Possible mechanism for the biological action of lithium

No abstract is available for this paper.

• Publication year

  1976

• Venue

  Nature

• Publication date

  1976-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1038/263237a0PMID 958476
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Lithium-nucleotide interactions investigated by gel filtration.

  1975cited by this paper
• LITHIUM AND MAGNESIUM-DEPENDENT ENZYMES

  1974cited by this paper
• Letter: The role of magnesium and calcium in the pharmacology of lithium.

  1973cited by this paper
• Crystallography of a metal-containing protein, concanavalin A.

  1973cited by this paper
• Myokinase equilibrium. An enzymatic method for the determination of stability constants of magnesium complexes with adenosine triphosphate, adenosine diphosphate, and adenosine monophosphate in media of high ionic strength.

  1973cited by this paper
• The distribution of lithium and its effects on the distribution and excretion of other ions in the rat

  1973cited by this paper
• Cation and cavity selectivities of alkali and alkaline-earth “cryptates”

  1971cited by this paper
• Effects of Lithium on Plasma Magnesium

  1970cited by this paper
• Distribution of Metals and Catecholamines in Bovine Adrenal Medulla Sub-Cellular Fractions

  1965cited by this paper
• 70. The stabilities of complexes of uramildiacetic acid and its homologues

  1963cited by this paper
• METAL CHELATES OF ADENOSINE TRIPHOSPHATE1

  1962cited by this paper
• Suggestions for the treatment of schizophrenic and manic-depressive patients.

  1955cited by this paper

• ATP Can Act as a Stabilizer on Neutral Macromolecules

  2025cites this paper
• Intracellular Effects of Lithium in Aging Neurons.

  2024cites this paper
• A Genome-Wide Screen in Saccharomyces cerevisiae Reveals a Critical Role for Oxidative Phosphorylation in Cellular Tolerance to Lithium Hexafluorophosphate

  2021cites this paper
• From intracellular signaling pathways to neural circuit dysfunction in bipolar disorder

  2021cites this paper
• Trinuclear Calcium Site in the C2 Domain of PKCα/γ Is Prone to Lithium Attack

  2021cites this paper
• Biomass of Arthrospira platensis enriched with lithium by bioaccumulation and biosorption process

  2021cites this paper
• Current understanding of bipolar disorder: Toward integration of biological basis and treatment strategies

  2019cites this paper
• How Native and Non-Native Cations Bind and Modulate the Properties of GTP/ATP.

  2018cites this paper
• Personalized Medicine and Resurrected Hopes for the Management of Alzheimer's Disease: A Modular Approach Based on GSK-3β Inhibitors.

  2017cites this paper
• How Native and Alien Metal Cations Bind ATP: Implications for Lithium as a Therapeutic Agent

  2017cites this paper
• Is lithium biologically an important or toxic element to living organisms? An overview

  2016cites this paper
• Lithium in Medicine: Mechanisms of Action.

  2016cites this paper
• A Molecular Model for Lithium's Bioactive Form.

  2016cites this paper
• Exploration of Lithium Ion Binding to Magnesium Bound Adenosine Triphosphate and Its Implications for Bipolar Disorder

  2015cites this paper
• Efeitos do lítio sobre a expressão e atividade das enzimas fosfolipase A2 e glicogênio sintase quinase 3beta e sua relação com o estado de fosforilação da proteína tau

  2015cites this paper
• Calcium dysregulation, and lithium treatment to forestall Alzheimer's disease - a merging of hypotheses.

  2014cites this paper
• Treatment of trauma with lithium to forestall the development of posttraumatic stress disorder by pharmacological induction of a mild transient amnesia.

  2013cites this paper
• Multiscale approaches and perspectives to modeling aqueous electrolytes and polyelectrolytes.

  2012cites this paper
• Lithium and Medicine: Inorganic Pharmacology

  2010cites this paper
• Intracellular pathways underlying the effects of lithium

  2010cites this paper
• On the mechanism of inhibition of rat fat cell adenylate cyclase by lithium.

  2009cites this paper
• Lone pair versus bonding pair electrons: the mechanism of electronic polarization of water in the presence of positive ions.

  2008cites this paper
• Identification of Li(+) binding sites and the effect of Li(+) treatment on phospholipid composition in human neuroblastoma cells: a (7)Li and (31)P NMR study.

  2005cites this paper
• Intracellular lithium and cyclic AMP levels are mutually regulated in neuronal cells

  2004cites this paper
• Changes in blood plasma osmolality and states of mania

  2004cites this paper
• Biochemical and psychiatric predictors of Li(+) response and toxicity in Li(+)-treated bipolar patients.

  2004cites this paper
• Effect of chronic Li+ treatment on free intracellular Mg2+ in human neuroblastoma SH-SY5Y cells.

  2003cites this paper
• Testing competing path models linking the biochemical variables in red blood cells from Li+-treated bipolar patients.

  2003cites this paper
• Effect of lithium on granulopolesis in culture

  2001cites this paper
• Li+/Mg2+ competition at therapeutic intracellular Li+ levels in human neuroblastoma SH-SY5Y cells.

  2000cites this paper
• Lithium induced changes in intracellular free magnesium concentration in isolated rat ventricular myocytes

  1999cites this paper
• Competition between Li+ and Mg2+ in neuroblastoma SH-SY5Y cells: a fluorescence and 31P NMR study.

  1999cites this paper
• Der Zelltransport und die inorganische Biochemie von Lithium

  1997cites this paper
• The inhibitory effect of Li+ on contractile elements of intestinal smooth muscle.

  1995cites this paper
• Competition between Li+ and Mg2+ for the phosphate groups in the human erythrocyte membrane and ATP: an NMR and fluorescence study.

