Identification and characterization of a previously undescribed family of sequence-specific DNA-binding domains

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2013-04-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/pnas.1221734110PMID 23610392PMCID PMC3651432
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Conserved Transcriptional Regulator Governs Fungal Morphology in Widely Diverged Species

  2012cited by this paper
• Protein data bank

  2012cited by this paper
• Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses

  2012cited by this paper
• Genome sequence of Wickerhamomyces anomalus DSM 6766 reveals genetic basis of biotechnologically important antimicrobial activities.

  2012cited by this paper
• Proto-genes and de novo gene birth

  2012cited by this paper
• A recently evolved transcriptional network controls biofilm development in Candida albicans.

  2012cited by this paper
• Candida albicans Zcf37, a zinc finger protein, is required for stabilization of the white state

  2011cited by this paper
• Target specificity of the Candida albicans Efg1 regulator

  2011cited by this paper
• Survey of Branch Support Methods Demonstrates Accuracy, Power, and Robustness of Fast Likelihood-based Approximation Schemes

  2011cited by this paper
• MochiView: versatile software for genome browsing and DNA motif analysis

  2010influential reference
• The Transcriptomes of Two Heritable Cell Types Illuminate the Circuit Governing Their Differentiation

  2010cited by this paper
• New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0.

  2010cited by this paper
• Regulation of white-opaque switching in Candida albicans

  2010cited by this paper
• Distinct class of DNA-binding domains is exemplified by a master regulator of phenotypic switching in Candida albicans

  2010cited by this paper
• Genetics and molecular biology in Candida albicans.

  2010cited by this paper
• De Novo Identification and Biophysical Characterization of Transcription Factor Binding Sites with Microfluidic Affinity Analysis

  2010cited by this paper
• A Phenotypic Profile of the Candida albicans Regulatory Network

  2009cited by this paper
• White-opaque switching in Candida albicans.

  2009cited by this paper
• Why does Candida albicans switch?

  2009cited by this paper
• Dynamics of the interlocked positive feedback loops explaining the robust epigenetic switching in Candida albicans.

  2009cited by this paper
• Differential Phagocytosis of White versus Opaque Candida albicans by Drosophila and Mouse Phagocytes

  2008cited by this paper
• The Evolution of Combinatorial Gene Regulation in Fungi

  2008cited by this paper
• The morphogenetic regulator Czf1p is a DNA-binding protein that regulates white opaque switching in Candida albicans.

  2007cited by this paper
• Natural history and evolutionary principles of gene duplication in fungi

  2007cited by this paper
• Interlocking Transcriptional Feedback Loops Control White-Opaque Switching in Candida albicans

  2007influential reference
• A Systems Approach to Measuring the Binding Energy Landscapes of Transcription Factors

  2007cited by this paper
• Epigenetic properties of white–opaque switching in Candida albicans are based on a self-sustaining transcriptional feedback loop

  2006influential reference
• Dating divergences in the Fungal Tree of Life: review and new analyses.

  2006influential reference
• Design of a combinatorial DNA microarray for protein-DNA interaction studies

  2006cited by this paper
• Design of a combinatorial DNA microarray for protein-DNA interaction studies

  2006cited by this paper
• Goulphar: rapid access and expertise for standard two-color microarray normalization methods

  2006cited by this paper
• The HHpred interactive server for protein homology detection and structure prediction

  2005cited by this paper
• Release of a Potent Polymorphonuclear Leukocyte Chemoattractant Is Regulated by White-Opaque Switching in Candida albicans

  2004cited by this paper
• Attributable mortality of nosocomial candidemia, revisited.

  2003cited by this paper
• Evolution of a combinatorial transcriptional circuit: a case study in yeasts.

  2003cited by this paper
• Epidemiology of Candida species infections in critically ill non-immunosuppressed patients.

  2003cited by this paper
• White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating.

  2002cited by this paper
• Metabolic specialization associated with phenotypic switching in Candida albicans

  2002cited by this paper
• Genomic BLAST: custom-defined virtual databases for complete and unfinished genomes.

  2002cited by this paper
• The Protein Data Bank

  2000cited by this paper
• Misexpression of the Opaque-Phase-Specific GenePEP1 (SAP1) in the White Phase of Candida albicans Confers Increased Virulence in a Mouse Model of Cutaneous Infection

  1999cited by this paper
• Misexpression of the white-phase-specific gene WH11 in the opaque phase of Candida albicans affects switching and virulence

  1997cited by this paper
• SCOP: a structural classification of proteins database for the investigation of sequences and structures.

  1995cited by this paper
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• High-frequency phenotypic switching in Candida albicans.

