Selective alteration at the growth‐hormone‐ releasing‐hormone nerve terminals during aging in GHRH‐green fluorescent protein mice

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Aging Cell

• Publication date

  2007-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1474-9726.2007.00276.xPMID 17328688
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1988cited by this paper
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