Mutation screening and association studies of the human uncoupling protein 3 gene in normoglycemic and diabetic morbidly obese patients.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Diabetes

• Publication date

  1999-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.2337/diabetes.48.1.206PMID 9892245
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1998cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1995cited by this paper
• A sequence related to a DNA recognition element is essential for the inhibition by nucleotides of proton transport through the mitochondrial uncoupling protein.

  1994cited by this paper
• Analysis of uncoupling protein and its mRNA in adipose tissue deposits of adult humans.

  1992cited by this paper
• Mechanism and evolution of the uncoupling protein of brown adipose tissue.

  1990cited by this paper
• Thermogenic mechanisms in brown fat.

  1984cited by this paper

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  2020cites this paper
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  2015cites this paper
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  2011cites this paper
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  2008cites this paper
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  2007cites this paper
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  2007cites this paper
• The energetic implications of uncoupling protein-3 in skeletal muscle.

  2007cites this paper
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  2006cites this paper
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  2006cites this paper
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  2004cites this paper
• The human obesity gene map: the 2003 update.

  2004cites this paper
• Uncoupling Proteins : Regulation by IGF-1 and Neuroprotection during Hyperglycemia in Vitro

  2004cites this paper
• [Obesity studies in candidate genes].

  2004cites this paper
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  2004cites this paper
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  2004cites this paper
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  2003cites this paper
• The human obesity gene map: the 2001 update.

  2002cites this paper
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• [Role of uncoupling proteins in obesity].

  2002cites this paper
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  2002cites this paper
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  2001cites this paper
• The human obesity gene map: the 2000 update.

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  2000cites this paper
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  2000cites this paper
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  year unknowncites this paper