Age‐related increase in the total number of corticotropin‐releasing hormone neurons in the human paraventricular nucleus in controls and alzheimer's disease: Comparison of the disector with an unfolding method

No abstract is available for this paper.

• Publication year

  1994

• Venue

  The Journal of comparative neurology

• Publication date

  1994-01-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/cne.903390311PMID 8132871
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Increased Cortisol Levels in Aging and Alzheimer's Disease in Postmortem Cerebrospinal Fluid

  1994cited by this paper
• Effect of desipramine on cerebrospinal fluid concentrations of corticotropin-releasing factor in human subjects.

  1993cited by this paper
• Localization of corticotropin-releasing hormone (CRH) neurons in the paraventricular nucleus of the human hypothalamus; age-dependent colocalization with vasopressin.

  1993cited by this paper
• Chronic stress enhances vasopressin but not corticotropin-releasing factor secretion during hypoglycemia.

  1992cited by this paper
• Repeated stress enhances vasopressin synthesis in corticotropin releasing factor neurons in the paraventricular nucleus.

  1992cited by this paper
• The antidepressants fluoxetine, idazoxan and phenelzine alter corticotropin-releasing hormone and tyrosine hydroxylase mRNA levels in rat brain: therapeutic implications.

  1992cited by this paper
• Long-term antidepressant administration alters corticotropin-releasing hormone, tyrosine hydroxylase, and mineralocorticoid receptor gene expression in rat brain. Therapeutic implications.

  1991cited by this paper
• Neurite growth from, and neuronal survival within, cultured explants of the nervous system: a critical review of morphometric and stereological methods, and suggestions for the future.

  1991cited by this paper
• Repeated stress-induced activation of corticotropin-releasing factor neurons enhances vasopressin stores and colocalization with corticotropin-releasing factor in the median eminence of rats.

  1991cited by this paper
• Elevated urinary free cortisol in patients with dementia.

  1991cited by this paper
• Different regulation of adrenocorticotropin and cortisol secretion in young, mentally healthy elderly and patients with senile dementia of Alzheimer's type.

  1991cited by this paper
• The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method.

  1991cited by this paper
• HPA axis responsivity to dexamethasone and cognitive impairment in dementia.

  1990cited by this paper
• The supraoptic and paraventricular nuclei of the human hypothalamus in relation to sex, age and Alzheimer's disease.

  1990cited by this paper
• Sources of error in the estimation of Leydig cell numbers in control and atrophied mammalian testes

  1990cited by this paper
• Cerebrospinal fluid corticotropin‐releasing factor levels and stimulation test in dementia of the alzheimer type

  1990cited by this paper
• Unbiased stereological estimation of the number of neurons in the human hippocampus

  1990cited by this paper
• Evidence for hippocampal regulation of neuroendocrine neurons of the hypothalamo-pituitary-adrenocortical axis

  1989cited by this paper
• Corticotropin-releasing factor immunoreactive neurons persist throughout the brain in Alzheimer's disease.

  1989cited by this paper
• Neuronal and synaptic measurements in the visual cortex of adult rats after undernutrition during normal or artificial rearing

  1989cited by this paper
• Characterization and biological activity of a rat monoclonal antibody to rat/human corticotropin-releasing factor.

  1989cited by this paper
• Corticotropin-releasing hormone in the human hypothalamus. Free-floating immunostaining method.

  1989cited by this paper
• The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis

  1988cited by this paper
• Total number of neurons and glial cells in human brain nuclei estimated by the disector and the fractionator

  1988cited by this paper
• Immunohistochemical study of neurons containing corticotropin‐releasing factor in Alzheimer's disease

  1987cited by this paper
• Influence of age and relative weight on cortisol suppression in normal subjects.

  1987cited by this paper
• The combined effects of unilateral enucleation and rearing in a “dim” red light on synapse‐to‐neuron ratios in the rat superior colliculus

  1987cited by this paper
• The efficiency of systematic sampling in stereology and its prediction *

  1987cited by this paper
• Comments on review by Coleman and Flood, 'Neuron Numbers and Dendritic Extent in Normal Aging and Alzheimer's Disease.' Density measures: parameters to avoid.

