Effects of ketamine on vocal impairment, gait changes, and anhedonia induced by bilateral 6‐OHDA infusion into the substantia nigra pars compacta in rats: Therapeutic implications for Parkinson's disease

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Behavioural Brain Research

• Publication date

  2018-04-16

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.bbr.2017.12.041PMID 29307665
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Parkinson's disease].

  2022cited by this paper
• Situational Factors

  2020cited by this paper
• Emotional

  2020cited by this paper
• Effects of amphetamine on pro-social ultrasonic communication in juvenile rats: Implications for mania models.

  2017cited by this paper
• Re-emergent tremor in Parkinson's disease.

  2017cited by this paper
• Changes in neural circuitry associated with depression at pre-clinical, pre-motor and early motor phases of Parkinson's disease.

  2017cited by this paper
• Vocal training, levodopa, and environment effects on ultrasonic vocalizations in a rat neurotoxin model of Parkinson disease.

  2016cited by this paper
• Ketamine as a Prophylactic Against Stress-Induced Depressive-like Behavior.

  2016cited by this paper
• Long-term effect of sub-anesthetic ketamine in reducing L-DOPA-induced dyskinesias in a preclinical model.

  2016cited by this paper
• Epidemiology of Parkinson Disease.

  2016cited by this paper
• Evaluation of 50-kHz ultrasonic vocalizations in animal models of mania: Ketamine and lisdexamfetamine-induced hyperlocomotion in rats.

  2016cited by this paper
• Decreased approach behavior and nucleus accumbens immediate early gene expression in response to Parkinsonian ultrasonic vocalizations in rats

  2016cited by this paper
• The nonsteroidal antiinflammatory drug piroxicam reverses the onset of depressive-like behavior in 6-OHDA animal model of Parkinson's disease.

  2015cited by this paper
• Gait analysis in three different 6-hydroxydopamine rat models of Parkinson's disease.

  2015cited by this paper
• Involvement of Glutamate NMDA Receptors in the Acute, Long-Term, and Conditioned Effects of Amphetamine on Rat 50kHz Ultrasonic Vocalizations

  2015cited by this paper
• Non-motor signs in Parkinson's disease: a review.

  2015cited by this paper
• Non-motor signs in Parkinson's disease: a review.

  2015cited by this paper
• Environmental and Pharmacological Modulation of Amphetamine-Induced 50-kHz Ultrasonic Vocalizations in Rats

  2015cited by this paper
• Effects of Hypericum perforatum on turning behavior in an animal model of Parkinson's disease

  2015cited by this paper
• REM sleep deprivation promotes a dopaminergic influence in the striatal MT2 anxiolytic-like effects

  2015cited by this paper
• Changes in Rat 50-kHz Ultrasonic Vocalizations During Dopamine Denervation and Aging: Relevance to Neurodegeneration

  2015cited by this paper
• Relationships among rat ultrasonic vocalizations, behavioral measures of striatal dopamine loss, and striatal tyrosine hydroxylase immunoreactivity at acute and chronic time points following unilateral 6-hydroxydopamine-induced dopamine depletion.

  2015cited by this paper
• Amphetamine-induced appetitive 50-kHz calls in rats: a marker of affect in mania?

  2014cited by this paper
• Behavioral disorders in Parkinson's disease: the role of dopamine.

  2014cited by this paper
• Multiple factors are involved in the dysarthria associated with Parkinson's disease: a review with implications for clinical practice and research.

  2014influential reference
• A review of ketamine in affective disorders: current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action.

  2014cited by this paper
• Phencyclidine decreases tickling-induced 50-kHz ultrasound vocalizations in juvenile rats: a putative model of the negative symptoms of schizophrenia?

  2013cited by this paper
• Early Identification and Treatment of Communication and Swallowing Deficits in Parkinson Disease

  2013cited by this paper
• Biomarkers in Parkinson's disease (recent update).

