Depression and anxiety disorders among gastroenterologic outpatients

I. Tasci,U. Safer

Published 2014 in Saudi Journal of Gastroenterology

ABSTRACT

Studies have shown that subjects with depression have altered secretion of ghrelin, a well‐characterized, a p p e t i t e ‐ s t i m u l a t i n g h o r m o n e p r o d u c e d i n gastrointestinal system. Although blood ghrelin response is diminished after meal in untreated subjects with depression, it increases after appropriate antidepressive treatment.[1,2] Moreover, gastrointestinal hormones, including leptin and ghrelin, also have systemic effects, and their metabolism is altered in certain gastrointestinal system disorders.[3]

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