Identification of Streptococcal M-Protein Cardiopathogenic Epitopes in Experimental Autoimmune Valvulitis

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of Cardiovascular Translational Research

• Publication date

  2014-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s12265-013-9526-4PMID 24346820PMCID PMC3943786
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Streptococcus and rheumatic fever

  2012cited by this paper
• Microbial Adhesion and Invasion

  2011cited by this paper
• An alternative technique for the induction of autoimmune valvulitis in a rat model of rheumatic heart disease.

  2010cited by this paper
• Priming the immune system for heart disease: a perspective on group A streptococci.

  2010cited by this paper
• Cardiovascular disease in patients with inflammatory rheumatic disease is associated with up-regulation of markers of inflammation in cardiac microvessels and cardiomyocytes.

  2010cited by this paper
• B- and T-Cell Responses in Group A Streptococcus M-Protein- or Peptide-Induced Experimental Carditis

  2009cited by this paper
• Coiled-Coil Irregularities and Instabilities in Group A Streptococcus M1 Are Required for Virulence

  2008cited by this paper
• Comprehensive analysis of antibody responses to streptococcal and tissue antigens in patients with acute rheumatic fever.

  2008cited by this paper
• Clinical Infectious Disease: Clinical Syndromes – Respiratory Tract

  2008cited by this paper
• Mimicry in Recognition of Cardiac Myosin Peptides by Heart-Intralesional T Cell Clones from Rheumatic Heart Disease1

  2006influential reference
• Molecular mimicry in the autoimmune pathogenesis of rheumatic heart disease

  2006cited by this paper
• T Cell Mimicry and Epitope Specificity of Cross-Reactive T Cell Clones from Rheumatic Heart Disease1

  2005cited by this paper
• Temporal association of the appearance of mucoid strains of Streptococcus pyogenes with a continuing high incidence of rheumatic fever in Utah.

  2004cited by this paper
• Heart infiltrating T cell clones from a rheumatic heart disease patient display a common TCR usage and a degenerate antigen recognition pattern.

  2004cited by this paper
• T cell mimicry in inflammatory heart disease.

  2004cited by this paper
• Rheumatic Heart Disease Proinflammatory Cytokines Play a Role in the Progression and Maintenance of Valvular Lesions

  2004cited by this paper
• Rheumatic heart disease: proinflammatory cytokines play a role in the progression and maintenance of valvular lesions.

  2004cited by this paper
• Autoimmunity and molecular mimicry in the pathogenesis of post-streptococcal heart disease.

  2003cited by this paper
• Induction of autoimmune valvulitis in Lewis rats following immunization with peptides from the conserved region of group A streptococcal M protein.

  2003cited by this paper
• Induction of myocarditis and valvulitis in lewis rats by different epitopes of cardiac myosin and its implications in rheumatic carditis.

  2002influential reference
• Acute pharyngitis.

  2001cited by this paper
• Induction of Autoimmune Valvular Heart Disease by Recombinant Streptococcal M Protein

  2001influential reference
• T-Cell Reactivity against Streptococcal Antigens in the Periphery Mirrors Reactivity of Heart-Infiltrating T Lymphocytes in Rheumatic Heart Disease Patients

  2001cited by this paper
• Rheumatic fever in the 21st century.

  2001cited by this paper
• Pathogenic mechanisms in rheumatic carditis: focus on valvular endothelium.

  2001cited by this paper
• Effects of Microbes on the Immune System

  2000cited by this paper
• Molecular analysis of polyreactive monoclonal antibodies from rheumatic carditis: human anti-N-acetylglucosamine/anti-myosin antibody V region genes.

  1998cited by this paper
• Ethnic differences in expression of susceptibility marker(s) in rheumatic fever/rheumatic heart disease patients.

  1998cited by this paper
• Molecular analysis of human cardiac myosin-cross-reactive B- and T-cell epitopes of the group A streptococcal M5 protein

  1997cited by this paper
• Rheumatic Aschoff nodules revisited. II: Cytokine expression corroborates recently proposed sequential stages

  1997cited by this paper
• Rheumatic fever.

  1997cited by this paper
• Streptococcal M protein peptide with similarity to myosin induces CD4+ T cell-dependent myocarditis in MRL/++ mice and induces partial tolerance against coxsakieviral myocarditis.

  1996cited by this paper
• Autoantibody germ-line gene segment encodes VH and VL regions of a human anti-streptococcal monoclonal antibody recognizing streptococcal M protein and human cardiac myosin epitopes.

  1995cited by this paper
• Human heart-infiltrating T-cell clones from rheumatic heart disease patients recognize both streptococcal and cardiac proteins.

  1995cited by this paper
• Persistence of acute rheumatic fever in the intermountain area of the United States.

  1994cited by this paper
• Guidelines for the diagnosis of rheumatic fever. Jones Criteria, 1992 update. Special Writing Group of the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association.

  1992cited by this paper
• Group A Streptococci: Molecular Mimicry, Autoimmunity and Infection

  1992cited by this paper
• Streptococcal M protein: molecular design and biological behavior

  1989cited by this paper
• Identification of mononuclear cells and T cell subsets in rheumatic valvulitis.

  1989cited by this paper
• Group A streptococcal serotypes isolated from patients and sibling contacts during the resurgence of rheumatic fever in the United States in the mid-1980s.

  1989cited by this paper
• Resurgence of acute rheumatic fever in the intermountain area of the United States.