  2013cited by this paper
• Understanding cognitive deficits in Parkinson's disease: lessons from preclinical animal models.

  2013cited by this paper
• Loss of dopaminergic nigrostriatal neurons accounts for the motivational and affective deficits in Parkinson’s disease

  2013cited by this paper
• Locomotion analysis and its applications in neurological disorders detection: state-of-art review

  2013cited by this paper
• Parkinson's disease patients show reduced cortical‐subcortical sensorimotor connectivity

  2013cited by this paper
• Affective communication in rodents: ultrasonic vocalizations as a tool for research on emotion and motivation

  2013cited by this paper
• Changes in behavior and ultrasonic vocalizations during antidepressant treatment in the maternally separated Wistar-Kyoto rat model of depression

  2013cited by this paper
• Studies of Depression-Related States in Animal Models of Parkinsonism

  2012influential reference
• Cognitive impairment in patients with Parkinson's disease: diagnosis, biomarkers, and treatment.

  2012cited by this paper
• Quantitative assessment of gait and neurochemical correlation in a classical murine model of Parkinson’s disease

  2012cited by this paper
• How does parkinsonism start? Prodromal parkinsonism motor changes in idiopathic REM sleep behaviour disorder.

  2012cited by this paper
• Basic parameters of articulatory movements and acoustics in individuals with Parkinson's disease

  2012cited by this paper
• Identifying prodromal Parkinson's disease: Pre‐Motor disorders in Parkinson's disease

  2012cited by this paper
• Ketamine for depression: where do we go from here?

  2012cited by this paper
• Motor and non-motor features of Parkinson's disease - a review of clinical and experimental studies.

  2012cited by this paper
• Testing social acoustic memory in rats: effects of stimulus configuration and long-term memory on the induction of social approach behavior by appetitive 50-kHz ultrasonic vocalizations.

  2012cited by this paper
• Mild dopaminergic lesions are accompanied by robust changes in subthalamic nucleus activity.

  2012cited by this paper
• The role of dopaminergic transmission through D1-like and D2-like receptors in amphetamine-induced rat ultrasonic vocalizations

  2012cited by this paper
• Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents.

  2012cited by this paper
• Tongue force and timing deficits in a rat model of Parkinson disease.

  2011cited by this paper
• Reproducibility and validity of patient-rated assessment of speech, swallowing, and saliva control in Parkinson's disease.

  2011cited by this paper
• The motor phenotype of Parkinson's disease in relation to age at onset

  2011cited by this paper
• utomated gait analysis in bilateral Parkinsonian rats and the role of l-DOPA herapy

  2011cited by this paper
• Depression in Parkinson disease—epidemiology, mechanisms and management

  2011cited by this paper
• Neonatal exposure to constant light prevents anhedonia-like behavior induced by constant light exposure in adulthood.

  2011cited by this paper
• Effects of D-cycloserine on MPTP-induced behavioral and neurological changes: potential for treatment of Parkinson's disease dementia.

  2011cited by this paper
• Subglottal pressure, tracheal airflow, and intrinsic laryngeal muscle activity during rat ultrasound vocalization.

  2011cited by this paper
• The prevalence and patterns of pharyngoesophageal dysmotility in patients with early stage Parkinson's disease

  2010cited by this paper
• Laryngeal somatosensory deficits in Parkinson’s disease: implications for speech respiratory and phonatory control

  2010cited by this paper
• Preserved serotonin transporter binding in de novo Parkinson’s disease: negative correlation with the dopamine transporter

  2010cited by this paper
• Automated quantitative gait analysis in animal models of movement disorders

  2010cited by this paper
• Quantitative evaluation of motor function before and after engraftment of dopaminergic neurons in a rat model of Parkinson's disease

  2010cited by this paper
• Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine.

  2010influential reference
• Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment.

