New insights into the pathophysiological role for cytokines in heart failure.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Cardiovascular Research

• Publication date

  1999-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0008-6363(99)00050-4PMID 10533591
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The effect of renin–angiotensin system inhibitors on pro‐ and anti‐inflammatory cytokine production

  1998cited by this paper
• Cardiac endothelin-1 plays a critical role in the functional deterioration of left ventricles during the transition from compensatory hypertrophy to congestive heart failure in salt-sensitive hypertensive rats.

  1998cited by this paper
• Effects of Tumor Necrosis Factor Gene Polymorphisms on Patients With Congestive Heart Failure

  1998cited by this paper
• Prevention of ventricular remodeling.

  1998cited by this paper
• Cytokine Gene Expression After Myocardial Infarction in Rat Hearts

  1998cited by this paper
• Denopamine, a β1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-α production in the heart

  1998cited by this paper
• Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats.

  1998cited by this paper
• Elevated circulating levels of C-C chemokines in patients with congestive heart failure.

  1998cited by this paper
• Oscillatory shear stress stimulates adhesion molecule expression in cultured human endothelium.

  1998cited by this paper
• Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha.

  1998cited by this paper
• Interleukin-1 in myocardium and coronary arteries of patients with dilated cardiomyopathy.

  1998cited by this paper
• Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.

  1998cited by this paper
• Adenosine inhibits lipopolysaccharide-induced cardiac expression of tumor necrosis factor-alpha.

  1998cited by this paper
• Randomised investigation of effects of pentoxifylline on left-ventricular performance in idiopathic dilated cardiomyopathy.

  1998cited by this paper
• Cytokine gene expression after myocardial infarction in rat hearts: possible implication in left ventricular remodeling.

  1998cited by this paper
• Cyclic stretch upregulates production of interleukin-8 and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in human endothelial cells.

  1998cited by this paper
• Effects of tumor necrosis factor gene polymorphisms on patients with congestive heart failure. VEST Investigators for TNF Genotype Analysis. Vesnarinone Survival Trial.

  1998cited by this paper
• Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart.

  1998cited by this paper
• Beneficial effects of amlodipine in a murine model of congestive heart failure induced by viral myocarditis. A possible mechanism through inhibition of nitric oxide production.

  1997cited by this paper
• Vesnarinone limits infarct size via adenosine-dependent mechanisms in the canine heart.

  1997cited by this paper
• Amiodarone inhibits production of tumor necrosis factor-alpha by human mononuclear cells: a possible mechanism for its effect in heart failure.

  1997cited by this paper
• Modulation of cytokine production and protection against lethal endotoxemia by the cardiac glycoside ouabain.

  1997cited by this paper
• Plasma levels of the monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 are elevated in patients with acute myocardial infarction.

  1997cited by this paper
• Tumor Necrosis Factor-α Provokes a Hypertrophic Growth Response in Adult Cardiac Myocytes

  1997cited by this paper
• Role of cytokines in the mechanism of action of amlodipine: the PRAISE Heart Failure Trial. Prospective Randomized Amlodipine Survival Evaluation.

  1997cited by this paper
• The Role of Cytokines

  1997cited by this paper
• The effect of digoxin on mortality and morbidity in patients with heart failure.

  1997cited by this paper
• Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha.

  1997cited by this paper
• Tumor necrosis factor-alpha provokes a hypertrophic growth response in adult cardiac myocytes.

  1997cited by this paper
• Hemodynamic regulation of tumor necrosis factor-alpha gene and protein expression in adult feline myocardium.

  1997cited by this paper
• Circulating interleukin-6 in severe heart failure.

  1997cited by this paper
• Sphingosine Mediates the Immediate Negative Inotropic Effects of Tumor Necrosis Factor-α in the Adult Mammalian Cardiac Myocyte*

  1997cited by this paper
• Chronic hypoxia modulates the interleukin-1beta-stimulated inducible nitric oxide synthase pathway in cardiac myocytes.

  1997cited by this paper
• Increased expression of interleukin-1 beta and monocyte chemotactic and activating factor/monocyte chemoattractant protein-1 in the hypertrophied and failing heart with pressure overload.

  1997cited by this paper
• Dilated Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Tumor Necrosis Factor-α

  1997cited by this paper
• Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart.

  1996cited by this paper
• Interaction of cytotoxic T lymphocytes and guinea pig ventricular myocytes. Pharmacological modulation by blocking K+ currents in cytotoxic T lymphocytes.

  1996cited by this paper
• Vesnarinone: a potential cytokine inhibitor.

