The IL15 +96522 A>T functional polymorphism is related to the differentiation of Th17 cells and the severity of Hashimoto's disease

No abstract is available for this paper.

• Publication year

  2017

• Venue

  International Journal of Immunogenetics

• Publication date

  2017-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/iji.12305PMID 28164472
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Diseases

  2021cited by this paper
• Grave’s Disease

  2017cited by this paper
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• Relation of IL‐6, IL‐13 and IL‐15 gene polymorphisms to the rheumatoid factors, anti‐CCP and other measures of rheumatoid arthritis activity

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• The transcription factor T-bet is induced by IL-15 and thymic agonist selection and controls CD8αα(+) intraepithelial lymphocyte development.

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• Differentiation and function of Foxp3(+) effector regulatory T cells.

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• IL-15 Augments TCR-Induced CD4+ T Cell Expansion In Vitro by Inhibiting the Suppressive Function of CD25High CD4+ T Cells

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• CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game

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• Interleukin‐15 Induces Interleukin‐17 Production by Synovial T Cell Lines from Patients with Rheumatoid Arthritis

  2011cited by this paper
• Association of functional polymorphisms in promoter regions of IL5, IL6 and IL13 genes with development and prognosis of autoimmune thyroid diseases

  2011cited by this paper
• Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases.

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• Increased circulating pro-inflammatory cytokines and Th17 lymphocytes in Hashimoto's thyroiditis.

  2010cited by this paper
• Association of functional polymorphisms related to the transcriptional level of FOXP3 with prognosis of autoimmune thyroid diseases

  2010cited by this paper
• Monocytes differentiated with IL-15 support Th17 and Th1 responses to wheat gliadin: implications for celiac disease.

  2010cited by this paper
• Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.

  2009cited by this paper
• Association of the −31C/T functional polymorphism in the interleukin‐1β gene with the intractability of Graves' disease and the proportion of T helper type 17 cells

  2009cited by this paper
• Involvement of functional polymorphisms in the TNFA gene in the pathogenesis of autoimmune thyroid diseases and production of anti‐thyrotropin receptor antibody

  2009cited by this paper
• Increases of the Th1/Th2 Cell Ratio in Severe Hashimoto's Disease and in the Proportion of Th17 Cells in Intractable Graves' Disease

  2009cited by this paper
• The +869T/C polymorphism in the transforming growth factor‐β1 gene is associated with the severity and intractability of autoimmune thyroid disease

  2008cited by this paper
• The -590CC genotype in the IL4 gene as a strong predictive factor for the development of hypothyroidism in Hashimoto disease.

  2008cited by this paper
• IL‐15 acts as a potent inducer of CD4+CD25hi cells expressing FOXP3

  2008cited by this paper
• Apoptosis-induced Decrease of Intrathyroidal CD4+CD25+ Regulatory T Cells in Autoimmune Thyroid Diseases

  2007cited by this paper
• Polymorphisms in interleukin-15 gene on chromosome 4q31.2 are associated with psoriasis vulgaris in Chinese population.

  2007influential reference
• Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene.

  2006cited by this paper
• Lipopolysaccharide-Stimulated or Granulocyte-Macrophage Colony-Stimulating Factor-Stimulated Monocytes Rapidly Express Biologically Active IL-15 on Their Cell Surface Independent of New Protein Synthesis1 2

  2001cited by this paper
• Interleukin 15: biology and relevance to human disease.

  2001cited by this paper
• The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens.

  1999cited by this paper
• IL-15 promotes cytokine production of human T helper cells.

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• IL-15 has stimulatory activity for the induction of B cell proliferation and differentiation.

  1995cited by this paper
• Association of serum antithyroid antibodies with lymphocytic infiltration of the thyroid gland: studies of seventy autopsied cases.

  1978cited by this paper
• MEASURMENT OF CIRCULATING THYROID MICROSOMAL ANTIBODIES BY THE TANNED RED CELL HAEMAGGLUTINATION TECHNIQUE: ITS USEFULNESS IN THE DIAGNOSIS OF AUTOIMMUNE THYROID DISEASES

  1976cited by this paper

• Pathogenic role of Th17 cells in autoimmune thyroid disease and their underlying mechanisms.

  2023cites this paper
• Rs7537605 polymorphism in VAV3 gene and rs28665122 polymorphism in SEPS gene are not associated with Hashimoto's thyroiditis in North-East Algerian population

  2022cites this paper
• Genotype association of IP6K3 gene with Hashimoto’s thyroiditis in Algerian population (Aures region)

  2020cites this paper
• Associations Between Three CTLA-4 Polymorphisms and Hashimoto's Thyroiditis Risk: An Updated Meta-Analysis with Trial Sequential Analysis

  2018cites this paper