  2009cited by this paper
• Perceptual characteristics of Parkinsonian speech: A comparison of the pharmacological effects of levodopa across speech and non-speech motor systems

  2009cited by this paper
• The relationship between quality of life and swallowing in Parkinson's disease

  2009cited by this paper
• Determination of 5-Hydroxytryptamine, Norepinephrine, Dopamine and Their Metabolites in Rat Brain Tissue by LC–ESI–MS–MS

  2009cited by this paper
• Parkinson's disease: The syndrome, the pathogenesis and pathophysiology

  2009cited by this paper
• Dopaminergic influence on rat tongue function and limb movement initiation

  2009influential reference
• Melatonin attenuates tyrosine hydroxylase loss and hypolocomotion in MPTP-lesioned rats.

  2008cited by this paper
• Limb use and complex ultrasonic vocalization in a rat model of Parkinson's disease: deficit-targeted training.

  2008cited by this paper
• Emotional, cognitive and neurochemical alterations in a premotor stage model of Parkinson's disease.

  2008cited by this paper
• Maternal care, isolation-induced infant ultrasonic calling, and their relations to adult anxiety-related behavior in the rat.

  2008cited by this paper
• Nonmotor symptoms in Parkinson's disease: Investigating early‐phase onset of behavioral dysfunction in the 6‐hydroxydopamine‐lesioned rat model

  2008cited by this paper
• The 6-Hydroxydopamine model of parkinson’s disease

  2007cited by this paper
• High frequency stimulation of the subthalamic nucleus improves speed of locomotion but impairs forelimb movement in Parkinsonian rats.

  2007cited by this paper
• Neuroprotective effect of ketamine/xylazine on two rat models of Parkinson's disease.

  2007cited by this paper
• Qualitative changes in ultrasonic vocalization in rats after unilateral dopamine depletion or haloperidol: a preliminary study.

  2007cited by this paper
• Tickling-induced 50-kHz ultrasonic vocalization is individually stable and predicts behaviour in tests of anxiety and depression in rats.

  2007cited by this paper
• Situational factors, conditions and individual variables which can determine ultrasonic vocalizations in male adult Wistar rats.

  2007cited by this paper
• Different parkinsonism models produce a time-dependent induction of COX-2 in the substantia nigra of rats.

  2006cited by this paper
• The neurobiology of positive emotions.

  2006cited by this paper
• The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

  2005cited by this paper
• Comparison of bilaterally 6-OHDA- and MPTP-lesioned rats as models of the early phase of Parkinson's disease: histological, neurochemical, motor and memory alterations.

  2005cited by this paper
• Principles of Rat Communication: Quantitative Parameters of Ultrasonic Calls in Rats

  2005cited by this paper
• NMDA receptor antagonists ameliorate the stepping deficits produced by unilateral medial forebrain bundle injections of 6-OHDA in rats

  2004cited by this paper
• Higher incidence of depression preceding the onset of Parkinson's disease: A register study

  2003cited by this paper
• The Lesion of the Rat Substantia Nigra pars compacta Dopaminergic Neurons as a Model for Parkinson's Disease Memory Disabilities

  2002cited by this paper
• Nucleus accumbens amphetamine microinjections unconditionally elicit 50-kHz ultrasonic vocalizations in rats.

  2001cited by this paper
• 50-kHz chirping (laughter?) in response to conditioned and unconditioned tickle-induced reward in rats: effects of social housing and genetic variables.

  2000cited by this paper
• [Epidemiology of Parkinson disease].

  1998cited by this paper
• Stimulation of basal and L-DOPA-induced motor activity by glutamate antagonists in animal models of Parkinson's disease.

  1997cited by this paper
• Unilateral 6-hydroxydopamine lesions of meso-striatal dopamine neurons and their physiological sequelae.

  1996cited by this paper
• Are NMDA antagonistic properties relevant for antiparkinsonianlike activity in rats?—Case of amantadine and memantine

  1994cited by this paper
• NMDA antagonists potentiate antiparkinsonian actions of L‐dopa in monoamine‐depleted rats

  1990cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper
• [Maternal care].