  1996cited by this paper
• Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group.

  1996cited by this paper
• Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart

  1996cited by this paper
• Persistent expression of cytokine in the chronic stage of viral myocarditis in mice.

  1996cited by this paper
• Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death.

  1996cited by this paper
• Effect of amiodarone on clinical status and left ventricular function in patients with congestive heart failure. CHF-STAT Investigators.

  1996cited by this paper
• Dilated cardiomyopathy associated with hepatitis C virus infection.

  1995cited by this paper
• Interleukin-1 beta induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture.

  1995cited by this paper
• Integrins and signal transduction pathways: the road taken.

  1995cited by this paper
• Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophy.

  1995cited by this paper
• Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes.

  1995cited by this paper
• Immune modulation of cardiac function: a new frontier.

  1995cited by this paper
• Inhibition of cytokine production by a new inotropic agent, vesnarinone, in human lymphocytes, T cell line, and monocytic cell line.

  1994cited by this paper
• Transition from compensatory hypertrophy to dilated, failing left ventricles in Dahl salt-sensitive rats.

  1994cited by this paper
• Phosphoramidon does not inhibit endogenous endothelin-1 release stimulated by hemorrhage, cytokines and hypoxia in rats.

  1994cited by this paper
• Cytokine and murine coxsackievirus B3 myocarditis. Interleukin-2 suppressed myocarditis in the acute stage but enhanced the condition in the subsequent stage.

  1994cited by this paper
• Increased circulating cytokines in patients with myocarditis and cardiomyopathy.

  1994cited by this paper
• Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro.

  1994cited by this paper
• Therapeutic Effect of Anti‐Tumor Necrosis Factor‐α Antibody on the Murine Model of Viral Myocarditis Induced by Encephalomyocarditis Virus

  1994cited by this paper
• Induction of Nitric Oxide Synthase Gene by Interleukin‐1β in Cultured Rat Cardiocytes

  1994cited by this paper
• Treatment of virus-induced myocardial injury with a novel immunomodulating agent, vesnarinone. Suppression of natural killer cell activity and tumor necrosis factor-alpha production.

  1994cited by this paper
• Effects of vesnarinone on morbidity and mortality in patients with heart failure. Vesnarinone Study Group.

  1993cited by this paper
• Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation

  1993cited by this paper
• Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart.

  1993cited by this paper
• How should physicians view heart failure? The philosophical and physiological evolution of three conceptual models of the disease.

  1993cited by this paper
• Effects of vesnarinone on morbidity and mortality in patients with heart failure

  1993cited by this paper
• Negative inotropic effects of cytokines on the heart mediated by nitric oxide.

  1992cited by this paper
• Mechanical forces and their second messengers in stimulating cell growth in vitro.

  1992cited by this paper
• Elevated circulating levels of tumor necrosis factor in severe chronic heart failure.

  1990cited by this paper
• Cytokines: coordinators of immune and inflammatory responses.

  1990cited by this paper
• Indirect inhibition of myocyte RNA and protein synthesis by interleukin-1.

  1990cited by this paper
• Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte beta-adrenergic responsiveness.

  1989cited by this paper
• Coxsackievirus B-3 myocarditis. Acute and chronic forms of the disease caused by different immunopathogenic mechanisms.

  1987cited by this paper

• Network analysis, sequence and structure dynamics of key proteins of coronavirus and human host, and molecular docking of selected phytochemicals of nine medicinal plants

  2020cites this paper
• Identifying panaxynol, a natural activator of nuclear factor erythroid-2 related factor 2 (Nrf2) from American ginseng as a suppressor of inflamed macrophage-induced cardiomyocyte hypertrophy.

  2015influential citation
• Malnutrition and Gut Flora Dysbiosis: Specific Therapies for Emerging Comorbidities in Heart Failure

  2015cites this paper
• Cardiopulmonary reflex, cardiac cytokines, and nandrolone decanoate: response to resistance training in rats.

  2015cites this paper
• Release kinetics of inflammatory biomarkers in a clinical model of acute myocardial infarction.

  2015cites this paper
• Coenzyme Q10 protects against acute consequences of experimental myocardial infarction in rats.

