Disruption of neuromedin B receptor gene results in dysregulation of the pituitary-thyroid axis.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Molecular Endocrinology

• Publication date

  2006-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1677/JME.1.01892PMID 16461928
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Feedback regulation of thyrotropin-releasing hormone (TRH): mechanisms for the non-thyroidal illness syndrome.

  2004cited by this paper
• Stress-induced impairment of inhibitory avoidance learning in female neuromedin B receptor-deficient mice.

  2003cited by this paper
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  2003influential reference
• The Autocrine/Paracrine Regulation of Thyrotropin Secretion

  2003cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  1999influential reference
• Dangerous dogmas in medicine: the nonthyroidal illness syndrome.

  1999cited by this paper
• Studies of the Hormonal Regulation of Type 2 5'-Iodothyronine Deiodinase Messenger Ribonucleic Acid in Pituitary Tumor Cells Using Semiquantitative Reverse Transcription-Polymerase Chain Reaction* * This work was supported by NIH Grant DK-36256.

  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• Thyroid hormones rapidly and stringently regulate the messenger RNA levels of the thyrotropin-releasing hormone (TRH) receptor and the TRH-degrading ectoenzyme.

  1995influential reference
• Expression of the genes encoding bombesin-related peptides and their receptors in anterior pituitary tissue.

  1993cited by this paper
• Comparison of gene expression for two distinct bombesin receptor subtypes in postnatal rat central nervous system.

  1992cited by this paper
• Evidence for neuromedin-B synthesis in the rat anterior pituitary gland.

  1992influential reference
• Activation of neuromedin B-preferring bombesin receptors on rat glioblastoma C-6 cells increases cellular Ca2+ and phosphoinositides.

  1992cited by this paper
• Role of neuromedin B in control of the release of thyrotropin in hypothyroid and hyperthyroid rats.

  1992cited by this paper
• Molecular cloning of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells.

  1991cited by this paper
• cDNA cloning, characterization, and brain region-specific expression of a neuromedin-B-preferring bombesin receptor.

  1991influential reference
• Neuromedin B receptor in esophagus: evidence for subtypes of bombesin receptors.

  1989cited by this paper
• Role of neuromedin B in the control of the release of thyrotropin in the rat.

  1989influential reference
• INHIBITORY EFFECT OF NEUROMEDIN B ON THE RELEASE OF THYROTROPIN FROM PERIFUSED RAT PITUITARIES

  1989cited by this paper
• Localization of 7B2, neuromedin B, and neuromedin U in specific cell types of rat, mouse, and human pituitary, in rat hypothalamus, and in 30 human pituitary and extrapituitary tumors.

  1988influential reference
• Effect of bombesin on basal and stimulated secretion of some pituitary hormones in humans.

  1986cited by this paper
• Excess of beta-subunit of thyrotropin (TSH) in patients with idiopathic central hypothyroidism due to the secretion of TSH with reduced biological activity.

  1983cited by this paper
• Neuromedin B: a novel bombesin-like peptide identified in porcine spinal cord.

  1983cited by this paper
• THE PREPARATION OF I-131-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY.

  1963cited by this paper
• Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

  1962cited by this paper

• Bombesin receptors in GtoPdb v.2025.3

  2025cites this paper
• Neuromedin B receptor as a potential therapeutic target for corticotroph adenomas

  2023cites this paper
• Disruption of neuromedin B receptor improves mitochondrial oxidative phosphorylation capacity in gastrocnemius muscle of female mice.

  2022cites this paper
• Bombesin receptors in GtoPdb v.2021.2

  2021cites this paper
• Neuromedin B

  2021cites this paper
• Neuromedin B receptor disruption impairs adipogenesis in mice and 3T3-L1 cells.

  2019cites this paper
• Bombesin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

  2019cites this paper
• Pituitary Transcriptomic Study Reveals the Differential Regulation of lncRNAs and mRNAs Related to Prolificacy in Different FecB Genotyping Sheep

  2019cites this paper
• Characterization of NMB, GRP and their receptors (BRS3, NMBR and GRPR) in chickens.

  2017cites this paper
• Neuromedin: An insight into its types, receptors and therapeutic opportunities

  2017cites this paper
• Gene expression of T3‐regulated genes in a mouse model of the human thyroid hormone resistance

  2017cites this paper
• Chapter 6 – Thyroid-Stimulating Hormone

  2017cites this paper
• Neuromedin B and Its Receptor: Gene Cloning, Tissue Distribution and Expression Levels of the Reproductive Axis in Pigs

  2016cites this paper
• Mice with Deletion of Neuromedin B Receptor Exhibit Decreased Oral Glucose-Stimulated Insulin Release

  2016cites this paper
• Hypothalamus-Pituitary-Thyroid Axis.

  2016cites this paper
• Subchapter 22B – Neuromedin B

  2016cites this paper
• Insights into bombesin receptors and ligands: Highlighting recent advances.

  2015cites this paper
• The Impact of a Non-Functional Thyroid Receptor Beta upon Triiodotironine-Induced Cardiac Hypertrophy in Mice

  2015cites this paper
• Expression and regulation of neuromedin B in pituitary corticotrophs of male melanocortin 2 receptor-deficient mice.

  2014cites this paper
• Hypothalamic-pituitary thyroid axis alterations in female mice with deletion of the neuromedin B receptor gene.

  2014cites this paper
• High levels of circulating triiodothyronine induce plasma cell differentiation.

  2014cites this paper
• Thyroid hormone regulation of Sirtuin 1 expression and implications to integrated responses in fasted mice.

  2013cites this paper
• PPARα modulates the TSH β-subunit mRNA expression in thyrotrope TαT1 cells and in a mouse model.

  2013cites this paper
• The Sequence and Analysis Of An Inbred Pig Genome

  2013cites this paper
• The sequence and analysis of a Chinese pig genome

  2012cites this paper
• Thyroid hormone and estradiol have overlapping effects on kidney glutathione S-transferase-α gene expression.

  2012cites this paper
• Thyroid-stimulating Hormone

  2011cites this paper
• Liver glutathione S‐transferase α expression is decreased by 3,5,3′‐triiodothyronine in hypothyroid but not in euthyroid mice

  2011cites this paper
• harmacology and selectivity of various natural and synthetic bombesin related eptide agonists for human and rat bombesin receptors differs

  2011cites this paper
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  2010cites this paper
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  2009cites this paper
• Bombesin modulates the control of energy homeostasis and pituitary hormone release.

  2009cites this paper
• Glycosyltransferase Function in Core 2-Type Protein O Glycosylation

  2009influential citation
• International Union of Pharmacology. LXVIII. Mammalian Bombesin Receptors: Nomenclature, Distribution, Pharmacology, Signaling, and Functions in Normal and Disease States

  2008influential citation
• Mammalian Bombesin Receptors : Nomenclature , Distribution , Pharmacology , Signaling , and Functions in Normal and Disease States

  2008cites this paper
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  2008cites this paper
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  2008cites this paper
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  2007cites this paper
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  2007cites this paper
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