  1994cites this paper
• Lithium Binding to Human RBC Membranes and Substrates of Second Messenger Systems

  1994influential citation
• Competition of Li(I) and Mg(II) for ATP binding: a 31P NMR study.

  1993cites this paper
• Accumulation and intracellular compartmentation of lithium ions in Saccharomyces cerevisiae.

  1993cites this paper
• Le lithium, ses effets et ses modes d'action possibles chez les végétaux

  1993cites this paper
• Lithium Transport, Mg2+ Competition, and Phospholipid Composition in Human Erythrocytes: A Multinuclear Magnetic Resonance Study

  1992cites this paper
• 9 – Lithium in the Cellular Environment

  1991cites this paper
• Application of 2D7Li NMR exchange spectroscopy to the kinetic study of the complex (lithium-monobenzo-15-crown-5)+ in solution

  1991cites this paper
• Competition between Li+ and Mg2+ for ATP and ADP in aqueous solution: a multinuclear NMR study.

  1991cites this paper
• 23Na and 7Li NMR Studies of Mammalian Cells: Assessment of Cation Transport and Cytoskeletal Structure with Application to Manic Depressive Disease

  1990cites this paper
• Some Aspects of Lithium in Living Systems

  1990cites this paper
• Competition between Li+ and Mg2+ for ATP in human erythrocytes A 31P NMR and optical spectroscopy study

  1989cites this paper
• Platelets and neurobiological research

  1988cites this paper
• Influence of the protonation degree on the self-association properties of adenosine 5'-triphosphate (ATP).

  1988cites this paper
• 7Li NMR study of normal human erythrocytes

  1987cites this paper
• Biological effects of lithium: Experimental analysis in plant cytokinesis

  1987cites this paper
• 7Li‐NMR Study of Human Erythrocytes a

  1987cites this paper
• Self-association of adenosine 5'-monophosphate (5'-AMP) as a function of pH and in comparison with adenosine, 2'-AMP and 3'-AMP.

  1987cites this paper
• Isomeric equilibria in complexes of adenosine 5'-triphosphate with divalent metal ions. Solution structures of M(ATP)2- complexes.

  1987cites this paper
• Pharmacokinetics of lithium in the dog.

  1986cites this paper
• Calcium antagonists in mania: a double-blind study of verapamil.

  1986cites this paper
• A potentiometric study of lithium complexation with catecholamines.

  1986cites this paper
• Phenelzine-induced hypomania: effect of verapamil.

  1985cites this paper
• Lithium reversibly inhibits microtubule-based motility in sperm flagella

  1984cites this paper
• Lithium interferes with reserpine‐induced dopamine depletion

  1983cites this paper
• Lithium attenuates dopamine depleting effects of reserpine and tetrabenazine but not that of alpha methyl-p-tyrosine.

  1983cites this paper
• Some observations on the behaviour of the sodium efflux in barnacle muscle fibres towards lithium ions.

  1983cites this paper
• Interactions of monovalent cations with phosphatidylserine bilayer membranes.

  1983cites this paper
• Lithium: Grundlagen und Therapie

  1983cites this paper
• Behavioral and biochemical changes induced by lithium and L-tryptophan in muricidal rats.

  1982cites this paper
• Preferential accumulation of lithium in the dense bodies of human platelets.

  1982cites this paper
• Effects of Li-substitution on high-K induced contractions of various smooth muscle tissues in the guinea-pig.

  1982cites this paper
• Inhibition by lithium of PGE1-sensitive adenylate cyclase in neuroblastoma X glioma hybrid cells: approach to the attenuation of the opiate withdrawal syndrome.

  1982cites this paper
• Thermodynamic studies on mixed complexes-I Complexes of uramildiacetic acid and of nitrilotriacetic acid with transition metals and glycine

  1981cites this paper
• NMR studies of the complexes of uramildiacetic acid

  1981cites this paper
• Observations on ADP aggregation of lithium chloride incubated platelets in a variety of mammalian species.

  1980cites this paper
• Membrane Models for Circadian Rhythms

  1980cites this paper
• The effect of lithium carbonate on lymphocyte, granulocyte, and platelet function

  1980cites this paper
• The bactericidal defect of neutrophil function with lithium therapy.

  1980cites this paper
• Long-term effect of lithium on the uptake of 5-hydroxytryptamine by human platelets.

  1980cites this paper
• Magnesium in mental illness.

  1979cites this paper
• TRACE METALS IN THE HUMAN CONTEXT

  1979cites this paper
• A proton nuclear-magnetic-resonance study of self-stacking in purine and pyrimidine nucleosides and nucleotides.

  1978cites this paper
• Effect of lithium on granulopoiesis in culture.

  1978cites this paper
• Evidence for anionic cation transport of lithium, sodium and potassium across the human erythrocyte membrane induced by divalent anions.

  1978cites this paper
• The influence of lithium and calcium ions on the aggregation of human blood platelets.

  1978cites this paper
• Mineral springs and spring fever. Lithium: fact and fantasy in psychopharmacology.

  1978cites this paper
• POLARITIES, CELL DIFFERENTIATION AND PRIMARY INDUCTION IN THE AMPHIBIAN EMBRYO

  1978cites this paper
• Growth of heat-injured Vibrio parahaemolyticus in media supplemented with various cations

  1977cites this paper
• Lithium therapy and alkaline earth metal metabolism: a biochemical screening study

  1977cites this paper
• Plasma aldosterone and magnesium in serum and urine during lithium treatment.

  1977cites this paper
• Possible mechanism for biological action of lithium

  1976cites this paper