  2015cites this paper
• Coenzyme Q 10 protects against acute consequences of experimental myocardial infarction in rats

  2015cites this paper
• The plasma proteome and outcome in patients with heart failure

  2015cites this paper
• Neurohumoral improvement and torsional dynamics in patients with heart failure after treatment with levosimendan

  2014cites this paper
• Comparison of single-dose and repeated levosimendan infusion in patients with acute exacerbation of advanced heart failure

  2014cites this paper
• Das menschliche Herz als Schockorgan in der Anaphylaxie

  2014cites this paper
• Human heart as a shock organ in anaphylaxis

  2014cites this paper
• Influência da Suplementação de Dieta com Diferentes Doses de Vitamina D sobre Variáveis Cardíacas em Ratos

  2011cites this paper
• The Cytokines and Heart Failure - A Review

  2011cites this paper
• Levosimendan in the treatment of cardiogenic shock.

  2010cites this paper
• Downregulation of oxytocin receptors in right ventricle of rats with monocrotaline‐induced pulmonary hypertension

  2010cites this paper
• Human cardiac mast cells in anaphylaxis.

  2010cites this paper
• Tratamiento de la depresión miocárdica por sepsis con levosimendan. Serie de casos y revisión de la bibliografía

  2010cites this paper
• Anti-inflammatory effect of physical training in heart failure: role of TNF-alpha and IL-10.

  2009cites this paper
• Efeito anti-inflamatório do treinamento físico na insuficiência cardíaca: papel do TNF-α e da IL-10

  2009cites this paper
• Altered Interleukin-1 Receptor Antagonist and Interleukin-18 mRNA Expression in Myocardial Tissues of Patients with Dilatated Cardiomyopathy

  2008cites this paper
• Enhancer AVE9488 After Experimental Myocardial Infarction Improvement in Left Ventricular Remodeling by the Endothelial Nitric Oxide Synthase

  2008cites this paper
• Immune mechanisms in pediatric cardiovascular disease

  2008cites this paper
• Malnutrition and chronic heart failure

  2008cites this paper
• Invited review: Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms

  2008cites this paper
• Pathophysiological role and clinical relevance of cytokines in hypertensive heart failure. A combined clinical and experimental study

  2007cites this paper
• 2 CHAPTER 2 Immune mechanisms in pediatric cardiovascular disease

  2007cites this paper
• Alterações na produção de TNF-a e IL-10 no músculo esquelético de ratos com insuficiência cardíaca secundária a infarto do miocárdio: possível efeito antiinflamatório do treinamento aeróbio moderado.

  2007cites this paper
• The role of statins in heart failure

  2007cites this paper
• CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: impact of pre-inflammatory stimuli and renin-angiotensin system modulators.

  2007cites this paper
• Parallel gene expressions of IL-6 and BNP during cardiac hypertrophy complicated with diastolic dysfunction in spontaneously hypertensive rats.

  2007cites this paper
• A review of levosimendan in the treatment of heart failure

  2006cites this paper
• Analysis of circulating apoptosis mediators and proinflammatory cytokines in patients with idiopathic hypertrophic cardiomyopathy: comparison between nonobstructive and dilated-phase hypertrophic cardiomyopathy.

  2005cites this paper
• Analysis of post coronary bypass surgery risk factors and scoring system with study of immunogenetic epidemiology

  2005cites this paper
• Cardioprotection by Aldosterone Receptor Antagonism in Heart Failure: 1. The Role of Aldosterone in Heart Failure

  2005cites this paper
• Effect of Thalidomide on Cardiac Remodeling in Chronic Heart Failure: Results of a Double-Blind, Placebo-Controlled Study

  2005influential citation
• Etanercept or intravenous immunoglobulin attenuates expression of genes involved in post-myocardial infarction remodeling.

  2005influential citation
• Favourable clinical outcome in patients with cardiogenic shock due to fulminant myocarditis supported by percutaneous extracorporeal membrane oxygenation.

  2005cites this paper
• Levosimendan reduces plasma B-type natriuretic peptide and interleukin 6, and improves central hemodynamics in severe heart failure patients.

  2004cites this paper
• Effects of levosimendan on circulating pro-inflammatory cytokines and soluble apoptosis mediators in patients with decompensated advanced heart failure.

  2004cites this paper
• Gene expression profiling during the transition to failure in TNF-alpha over-expressing mice demonstrates the development of autoimmune myocarditis.

  2004cites this paper
• Níveis de citocinas proinflamatórias e seus antagonistas em pacientes com insuficiência aórtica crônica importante.

  2004cites this paper
• Sitokin, Nitrik Oksit ve Süperoksit Dismutaz Düzeylerinin Miyokard Fonksiyonu Üzerine Etkileri

  2004cites this paper
• Expression of inducible nitric oxide synthase is increased in patients with heart failure due to ischemic disease.

