β‐Catenin and interleukin‐1β–dependent chemokine (C‐X‐C motif) ligand 10 production drives progression of disease in a mouse model of congenital hepatic fibrosis

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Hepatology

• Publication date

  2018-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/hep.29652PMID 29140564PMCID PMC5906178
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2005influential reference
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  2000cited by this paper
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• Molecular Pathogenesis of Genetic and Inherited Diseases Biliary and Pancreatic Dysgenesis in Mice Harboring a Mutation in Pkhd1

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