  1987cited by this paper
• Morphometry of size/volume variables and comparison of their bivariate relations in the nervous system under different conditions.

  1986cited by this paper
• The impact of recent stereological advances on quantitative studies of the nervous system.

  1986cited by this paper
• The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis.

  1986cited by this paper
• Regulation of multiple peptides in CRF parvocellular neurosecretory neurons: implications for the stress response.

  1986cited by this paper
• Stereology of arbitrary particles *

  1986cited by this paper
• An empirical assessment of stereological formulae applied to the counting of synaptic disks in the cerebral cortex

  1985cited by this paper
• Theories of biological aging.

  1985cited by this paper
• The unbiased estimation of number and sizes of arbitrary particles using the disector

  1984cited by this paper
• Corticotropin-releasing factor-immunoreactive neurons of the paraventricular nucleus become vasopressin positive after adrenalectomy.

  1984cited by this paper
• Stereological methods. Vol. 1: Practical methods for biological morphometry By . Academic Press, New York/London, 1979. xvi + 415 pp., $57.50

  1984cited by this paper
• Clinical diagnosis of Alzheimer's disease

  1984cited by this paper
• Chemical and biological characterization of corticotropin releasing factor.

  1983cited by this paper
• Immunocytochemical localization of corticotropin-releasing factor-like immunoreactivity in the human hypothalamus.

  1983cited by this paper
• Interaction of corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin secretion in vivo.

  1983cited by this paper
• Penetration of immunoreagents in Vibratome-sectioned brain: a light and electron microscopic study.

  1983cited by this paper
• Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin.

  1982cited by this paper
• Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin

  1982cited by this paper
• Immunocytochemical localization of corticotropin-releasing factor (CRF) in the rat brain.

  1982cited by this paper
• Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin

  1981cited by this paper
• Particle size‐shape distributions: the general spheroid problem: II. Stochastic model and practical guide

  1978cited by this paper
• Estimation of nuclear population from microtome sections

  1946cited by this paper
• A Syndrome produced by Diverse Nocuous Agents

  1936cited by this paper

• Corticotropin‐releasing factor signaling and its potential role in the prefrontal cortex‐dependent regulation of anxiety

  2023cites this paper
• Translational Strategies for Developing Biomarkers for Major Depression: Lessons Learned from Animal Models

  2022cites this paper
• The stress-axis in multiple sclerosis: Clinical, cellular, and molecular aspects.

  2021cites this paper
• A Systematic Review of the Association Between Psychological Stress and Dementia Risk in Humans

  2020cites this paper
• Corticotropin releasing factor-binding protein (CRF-BP) as a potential new therapeutic target in Alzheimer’s disease and stress disorders

  2019cites this paper
• Stress induced neural reorganization: A conceptual framework linking depression and Alzheimer's disease

  2017cites this paper
• Acute central effects of corticotropin-releasing factor (CRF) on energy balance: Effects of age and gender.

  2016cites this paper
• In Obesity, HPA Axis Activity Does Not Increase with BMI, but Declines with Aging: A Meta-Analysis of Clinical Studies

  2016cites this paper
• Delayed post-treatment with bone marrow-derived mesenchymal stem cells is neurorestorative of striatal medium-spiny projection neurons and improves motor function after neonatal rat hypoxia-ischemia.

  2015cites this paper
• Adding fuel to the fire: the impact of stress on the ageing brain.

  2015cites this paper
• Disruption of fetal hormonal programming (prenatal stress) implicates shared risk for sex differences in depression and cardiovascular disease.

  2014cites this paper
• The percentage of interneurons in the dorsal striatum of the rat, cat, monkey and human: A critique of the evidence

  2013cites this paper
• Altered Hypothalamic-Pituitary-Adrenal Axis Activity in Patients with Chronic Heart Failure

  2013cites this paper
• Sex Differences in HPA and HPG Axes Dysregulation in Major Depressive Disorder: The Role of Shared Brain Circuitry Between Hormones and Mood

  2013cites this paper
• Multiple Origins of Sex Differences in Brain

  2013cites this paper
• Neuron numbers in the hypothalamus of the normal aging rhesus monkey: Stability across the adult lifespan and between the sexes

  2012cites this paper
• Aging-Related Changes in Cutaneous Corticotropin-Releasing Hormone System Reflect a Defective Neuroendocrine-Stress Response in Aging

  2012cites this paper
• (Re-)activation of neurons in aging and dementia: lessons from the hypothalamus.