  1993cited by this paper
• Opaque-white phenotype transition: a programmed morphological transition in Candida albicans

  1988cited by this paper
• Hospital-acquired candidemia. The attributable mortality and excess length of stay.

  1988cited by this paper
• "White-opaque transition": a second high-frequency switching system in Candida albicans

  1987cited by this paper
• Identification and Characterization of a Candida albicans Mating Pheromone

  year unknowncited by this paper

• Transcriptional control of C. albicans white-opaque switching and modulation by environmental cues and strain background

  2025cites this paper
• Genetic and environmental control of parasexual reproduction in the pathogenic Candida species

  2025cites this paper
• Gene dosage and protein valency impact phase separation and fungal cell fate

  2025cites this paper
• White-opaque switching in Candida albicans: cell biology, regulation, and function

  2024cites this paper
• The transcription factor Ofi1 is critical for white‐opaque switching in natural MTLa/α isolates of Candida albicans

  2024cites this paper
• Reinforcement amid genetic diversity in the Candida albicans biofilm regulatory network

  2023cites this paper
• Farnesol and phosphorylation of the transcriptional regulator Efg1 affect Candida albicans white-opaque switching rates

  2023cites this paper
• Morphogenic plasticity: the pathogenic attribute of Candida albicans

  2023cites this paper
• Morphogenetic transitions in the adaptation of Candida albicans to the mammalian gut.

  2023cites this paper
• Variation in transcription regulator expression underlies differences in white-opaque switching between the SC5314 reference strain and the majority of Candida albicans clinical isolates.

  2023cites this paper
• Fun30 nucleosome remodeller regulates white-to-opaque switching in Candida albicans

  2023cites this paper
• Principles of protein–DNA recognition

  2022cites this paper
• Role of the WOR1 Promoter of Candida albicans in Opaque Commitment

  2021cites this paper
• Imaging and Quantification of mRNA Molecules at Single-Cell Resolution in the Human Fungal Pathogen <named-content content-type='genus-species'>Candida albicans</named-content>

  2021cites this paper
• The Roles of Chromatin Accessibility in Regulating the Candida albicans White-Opaque Phenotypic Switch

  2021influential citation
• Comparative genomics of white and opaque cell states supports an epigenetic mechanism of phenotypic switching in Candida albicans

  2021cites this paper
• Recording of DNA-binding events reveals the importance of a repurposed Candida albicans regulatory network for gut commensalism.

  2021cites this paper
• Imaging and Quantification of mRNA Molecules at Single-Cell Resolution in the Human Fungal Pathogen Candida albicans

  2021cites this paper
• Overexpression approaches to advance understanding of Candida albicans

  2021cites this paper
• BbWor1, a Regulator of Morphological Transition, Is Involved in Conidium-Hypha Switching, Blastospore Propagation, and Virulence in Beauveria bassiana

  2021cites this paper
• Recording of DNA binding events during gut commensalism reveals the action of a repurposed Candida albicans regulatory network

  2020cites this paper
• An Opaque Cell-Specific Expression Program of Secreted Proteases and Transporters Allows Cell-Type Cooperation in Candida albicans

  2020cites this paper
• Wor1‐regulated ferroxidases contribute to pigment formation in opaque cells of Candida albicans

  2020cites this paper
• Transcriptional Circuits Regulating Developmental Processes in Candida albicans

  2020cites this paper
• Evolution of the complex transcription network controlling biofilm formation in Candida species

  2020cites this paper
• Candida albicans Double Mutants Lacking both EFG1 and WOR1 Can Still Switch to Opaque

  2020influential citation
• Epigenetic Cell Fate in Candida albicans is Controlled by Transcription Factor Condensates Acting at Super-Enhancer-Like Elements

  2020cites this paper
• A Set of Diverse Genes Influence the Frequency of White-Opaque Switching in Candida albicans

  2020cites this paper
• Monitoring Phenotypic Switching in Candida albicans and the Use of Next‐Gen Fluorescence Reporters

  2019cites this paper
• Roles of the Transcription Factors Sfl2 and Efg1 in White-Opaque Switching in a/α Strains of Candida albicans

  2019cites this paper
• Hemizygosity Enables a Mutational Transition Governing Fungal Virulence and Commensalism.

  2019cites this paper
• Probing recalcitrant problems in polyclad evolution and systematics with novel mitochondrial genome resources.

  2019cites this paper
• Role of Candida albicans mating in genetic variability and adaptation to the host

  2019cites this paper
• Microfluidic epigenomic mapping technologies for precision medicine.