  1970cited by this paper
• [Determination of 5-hydroxytryptamine].

  1958influential reference
• Usage and Distribution for Commercial Purposes Requires Written Permission. Case Reports Showing a Long-term Effect of Subanesthetic Ketamine Infusion in Reducing L-dopa-induced Dyskinesias

  year unknowncited by this paper

• The Effect of Neurodegeneration on Ultrasonic Vocalisations (USV) and Their Neuronal Substrates in Mice and Rats: A Systematic Review

  2026cites this paper
• Challenges and Opportunities in Exploring Non‐Motor Symptoms in 6‐Hydroxydopamine Models of Parkinson's Disease: A Systematic Review

  2025cites this paper
• Ketamine, Esketamine, and Arketamine: Their Mechanisms of Action and Applications in the Treatment of Depression and Alleviation of Depressive Symptoms

  2024cites this paper
• Exploring the multifaceted potential of (R)-ketamine beyond antidepressant applications

  2024cites this paper
• Positron emission tomography neuroimaging of [18F]fluorodeoxyglucose uptake and related behavior in the Pink1−/− rat model of Parkinson disease

  2024cites this paper
• Investigating affective neuropsychiatric symptoms in rodent models of Parkinson's disease.

  2024cites this paper
• Exploring Parkinson’s Disease-Associated Depression: Role of Inflammation on the Noradrenergic and Serotonergic Pathways

  2024cites this paper
• Rats chirp with their mouth full: During an experimental meal, adult male Wistar rats emitted flat ultrasonic vocalisations upon feeding

  2023cites this paper
• AutoRG: An automatized reach-to-grasp platform technology for assessing forelimb motor function, neural circuit activation, and cognition in rodents

  2023cites this paper
• Mood disturbances in Parkinson's disease: From prodromal origins to application of animal models.

  2023cites this paper
• A novel curcumin oil solution can better alleviate the motor activity defects and neuropathological damage of a Parkinson’s disease mouse model

  2022cites this paper
• The effect of ketamine on anhedonia: improvements in dimensions of anticipatory, consummatory, and motivation-related reward deficits

  2022cites this paper
• Application of Neurotoxin-Induced Animal Models in the Study of Parkinson’s Disease-Related Depression: Profile and Proposal

  2022cites this paper
• Therapeutic Approaches to Non-Motor Symptoms of Parkinson's Disease: A Current Update on Preclinical Evidence

  2022cites this paper
• Neuropsychiatric and Cognitive Deficits in Parkinson’s Disease and Their Modeling in Rodents

  2021cites this paper
• The antimanic-like effects of andrographolide and quercetin

  2021cites this paper
• Long-term increase in sensitivity to ketamine's behavioral effects in mice exposed to mild blast induced traumatic brain injury.

  2021cites this paper
• Increased energy expenditure and activated β3‐AR‐cAMP‐PKA signaling pathway in the interscapular brown adipose tissue of 6‐OHDA‐induced Parkinson's disease model rats

  2020cites this paper
• Modelling cognitive deficits in Parkinson's disease: Is CA2 a gateway for hippocampal synucleinopathy?

  2020cites this paper
• Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease.

  2020cites this paper
• Neuropsychiatric Disorders in Parkinson’s Disease: What Do We Know About the Role of Dopaminergic and Non-dopaminergic Systems?

  2020cites this paper
• Ketamine reversed short-term memory impairment and depressive-like behavior in animal model of Parkinson's disease.

  2020cites this paper
• Increased emissions of 50-kHz ultrasonic vocalizations in hemiparkinsonian rats repeatedly treated with dopaminomimetic drugs: A potential preclinical model for studying the affective properties of dopamine replacement therapy in Parkinson's disease.

  2020cites this paper
• The hidden side of Parkinson's disease: Studying pain, anxiety and depression in animal models

  2019cites this paper