  2011cites this paper
• Expression patterns of corticotropin‐releasing factor, arginine vasopressin, histidine decarboxylase, melanin‐concentrating hormone, and orexin genes in the human hypothalamus

  2010cites this paper
• Cell numbers in the dorsal and median raphe nuclei of AS andAS/AGU rats

  2010cites this paper
• Altered Hypothalamic-Pituitary-Adrenal Axis Activity in Patients with Chronic Heart Failure

  2009cites this paper
• Aging and Alzheimer's Disease

  2009cites this paper
• The stress system in depression and neurodegeneration: focus on the human hypothalamus.

  2008cites this paper
• The human circadian timing system in aging, alzheimer's disease and depression

  2007cites this paper
• Gender Difference in Age-Related Number of Corticotropin-Releasing Hormone-Expressing Neurons in the Human Hypothalamic Paraventricular Nucleus and the Role of Sex Hormones

  2007cites this paper
• Relation between Corticotropin-Releasing Hormone Neuron Number in the Hypothalamic Paraventricular Nucleus and Depressive State in Alzheimer’s Disease

  2007cites this paper
• Hormonal influences on brain ageing quality: Focus on corticotropin releasing hormone-, vasopressin- and oxytocin-immunoreactive neurones in the human brain

  2005cites this paper
• Physiologic Aspects of Aging: Impact on Cancer Management and Decision Making, Part II

  2005cites this paper
• The stress system in the human brain in depression and neurodegeneration.

  2005influential citation
• Neuroprotection of Ischemic Brain by Vascular Endothelial Growth Factor is Critically Dependent on Proper Dosage and May Be Compromised by Angiogenesis

  2004cites this paper
• 103 – Aging and Alzheimer's Disease

  2002cites this paper
• Sexual Diergism of Hypothalamo-Pituitary–Adrenal Cortical Responses to Low-Dose Physotigmine in Elderly vs. Young Women and Men

  2002cites this paper
• Paraventricular nucleus of the human hypothalamus in primary hypertension: Activation of corticotropin‐releasing hormone neurons

  2002cites this paper
• About assumptions in estimation of density of neurons and glial cells.

  2002cites this paper
• Basal Hypothalamo-Pituitary-Adrenal Axis Activity and Corticotropin Feedback in Young and Older Men: Relationships to Magnetic Resonance Imaging-Derived Hippocampus and Cingulate Gyrus Volumes

  2002cites this paper
• Impact of aging on stress-responsive neuroendocrine systems.

  2001cites this paper
• Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in depression.

  2001influential citation
• [Neuroendocrine aging].

  2001cites this paper
• Corticotropin-releasing hormone protects neurons against insults relevant to the pathogenesis of Alzheimer's disease.

  2001cites this paper
• Organization of the human paraventricular hypothalamic nucleus

  2000cites this paper
• Neuropeptides and the Hypothalamic-Pituitary-Adrenocortical (HPA) System: Review of Recent Research Strategies in Depression

  2000cites this paper
• Endogenous vasopressin contributes to hypothalamic-pituitary-adrenocortical alterations in aged rats.

  2000cites this paper
• Physiologic and neuroendocrine responses to intravenous naloxone in subjects with Alzheimer's disease and age-matched controls.

  1999cites this paper
• Corticotropin-releasing factor – immunolabeled fibers in brain regions with localized kainate neurotoxicity

  1999cites this paper
• Age and species-dependent differences in the neurokinin B system in rat and human brain.

  1999cites this paper
• Activation and degeneration during aging: A morphometric study of the human hypothalamus

  1999cites this paper
• Cross-sensitization between immune and non-immune stressors. A role in the etiology of depression?

  1999cites this paper
• Depression in Parkinson's disease is not accompanied by more corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus.

  1998cites this paper
• Magnesium status and ageing: an update.

  1998cites this paper
• Cerebrospinal fluid prostaglandins and corticotropin releasing factor in schizophrenics and controls: relationship to sleep architecture.