  2004cites this paper
• Eprosartan improves cardiac performance, reduces cardiac hypertrophy and mortality and downregulates myocardial monocyte chemoattractant protein-1 and inflammation in hypertensive heart disease

  2004cites this paper
• Effects of growth hormone on circulating cytokine network, and left ventricular contractile performance and geometry in patients with idiopathic dilated cardiomyopathy.

  2003cites this paper
• Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity.

  2003cites this paper
• Immunomodulatory Effects of Physical Training in Chronic Heart Failure

  2003cites this paper
• Role of chemokines in the pathogenesis of congestive heart failure

  2003cites this paper
• New aspects for the role of physical training in the management of patients with chronic heart failure.

  2003cites this paper
• Inflammation and Cardiac Diseases

  2003cites this paper
• Immunomodulation in Heart Failure: Experimental Models

  2003cites this paper
• Arrhythmogenic and inotropic effects of interferon investigated in perfused and in vivo rat hearts: influences of cardiac hypertrophy and isoproterenol.

  2002cites this paper
• Role of Myocardial Inducible Nitric Oxide Synthase in Contractile Dysfunction and &bgr;-Adrenergic Hyporesponsiveness in Rats With Experimental Volume-Overload Heart Failure

  2002cites this paper
• Physical training modulates proinflammatory cytokines and the soluble Fas/soluble Fas ligand system in patients with chronic heart failure.

  2002cites this paper
• Effects of captopril and omapatrilat on early post-myocardial infarction survival and cardiac hemodynamics in rats: interaction with cardiac cytokine expression.

  2002cites this paper
• CHF: circulatory homeostasis gone awry.

  2002cites this paper
• Coronary microembolization: the role of TNF-alpha in contractile dysfunction.

  2002cites this paper
• Cytokines and anti-cytokine therapeutic approaches to chronic heart failure.

  2002cites this paper
• Inotropic Agents and Immune Modulation

  2002cites this paper
• The enhanced plasma levels of soluble tumor necrosis factor receptors (sTNF-R1; sTNF-R2) and interleukin-10 (IL-10) in patients suffering from chronic heart failure are reversed in patients treated with beta-adrenoceptor antagonist.

  2002cites this paper
• Effects of pimobendan on adverse cardiac events and physical activities in patients with mild to moderate chronic heart failure: the effects of pimobendan on chronic heart failure study (EPOCH study).

  2002cites this paper
• Coronary Microembolization: the Role of TNF- α in Contractile Dysfunction

  2002cites this paper
• Who are the enemies? Inflammation and autoimmune mechanisms

  2002cites this paper
• Effects of Growth Hormone Administration on Plasma Levels of Proinflammatory Cytokines and Soluble Apoptosis Mediators Fas/FasLigand in Patients with Dilated Cardiomyopathy

  2002cites this paper
• Growth hormone administration reduces circulating proinflammatory cytokines and soluble Fas/soluble Fas ligand system in patients with chronic heart failure secondary to idiopathic dilated cardiomyopathy.

  2002cites this paper
• Failure-Adrenergic Hyporesponsiveness in Rats With Experimental Volume-Overload Heart β Role of Myocardial Inducible Nitric Oxide Synthase in Contractile Dysfunction and

  2001cites this paper
• The Role of Inflammatory Mediators in the Failing Heart: Immunomodulation of Cytokines in Experimental Models of Heart Failure

  2001cites this paper
• Impaired beta-adrenergic control of immune function in patients with chronic heart failure: reversal by beta1-blocker treatment.

  2001cites this paper
• Myocardial gene expression of leukaemia inhibitory factor, interleukin‐6 and glycoprotein 130 in end‐stage human heart failure

  2001cites this paper
• Impaired β-adrenergic control of immune function in patients with chronic heart failure: reversal by β1-blocker treatment

  2001cites this paper
• Immunomodulation of Cytokines in Experimental Models of Heart Failure

  2001cites this paper
• A glossary of circulating cytokines in chronic heart failure

  2001cites this paper
• Plasma bradykinin levels in human chronic congestive heart failure.

  2000cites this paper
• Cellular events linked to cardiac remodeling in heart failure: targets for pharmacologic intervention.

  2000cites this paper
• Aldosterone and spironolactone in heart failure.

  1999cites this paper
• TNF-alpha in patients with chronic failure is not only a proinflammatory cytokine.

  1999cites this paper
• TNF-α in patients with chronic failure is not only a proinflammatory cytokine

  1999cites this paper