The C‐type natriuretic peptide precursor of snake brain contains highly specific inhibitors of the angiotensin‐converting enzyme

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Journal of Neurochemistry

• Publication date

  2003-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1046/j.1471-4159.2003.01743.xPMID 12716428
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Selective inhibition of the C-domain of angiotensin I converting enzyme by bradykinin potentiating peptides.

  2002influential reference
• Neural Pathways From The Lamina Terminalis Influencing Cardiovascular And Body Fluid Homeostasis

  2001influential reference
• Expression of endo-oligopeptidase A in the rat central nervous system: a non-radioactive in situ hybridization study.

  2001cited by this paper
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  2000cited by this paper
• Natriuretic peptides and their therapeutic potential.

  1999cited by this paper
• lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS.

  1999cited by this paper
• RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites.

  1999cited by this paper
• Design of angiotensin converting enzyme inhibitors

  1999cited by this paper
• Changes in the secretory activity of the subcommissural organ of spontaneously hypertensive rats.

  1998cited by this paper
• N-domain-specific substrate and C-domain inhibitors of angiotensin-converting enzyme: angiotensin-(1-7) and keto-ACE.

  1998cited by this paper
• The subcommissural organ

  1998cited by this paper
• Cloning of an unusual natriuretic peptide from the South American coral snake Micrurus corallinus.

  1997cited by this paper
• Cloning and sequence analysis of a Bothrops jararaca cDNA encoding a precursor of seven bradykinin-potentiating peptides and a C-type natriuretic peptide.

  1997influential reference
• Potentiation of the actions of bradykinin by angiotensin I-converting enzyme inhibitors. The role of expressed human bradykinin B2 receptors and angiotensin I-converting enzyme in CHO cells.

  1997cited by this paper
• Molecular biology and genetics of the angiotensin-I-converting enzyme: potential implications in cardiovascular diseases.

  1996cited by this paper
• Nerve growth factors from snake venoms: chemical properties, mode of action and biological significance.

  1996cited by this paper
• Inhibition of angiotensin converting enzyme and potentiation of bradykinin by retro-inverso analogues of short peptides and sequences related to angiotensin I and bradykinin.

  1996cited by this paper
• Internally quenched fluorogenic protease substrates: Solid-phase synthesis and fluorescence spectroscopy of peptides containing ortho-aminobenzoyl/dinitrophenyl groups as donor-acceptor pairs

  1995cited by this paper
• Localization of angiotensin converting enzyme by in vitro autoradiography in the rabbit brain.

  1995cited by this paper
• C-type natriuretic peptide. An endogenous inhibitor of vascular angiotensin-converting enzyme activity.

  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• Differences in the properties and enzymatic specificities of the two active sites of angiotensin I-converting enzyme (kininase II). Studies with bradykinin and other natural peptides.

  1993cited by this paper
• Cloning and Sequence Analysis of cDNAs Encoding Precursors of Sarafotoxins

  1993cited by this paper
• Cloning and sequence analysis of cDNAs encoding precursors of sarafotoxins. Evidence for an unusual "rosary-type" organization.

  1993cited by this paper
• The two homologous domains of human angiotensin I-converting enzyme are both catalytically active.

  1991influential reference
• Angiotensin converting enzyme in the human basal forebrain and midbrain visualized by in vitro autoradiography

  1990cited by this paper
• Inhibition of tissue angiotensin converting enzyme. Quantitation by autoradiography.

  1988cited by this paper
• Angiotensin II specific receptors in subcommissural organ.

  1988cited by this paper
• Guidelines for the use of Animals in Biomedical Research

  1987cited by this paper
• Angiotensin converting enzyme in rat brain visualized by quantitative in vitro autoradiography.

  1987cited by this paper
• Converting enzyme inhibition and modulation of plasma renin activity with captopril in anesthetized rats.

  1981influential reference
• 2 Inhibitiors of Angiotensin-Converting Enzyme

  1980cited by this paper
• Reduction of pressor effects of angiotensin I in man by synthetic nonapeptide (B.P.P. 9a or SQ 20,881) which inhibits converting enzyme.

  1973cited by this paper
• Inhibition of the Conversion of Angiotensin I to II and Potentiation of Bradykinin by Small Peptides Present in Bothrops jararaca Venom

  1972cited by this paper
• Action of bradykinin potentiating factor (BPF) and dimercaprol (BAL) on the responses to bradykinin of isolated preparations of rat intestines

  1971cited by this paper
• Isolation of bradykinin-potentiating peptides from Bothrops jararaca venom.

  1970cited by this paper
• Bradykinin, a hypotensive and smooth muscle stimulating factor released from plasma globulin by snake venoms and by trypsin.

  1949cited by this paper

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