Studies on the mechanism of action of hexamethylene bisacetamide, a potent inducer of erythroleukemic differentiation.

No abstract is available for this paper.

• Publication year

  1979

• Venue

  Biochimica et Biophysica Acta

• Publication date

  1979-12-11

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/0304-4165(79)90339-8PMID 292456
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Effects of hexamethylenebisacetamide on the differentiation of embryonal carcinoma cells].

  1978cited by this paper
• Induction of murine erythroleukemia differentiation by actinomycin D.

  1978cited by this paper
• Erythroleukemic differentiation.

  1978cited by this paper
• Inducers of erythroleukemic differentiation. Relationship of structure to activity among planar-polar compounds.

  1978cited by this paper
• Accumulation of α- and β-globin messenger RNAs in mouse erythroleukemia cells

  1977cited by this paper
• Accumulation of alpha- and beta-globin messenger RNAs in mouse erythroleukemia cells.

  1977cited by this paper
• Induction of spectrin in erythroleukemic cells transformed by Friend virus.

  1977cited by this paper
• Hexamethylene bisacetamide induces morphologic changes and increased synthesis of procollagen in cell line from glioblastoma multiforme.

  1977cited by this paper
• Effect of hexamethylene bisacetamide on the commitment to differentiation of murine erythroleukemia cells.

  1977cited by this paper
• Differential effects of chemical inducers on expression of beta globin genes in murine erythroleukemia cells.

  1977cited by this paper
• Induction of differentiation in mouse neuroblastoma cells by hexamethylene bisacetamide.

  1977cited by this paper
• Induction of globin mRNA accumulation by hemin in cultured erythroleukemic cells.

  1976cited by this paper
• Induction by ouabain of hemoglobin synthesis in cultured Friend erythroleukemic cells.

  1976cited by this paper
• Commitment to erythroid differentiation by friend erythroleukemia cells: a stochastic analysis.

  1976cited by this paper
• A new group of potent inducers of differentiation in murine erythroleukemia cells.

  1976cited by this paper
• Induction of erythroid differentiation in vitro by purines and purine analogues.

  1976cited by this paper
• Sequential induction of heme pathway enzymes during erythroid differentiation of mouse Friend leukemia virus-infected cells

  1976cited by this paper
• Induction of erythroid differentiation by dimethylsulfoxide in cells infected with Friend virus: relationship to the cell cycle.

  1975cited by this paper
• Induction of erythroid differentiation in murine virus infected eythroleukemia cells by highly polar compounds.

  1975cited by this paper
• Differential expression of alpha- and beta-globin genes during differentiation of cultured erythroleukemic cells.

  1975cited by this paper
• Differentiation of cultured Friend leukemia cells induced by short-chain fatty acids.

  1975cited by this paper
• Differentiation of erythroleukemia cells in vitro: properties of chemical inducers.

  1975cited by this paper
• Butyric acid, a potent inducer of erythroid differentiation in cultured erythroleukemic cells.

  1975cited by this paper
• Globin gene expression in cultured erythroleukemic cells.

  1974cited by this paper
• Erythropoietic differentiation in colonies of cells transformed by Friend virus.

  1974cited by this paper
• Induction of Δ-Aminolevulinic Acid Synthetase During Erythroid Differentiation of Cultured Leukemia Cells

  1974cited by this paper
• Hemoglobin biosynthesis in murine virus-induced leukemic cells in vitro: structure and amounts of globin chains produced.

  1972cited by this paper
• Synthesis of mouse haemoglobin and globin mRNA in leukaemic cell cultures.

  1972cited by this paper
• Globin messenger-RNA induction during erythroid differentiation of cultured leukemia cells.

  1972cited by this paper
• Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide.

  1971cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Synthesis of minoxidil conjugates and their evaluation as HL-60 differentiation agents.

  2016cites this paper
• Hexamethylene bisacetamide can convert nonpermissive human cells to a permissive state for expressing the major immediate-early genes of human cytomegalovirus by up-regulating NF-kappaB activity.

