Pyridazine derivatives. XI: Antihypertensive activity of 3-hydrazinocycloheptyl[1,2-c]pyridazine and its hydrazone derivatives.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Journal of Pharmacy and Science

• Publication date

  1993-03-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1002/JPS.2600820314PMID 8450424
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differences in inositol phosphate production in blood vessels of normotensive and spontaneously hypertensive rats

  1991cited by this paper
• Increasing complexity revealed in regulation of Ca2+ antagonist receptor.

  1989cited by this paper
• Pyridazine Derivatives, VII. Synthesis and Hypotensive Activity of 3‐Hydrazinocycloalkyl[1,2‐c]pyridazines and their Derivatives

  1989cited by this paper
• Cellular mechanisms regulating [Ca2+]i smooth muscle.

  1989cited by this paper
• Vascular smooth muscle membrane in hypertension.

  1988cited by this paper
• Pyridazine Derivatives, VI . Synthesis and Hypotensive Activity of 3‐Hydrazinethieno(2,3‐h)Cinnoline and its Derivatives

  1988cited by this paper
• In vitro kinetic studies of the reaction of hydralazine and its acetone hydrazone with pyruvic acid.

  1988cited by this paper
• Hydralazine-relaxing effect on rat aorta is not mediated through changes in ATPase activity.

  1987cited by this paper
• Role of the sympatho-adrenal system in the reflex tachycardia produced by hydralazine in the anesthetized rat.

  1986cited by this paper
• Chlorosulfonyl Isocyanateian Unusual Chlorinating Agent

  1986cited by this paper
• Influence of the vascular endothelium on agonist‐induced contractions and relaxations in rat aorta

  1986cited by this paper
• Is calcium more important than sodium in the pathogenesis of essential hypertension?

  1985cited by this paper
• The role of protein kinase C in cell surface signal transduction and tumour promotion

  1984cited by this paper
• Mechanism of action of hydralazine on vascular smooth muscle.

  1984cited by this paper
• Differential effects of hydralazine on the biphasic responses of helical strips from rat tail arteries.

  1983cited by this paper
• The fifth scientific meeting of the interamerican society of hypertension, 1983

  1983cited by this paper
• Endothelial Mechanism in the Vascular Action of Hydralazine

  1983cited by this paper
• Endogenous generation of hydralazine from labile hydralazine hydrazones.

  1982cited by this paper
• In vitro differences between human arteries and veins in their responses to hydralazine.

  1981cited by this paper
• Antihypertensive effects of nifedipine on conscious normotensive and hypertensive rats.

  1981cited by this paper
• Regional blood flow and cardiac responses to hydralazine.

  1980cited by this paper
• Interaction of hydralazine with tension development and mechanisms of calcium accumulation in K+-stimulated rabbit aortic strips.

  1978cited by this paper
• COMPARATIVE EVALUATION OF THE in vitro EFFECTS OF HYDRALAZINE AND HYDRALAZINE ACETONIDE ON ARTERIAL SMOOTH MUSCLE

  1977cited by this paper
• Mechanisms of Action of Antiarrhythmic Drugs

  1973cited by this paper
• Blockade or reversal of the contraction induced by calcium and adrenaline in depolarized arterial smooth muscle

  1969cited by this paper
• Mechanism of tachycardia induced by intracerebroventricular injection of hydrallazine (1-hydrazinophthalazine).

  1965cited by this paper
• Hypotensive actions of drugs on unanesthetized normotensive and "metacorticoid" hypertensive rats determined by a direct recording technique.

  1965cited by this paper
• Neurogenic Hypertension in the Rat

  1964cited by this paper
• Development of a strain of spontaneously hypertensive rats.

  1963cited by this paper
• Hemodynamics of hypertension.

  1960cited by this paper
• [A new group of hypotensive substances with a special mechanism of action].

  1950cited by this paper
• A new method for the indirect measurement of blood pressure in the rat.

  1947cited by this paper

• Hydrazones derivatives from halo-pyridinol: synthesis and DFT-based theoretical exploration

  2025cites this paper
• Effective scaffolds as antihypertensive agents, a long story with happy endings; a review tracing the promising reported candidates

  2024cites this paper
• Computational molecular modelling of proline derivatives as ACE inhibitors

  2023cites this paper
• Application of Choline Chloride-Based Deep Eutectic Solvents in the Synthesis of Hydrazones

  2023cites this paper
• Focusing on New Piperazinyl‐methyl‐3(2H)pyridazinone Based Derivatives: Design, Synthesis, Anticancer Activity and Computational Studies

  2023cites this paper
• Mechanochemical Studies on Coupling of Hydrazines and Hydrazine Amides with Phenolic and Furanyl Aldehydes—Hydrazones with Antileishmanial and Antibacterial Activities