  2019cites this paper
• Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1 in Candida albicans

  2018cites this paper
• Etude de la dégénérescence cellulaire épigénétique Crippled Growth chez le champignon Podospora anserina

  2018cites this paper
• Intrinsic cooperativity potentiates parallel cis-regulatory evolution

  2018cites this paper
• Morphogenesis in C. albicans

  2017cites this paper
• Optimized Sequence Library Design for Efficient In Vitro Interaction Mapping.

  2017cites this paper
• Genome-wide functional analysis in Candida albicans

  2017cites this paper
• Ras signalling in pathogenic yeasts

  2017cites this paper
• Gene regulatory network plasticity predates a switch in function of a conserved transcription regulator

  2017cites this paper
• The yeast form of the fungus Candida albicans promotes persistence in the gut of gnotobiotic mice

  2017cites this paper
• Epigenetic determinants of phenotypic plasticity in Candida albicans

  2017cites this paper
• Mechanically Induced Trapping of Molecular Interactions and Its Applications

  2016cites this paper
• Systematic Genetic Screen for Transcriptional Regulators of the Candida albicans White-Opaque Switch

  2016influential citation
• Genome-Wide Chromatin Immunoprecipitation in Candida albicans and Other Yeasts.

  2016cites this paper
• Ssn6 Defines a New Level of Regulation of White-Opaque Switching in Candida albicans and Is Required For the Stochasticity of the Switch

  2016influential citation
• Budding off: bringing functional genomics to Candida albicans.

  2016cites this paper
• Identification and Characterization of Wor4, a New Transcriptional Regulator of White-Opaque Switching

  2016cites this paper
• A Multistate Toggle Switch Defines Fungal Cell Fates and Is Regulated by Synergistic Genetic Cues

  2016cites this paper
• Transcriptional rewiring over evolutionary timescales changes quantitative and qualitative properties of gene expression

  2016cites this paper
• Transcriptional Control of Drug Resistance, Virulence and Immune System Evasion in Pathogenic Fungi: A Cross-Species Comparison

  2016influential citation
• Candida albicans cell-type switching and functional plasticity in the mammalian host

  2016cites this paper
• Global Identification of Biofilm-Specific Proteolysis in Candida albicans

  2016cites this paper
• Binding Sites in the EFG1 Promoter for Transcription Factors in a Proposed Regulatory Network: A Functional Analysis in the White and Opaque Phases of Candida albicans

  2016influential citation
• Independent Emergence of Complex Multicellularity in the Brown and Red Algae

  2015cites this paper
• The WOR 1 5′ untranslated region regulates white‐opaque switching in C andida albicans by reducing translational efficiency

  2015cites this paper
• Hypoxia and Temperature Regulated Morphogenesis in Candida albicans

  2015cites this paper
• The WOR1 5' untranslated region regulates white-opaque switching in Candida albicans by reducing translational efficiency

  2015cites this paper
• Phenotypic characterisation of Candida albicans mutants with deletions of arachidonic acid responsive genes

  2015cites this paper
• Candida survival strategies.

  2015cites this paper
• The role of phenotypic switching in the basic biology and pathogenesis of Candida albicans

  2014cites this paper
• Epigenetic Regulation of White-Opaque Switching in Candida albicans

  2014cites this paper
• How duplicated transcription regulators can diversify to govern the expression of nonoverlapping sets of genes

  2014cites this paper
• Sexual biofilm formation in Candida tropicalis opaque cells

  2014cites this paper
• A Novel Function for Hog1 Stress-Activated Protein Kinase in Controlling White-Opaque Switching and Mating in Candida albicans

  2014cites this paper
• The rosetteless gene controls development in the choanoflagellate S. rosetta

  2014cites this paper
• Functional analysis of the conserved transcriptional regulator CfWor1 in Cladosporium fulvum reveals diverse roles in the virulence of plant pathogenic fungi

  2014cites this paper
• A confounding effect of missing data on character conflict in maximum likelihood and Bayesian MCMC phylogenetic analyses.

  2014cites this paper
• Ras Signaling Gets Fine-Tuned: Regulation of Multiple Pathogenic Traits of Candida albicans

  2013cites this paper
• Differential Regulation of White-Opaque Switching by Individual Subunits of Candida albicans Mediator

  2013cites this paper
• Transcription factor evolution in eukaryotes and the assembly of the regulatory toolkit in multicellular lineages

  2013cites this paper
• Structure of the transcriptional network controlling white‐opaque switching in Candida albicans

  2013influential citation
• The APSES transcription factor Efg1 is a global regulator that controls morphogenesis and biofilm formation in Candida parapsilosis

  2013cites this paper