A dual role for substrate S-adenosyl-L-methionine in the methylation reaction with bacteriophage T4 Dam DNA-[N6-adenine]-methyltransferase.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Nucleic Acids Research

• Publication date

  2001-06-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1093/NAR/29.11.2361PMID 11376154PMCID PMC55703
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structure of the N6-adenine DNA methyltransferase M•TaqI in complex with DNA and a cofactor analog

  2001cited by this paper
• Pre-steady state kinetics of bacteriophage T4 dam DNA-[N(6)-adenine] methyltransferase: interaction with native (GATC) or modified sites.

  2000influential reference
• Structure of RsrI methyltransferase, a member of the N6-adenine beta class of DNA methyltransferases.

  2000cited by this paper
• Functional Roles of the Conserved Threonine 250 in the Target Recognition Domain of HhaI DNA Methyltransferase*

  2000cited by this paper
• Reconciling Structure and Function in HhaI DNA Cytosine-C-5 Methyltransferase*

  2000cited by this paper
• Substrate binding in vitro and kinetics of RsrI [N6-adenine] DNA methyltransferase.

  2000cited by this paper
• Mechanism of inhibition of DNA (cytosine C5)-methyltransferases by oligodeoxyribonucleotides containing 5,6-dihydro-5-azacytosine.

  1999cited by this paper
• Mutational analysis of target base flipping by the EcoRV adenine-N6 DNA methyltransferase.

  1999cited by this paper
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  1999cited by this paper
• Effect of base analog substitutions in the specific GATC site on binding and methylation of oligonucleotide duplexes by the bacteriophage T4 Dam DNA-[N6-adenine] methyltransferase.

  1999cited by this paper
• Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base

  1998cited by this paper
• Chemical display of thymine residues flipped out by DNA methyltransferases.

  1998cited by this paper
• Direct Real Time Observation of Base Flipping by theEcoRI DNA Methyltransferase*

  1998cited by this paper
• 2-Aminopurine as a fluorescent probe for DNA base flipping by methyltransferases.

  1998cited by this paper
• Crystal structure of the DpnM DNA adenine methyltransferase from the DpnII restriction system of streptococcus pneumoniae bound to S-adenosylmethionine.

  1998cited by this paper
• Dam Methyltransferase from Escherichia coli: Kinetic Studies Using Modified DNA Oligomers: Nonmethylated Substrates

  1997cited by this paper
• FLUORESCENCE QUENCHING STUDY OF EQUILIBRIUM BINDING OF PHAGE T4 DAM DNA-N6-ADEHINE-METHYITRANSTERASE WITH SUBSTRATES AND LIGANDS

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• Structure of pvu II DNA-(cytosine N4) methyltransferase, an example of domain permutation and protein fold assignment.

  1997cited by this paper
• Interaction of the phage T4 Dam DNA-[N6-adenine] methyltransferase with oligonucleotides containing native or modified (defective) recognition sites.

  1997influential reference
• DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase.

  1997cited by this paper
• [Study of the equilibrium interaction of DAM-DNA-(N-adenine)-methyltransferase from phage T4 with substrates and ligands by fluorescence quenching].

  1997cited by this paper
• A structural basis for the preferential binding of hemimethylated DNA by HhaI DNA methyltransferase.

  1996cited by this paper
• Targeted base stacking disruption by the EcoRI DNA methyltransferase.

  1996cited by this paper
• Structure and function of DNA methyltransferases.

  1995cited by this paper
• HhaI and HpaII DNA methyltransferases bind DNA mismatches, methylate uracil and block DNA repair.

  1995cited by this paper
• Sequence-specific binding of DNA by the EcoRV restriction and modification enzymes with nucleic acid and cofactor analogues.

  1995cited by this paper
• Phage T4 DNA [N]-adenine6Methyltransferase. OVEREXPRESSION, PURIFICATION, AND CHARACTERIZATION (*)

  1995cited by this paper
• The crystal structure of Haelll methyltransferase covalently complexed to DNA: An extrahelical cytosine and rearranged base pairing

  1995cited by this paper
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  1994cited by this paper
• Hhal methyltransferase flips its target base out of the DNA helix

  1994cited by this paper
• Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine.

  1993cited by this paper
• Crystal structure of the HhaI DNA methyltransferase.

  1993cited by this paper
• Crystal-Structure of the Hhal DNA Methyltransferase Complexed with S-Adenosyl-L-Methionine

  1993cited by this paper
• Sequence-specific DNA binding by the MspI DNA methyltransferase.

  1992cited by this paper
• LAC9 DNA-binding domain coordinates two zinc atoms per monomer and contacts DNA as a dimer.

  1990cited by this paper
• The double role of methyl donor and allosteric effector of S-adenosyl-methionine for Dam methylase of E. coli.

  1990cited by this paper
• Calculation of protein extinction coefficients from amino acid sequence data.

  1989cited by this paper
• The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite.

  1989cited by this paper
• Kinetic and catalytic mechanism of HhaI methyltransferase.

  1987cited by this paper
• Enzyme structure and mechanism (2nd edn): by Alan Fersht, W. H. Freeman & Co., 1985. £14.95 pbk, £28.95 hbk (xxi + 475 pages) ISBN 0 7167 1615 1

  1985cited by this paper
• Molecular cloning of a functional dam+ gene coding for phage T4 DNA adenine methylase.

  1983cited by this paper
• Enzyme structure and mechanism

  1977cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper

• Distal structural elements coordinate a conserved base flipping network.

  2013cites this paper
• Using the fluorescence decay of 2-aminopurine to investigate conformational change in the recognition sequence of the EcoRV DNA-(adenine-N6)-methyltransferase on enzyme binding.

  2012cites this paper
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  2012cites this paper
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  2011cites this paper
• Use of green fluorescent protein for the analysis of protein-protein and protein-DNA interactions

  2011cites this paper
• Diversity of DNA methyltransferases that recognize asymmetric target sequences

  2010cites this paper
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• Coronaviral 2’-O-Methyltransferase Function in Virus Replication.

  2009cites this paper
• Dimeric/oligomeric DNA methyltransferases: an unfinished story

  2009cites this paper
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  2009cites this paper
• DNA base flipping by both members of the PspGI restriction–modification system

  2008cites this paper
• Study of Bacteriophage T4-encoded Dam DNA (Adenine-N6)-methyltransferase Binding with Substrates by Rapid Laser UV Cross-linking*

  2007cites this paper
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  2007cites this paper
• VILNIUS UNIVERSITY

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  2007cites this paper
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  2007cites this paper
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