  2023cites this paper
• Non-covalent interactions abetted supramolecular arrangements of N-Substituted benzylidene acetohydrazide to direct its solid-state network

  2021cites this paper
• Biologically Active Pyridazines and Pyridazinone Derivatives: A Scaffold for the Highly Functionalized Compounds

  2020cites this paper
• Synthesis and biological screening of some novel 6‐substituted 2‐alkylpyridazin‐3(2H)‐ones as anti‐inflammatory and analgesic agents

  2020cites this paper
• An Experimental and Computational Exploration on the Electronic, Spectroscopic, and Reactivity Properties of Novel Halo-Functionalized Hydrazones

  2020cites this paper
• Green Synthesis, SC-XRD, Non-Covalent Interactive Potential and Electronic Communication via DFT Exploration of Pyridine-Based Hydrazone

  2020cites this paper
• Novel ionic liquids incorporated pyridazinone-vanillyl motifs: Synthesis, characterization, pharmacological survey and molecular docking

  2018cites this paper
• Pyridazinone hybrids: Design, synthesis and evaluation as potential anticonvulsant agents.

  2018cites this paper
• Convenient Synthesis of Some Novel Pyridazinone‐Bearing Triazole Moieties

  2018cites this paper
• SYNTHESIS, CHARACTERIZATION, AND PHARMACOLOGICAL EVALUATION OF SOME NOVEL HYDRAZONE DERIVATIVES DERIVED FROM 3-((4-FORMYL-2- METHOXYPHENOXY) METHYL) BENZONITRILE

  2016cites this paper
• The therapeutic journey of pyridazinone.

  2016cites this paper
• New pyrano[2,3-c]pyridazine derivatives with antimicrobial activity synthesized using piperidine as the organocatalyst

  2015cites this paper
• Radical mediated C-H functionalization of 3,6-dichloropyridazine: efficient access to novel tetrahydropyridopyridazines.

  2015cites this paper
• One-Pot Synthesis of Novel 2-(Thiazol-2-yl)-4,5-dihydropyridazin-3(2H)-one Derivatives Catalyzed by Activated KSF

  2014cites this paper
• Prediction of antihypertensive activity of pyridazinone derivatives through multivariate image analysis applied to QSAR

  2013cites this paper
• Synthesis and in vitro Biological Activity of New 4,6-Disubstituted 3(2H)-Pyridazinone-acetohydrazide Derivatives

  2012cites this paper
• Design, synthesis and antiviral activity of novel pyridazines.

  2012cites this paper
• Synthesis and evaluation of anticancer activity of some novel 6-aryl-2-(p-sulfamylphenyl)-pyridazin-3(2H)-ones.

  2012cites this paper
• Triazole incorporated pyridazinones as a new class of antihypertensive agents: design, synthesis and in vivo screening.

  2011cites this paper
• Synthesis, characterization and antihypertensive activity of pyridazinone derivatives.

  2010cites this paper
• 6-Phenyl-2-(4-phenyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)-4,5-dihydropyridazin-3(2H)-one

  2010cites this paper
• Screening and evaluation of antioxidant activity of some pyridazine derivatives

  2008cites this paper
• Microwave‐Assisted Synthesis and Antiprotozoal Activity of Pyridazines Carrying Polyfluoro Substituents

  2006cites this paper
• In vivo and in vitro pharmacological studies of a new hypotensive compound (QF0301B) in rat: comparison with prazosin, a known alpha1-adrenoceptor antagonist.

  2003cites this paper
• Synthesis and anticonvulsant activity of novel 1-substituted-1,2-dihydro-pyridazine-3,6-diones.

  2003cites this paper
• Preliminary Study of the Potential Vasodilator Effects on Rat Aorta of Centaurein and Centaureidin, Two Flavonoids from Centaurea corcubionensis

  1998cites this paper
• Pyridazine derivatives XIV. Study of the vasorelaxant action of 6-aryl-5-piperidino-3-hydrazinopyridazines in isolated rat thoracic aorta: comparison with hydralazine.

  1998cites this paper
• PYRIDAZINES. XV. SYNTHESIS OF 6-ARYL-5-AMINO-3(2H)-PYRIDAZINONES AS POTENTIAL PLATELET AGGREGATION INHIBITORS

  1998cites this paper
• Study of the in vivo and in vitro cardiovascular effects of a hydralazine‐like vasodilator agent (HPS‐10) in normotensive rats

  1997cites this paper
• Pyridazine Derivatives. Part 11. Antihypertensive Activity of 3- Hydrazinocyclohepta(1,2-c)pyridazine and Its Hydrazone Derivatives.

  1995cites this paper