  1987cited by this paper
• Protective and heart-cross-reactive epitopes of type 19 streptococcal M protein.

  1987cited by this paper
• Myosin: a link between streptococci and heart.

  1985cited by this paper
• Presence of two distinct regions in the coiled-coil structure of the streptococcal Pep M5 protein: relationship to mammalian coiled-coil proteins and implications to its biological properties.

  1985cited by this paper
• Tissue distribution of lymphocytes in rheumatic heart valves as defined by monoclonal anti-T cell antibodies.

  1983cited by this paper
• Streptococcal rheumatic carditis

  1983cited by this paper
• Tropomyosin-like seven residue periodicity in three immunologically distinct streptococal M proteins and its implications for the antiphagocytic property of the molecule

  1980cited by this paper
• Streptococcal diseases and the immune response

  1980cited by this paper
• Principles and practice of infectious diseases. Vols 1 and 2.

  1979cited by this paper
• Heart-reactive antibody associated with rheumatic fever: characterization and diagnostic significance.

  1970cited by this paper
• Streptococci and rheumatic fever.

  1967cited by this paper

• Mechanisms of mitral valve development and disease.

  2026cites this paper
• Potential Involvement of M1 Macrophage and VLA4/VCAM-1 Pathway in the Valvular Damage Due to Rheumatic Heart Disease.

  2024cites this paper
• IgG2 rules: N-acetyl-β-D-glucosamine-specific IgG2 and Th17/Th1 cooperation may promote the pathogenesis of acute rheumatic heart disease and be a biomarker of the autoimmune sequelae of Streptococcus pyogenes

  2023cites this paper
• The Role of Inflammation and Oxidative Stress in Rheumatic Heart Disease

  2022cites this paper
• Characterization of an experimental model to determine streptococcal M protein–induced autoimmune cardiac and neurobehavioral abnormalities

  2022cites this paper
• Requirements for a Robust Animal Model to Investigate the Disease Mechanism of Autoimmune Complications Associated With ARF/RHD

  2021cites this paper
• Rheumatic Heart Valve Disease Pathophysiology and Underlying Mechanisms

  2021cites this paper
• Preclinical safety and immunogenicity of Streptococcus pyogenes (Strep A) peptide vaccines

  2021cites this paper
• Pathogenesis of Acute Rheumatic Fever

  2021cites this paper
• Preclinical safety and immunogenicity of Streptococcus pyogenes (Strep A) peptide vaccines

  2021cites this paper
• Predictors of rheumatic fever in sore throat patients: a systematic review and meta-analysis

  2021cites this paper
• Group A streptococcal antigen exposed rat model to investigate neurobehavioral and cardiac complications associated with post‐streptococcal autoimmune sequelae

  2021cites this paper
• In Search of the Holy Grail: A Specific Diagnostic Test for Rheumatic Fever

  2021cites this paper
• Rheumatic heart disease: A review of the current status of global research activity.

  2020cites this paper
• Group A streptococcal M-protein specific antibodies and T-cells drive the pathology observed in the rat autoimmune valvulitis model

  2019influential citation
• The Limitations of the Rheumatogenic Concept for Group A Streptococcus: Systematic Review and Genetic Analysis.

  2019cites this paper
• Molecular Mimicry, Autoimmunity, and Infection: The Cross-Reactive Antigens of Group A Streptococci and their Sequelae

  2019influential citation
• Dysregulated IL-1&bgr;-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by Hydroxychloroquine

  2018cites this paper
• Streptococcal pharyngitis and rheumatic heart disease: the superantigen hypothesis revisited.

  2018cites this paper
• Group G Streptococcus Induces an Autoimmune Carditis Mediated by Interleukin 17A and Interferon &ggr; in the Lewis Rat Model of Rheumatic Heart Disease

  2018cites this paper
• Pathogens and autoimmune hepatitis

  2018cites this paper
• Contribution of cryptic epitopes in designing a group A streptococcal vaccine

  2018cites this paper
• T cell subsets: an integral component in pathogenesis of rheumatic heart disease

  2017cites this paper
• A Critical Role of Zinc Importer AdcABC in Group A Streptococcus-Host Interactions During Infection and Its Implications for Vaccine Development

  2017cites this paper
• Genome-wide analysis of genetic risk factors for rheumatic heart disease in Aboriginal Australians provides support for pathogenic molecular mimicry

  2017cites this paper
• Post-Streptococcal Autoimmune Sequelae: Rheumatic Fever and Beyond

  2016cites this paper
• Repeat exposure to group A streptococcal M protein exacerbates cardiac damage in a rat model of rheumatic heart disease

  2016cites this paper
• An immunological perspective on rheumatic heart disease pathogenesis: more questions than answers

  2016cites this paper
• Post-infectious group A streptococcal autoimmune syndromes and the heart.

  2015cites this paper
• Panax Notoginseng Saponins Ameliorates Coxsackievirus B3-Induced Myocarditis by Activating the Cystathionine-γ-Lyase/Hydrogen Sulfide Pathway

  2015cites this paper
• Acute rheumatic fever and rheumatic heart disease

  2015cites this paper
• Review and Updates in Regenerative and Personalized Medicine, Preclinical Animal Models, and Clinical Care in Cardiovascular Medicine

  2015cites this paper
• Animal Models to Investigate the Pathogenesis of Rheumatic Heart Disease

  2014cites this paper
• Rheumatic Fever, Autoimmunity, and Molecular Mimicry: The Streptococcal Connection

  2014influential citation