects of the genotoxic carcinogen chromium(VI) on basal and hormone‐inducible phosphoenolpyruvate carboxykinase gene expression in vivo: Correlation with glucocorticoid‐and developmentally regulated expression

  1994cites this paper