  2009cites this paper
• Aus der Medizinischen Universitätsklinik und

  2005cites this paper
• Salivary concentrations of hexamethylene bisacetamide (HMBA) in patients receiving 5-day continuous infusions

  2004cites this paper
• Approaches to optimal dosing of hexamethylene bisacetamide

  2004cites this paper
• The effect of the monoamine oxidase inhibitor isocarboxazid on the canine metabolism of the cell-differentiating agent hexamethylene bisacetamide

  2004cites this paper
• Hexamethylene Bisacetamide (HMBA) Increases Thyroglobulin Levels in Porcine Thyroid Cells Without Increasing Cyclic-AMP

  1999cites this paper
• Hexamethylene bisacetamide (HMBA) increases thyroglobulin levels in porcine thyroid cells without increasing cyclic-AMP.

  1999cites this paper
• Amplification of the expression of major histocompatibility class-I antigens by inducers of differentiation and gamma interferon in murine and human solid tumor-cell lines.

  1993cites this paper
• Changes in gene expression following exposure of nulli-SCCl murine embryonal carcinoma cells to inducers of differentiation: characterization of a down-regulated mRNA.

  1991cites this paper
• Effect of hexamethylene bisacetamide and cyclosporin A on recovery of herpes simplex virus type 2 from the in vitro model of latency in a human neuroblastoma cell line.

  1990cites this paper
• Modification of transformation of C3H/10T1/2 cells by a differentiation-inducing substance.

  1990cites this paper
• Effects of the monoamine oxidase inhibitor, tranylcypromine, on induction of HL60 cell differentiation by hexamethylene bisacetamide and N-acetyl-1,6-diaminohexane.

  1990cites this paper
• Chemical inducers of differentiation in a long-term renal cell line.

  1989cites this paper
• Phase I trial using adaptive control dosing of hexamethylene bisacetamide (NSC 95580).

  1989cites this paper
• Metabolism of new anticancer agents.

  1989cites this paper
• Involvement of monoamine oxidase and diamine oxidase in the metabolism of the cell differentiating agent hexamethylene bisacetamide (HMBA).

  1988cites this paper
• Induction of differentiation of human promyelocytic leukemia cells (HL60) by metabolites of hexamethylene bisacetamide.

  1988cites this paper
• Metabolism of hexamethylene bisacetamide and its metabolites in leukemic cells.

  1988cites this paper
• Phase I clinical and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered as a five-day continuous infusion.

  1987influential citation
• Plasma pharmacokinetics and urinary excretion of hexamethylene bisacetamide metabolites.

  1987cites this paper
• Gas chromatographic analysis of metabolites of the cell differentiating agent hexamethylene bisacetamide.

  1987cites this paper
• Identification of metabolites of the cell-differentiating agent hexamethylene bisacetamide in humans.

  1986cites this paper
• Catabolites produced by the deacetylation of hexamethylenebisacetamide play a key role in murine erythroleukaemic-cell differentiation.

  1986cites this paper
• Hexamethylene bisacetamide: a polar-planar compound entering clinical trials as a differentiating agent.

  1986cites this paper
• Differentiation factors.

  1986cites this paper
• Inducer-dependent phenotypic divergence in an embryonal-carcinoma cell line.

  1984cites this paper
• Acetylated diamines inhibit endotoxin-induced lymphocyte activation.

  1984cites this paper
• Differentiation-defective mutants of mouse embryonal carcinoma cells: response to hexamethylenebisacetamide and retinoic acid.

  1983cites this paper
• Effects of hexamethylene bisacetamide onα-fetoprotein, albumin, and transferrin production by two rat hepatoma cell lines

  1982cites this paper
• Links Between Effects of Butyrate on Histone Hyperacetylation and Regulation of Interferon Synthesis in Namalva and FS-4 Cell Lines

  1982cites this paper
• Enhancement of polyethylene glycol-mediated cell hybridization by inducers of erythroleukemia cell differentiation

  1982cites this paper
• Chicken fetal and adult antigen expression on erythroleukemia cells before and after induced differentiation.

  1982cites this paper
• Erythroid differentiation and commitment in rat erythroleukemia cells with hypertonic culture conditions.

  1981cites this paper
• Chemically induced murine erythroleukemic differentiation.

  1980cites this paper