  1998cites this paper
• Characterization of [125I]sauvagine binding to CRH2 receptors: membrane homogenate and autoradiographic studies.

  1998cites this paper
• Do aluminium and/or glutamate induce Alz-50 reactivity? A light microscopic immunohistochemical study

  1998cites this paper
• The human hypothalamo-neurohypophysial system in health and disease.

  1998cites this paper
• Arcuate nucleus of the hypothalamus: Effects of age and sex

  1998cites this paper
• Evidence for a postnatal doubling of neuron number in the developing human cerebral cortex between 15 months and 6 years.

  1998cites this paper
• Chapter II Neurobiology and neuropathology of the human hypothalamus

  1997cites this paper
• Reduced inferior olivary neuron number in early Down syndrome.

  1997cites this paper
• Estimation of the numerical densities of neurons and synapses in cerebral cortex.

  1997cites this paper
• Chapter 8 Neuroendocrine Aspects of the Aging Brain

  1997cites this paper
• Glucocorticoid hormone, aging brain and dementia.

  1997cites this paper
• Hyperactivity of the hypothalamic-pituitary-adrenal axis in aging: a gerogenetic or an adaptive factor?

  1997cites this paper
• Corticotropin‐Releasing Factor (CRF), CRF‐Binding Protein (CRF‐BP), and CRF/CRF‐BP Complex in Alzheimer's Disease and Control Postmortem Human Brain

  1997cites this paper
• The ‘glucocorticoid cascade’ hypothesis in man

  1997cites this paper
• Age-related changes of VIP, NPY and somatostatin-immunoreactive neurons in the cerebral cortex of aged rats.

  1997cites this paper
• With aging in humans the activity of the hypothalamus-pituitary-adrenal system increases and its diurnal amplitude flattens.

  1997cites this paper
• Section Review: Central & Peripheral Nervous Systems: Corticotropin releasing factor and Alzheimer's disease: recent developments with implications for more effective therapies

  1996cites this paper
• Total number of neurons in the neostriatal, pallidal, subthalamic, and substantia nigral nuclei of the rat basal ganglia: A stereological study using the cavalieri and optical disector methods

  1996cites this paper
• Enhanced adrenal sensitivity to adrenocorticotrophic hormone (ACTH) is evidence of HPA axis hyperactivity in Alzheimer's disease

  1996cites this paper
• Neuropeptides in hypothalamic pathology

  1996cites this paper
• Differential vasopressin and oxytocin innervation of the human parabrachial nucleus: no changes in Alzheimer's disease.

  1996cites this paper
• Comparison of the Number of Vasopressin‐Producing Hypothalamic Neurons in Rats and Humans

  1995cites this paper
• No vasopressin cell loss in the human hypothalamus in aging and Alzheimer's disease.

  1995cites this paper
• Alteration of corticotropin‐releasing factor immunoreactivity in MPTP‐treated rats

  1995cites this paper
• Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression.

  1995cites this paper
• Embedding, sectioning, immunocytochemical and stereological methods that optimise research on the lesioned adult rat spinal cord.

  1995cites this paper
• Development of the human hypothalamus

  1995cites this paper
• Ageing of the human hypothalamus.

  1995cites this paper
• Increased number of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of patients with multiple sclerosis.

  1995cites this paper
• Postnatal neurogenesis of the hypothalamic paraventricular and supraoptic nuclei in the Brazilian opossum brain.

  1995cites this paper
• Hypothalamic-pituitary-adrenal system function in patients with Alzheimer's disease.

  1995cites this paper
• Hippocampal markers of age-related memory dysfunction: behavioral, electrophysiological and morphological perspectives.

  1995cites this paper
• Increased Cortisol Levels in Aging and Alzheimer's Disease in Postmortem Cerebrospinal Fluid

  1994cites this paper
• Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients.

  1994cites this paper
• Similar Age Related Increase of Vasopressin Colocalization in Paraventricular Corticotropin‐Releasing Hormone Neurons in Controls and Alzheimer Patients

  1994cites this paper
• Are you using neuronal densities, synaptic densities or neurochemical densities as your definitive data? There is a better way to go.

  1994cites this paper