Cr(IV) causes activation of nuclear transcription factor-kappa B, DNA strand breaks and dG hydroxylation via free radical reactions.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of Inorganic Biochemistry

• Publication date

  1999-05-30

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/S0162-0134(99)00030-6PMID 10402675
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Role of hydroxyl radical in silica-induced NF-kappa B activation in macrophages.

  1998cited by this paper
• Synthesis of Cr(IV)-GSH, its identification and its free hydroxyl radical generation: a model compound for Cr(VI) carcinogenicity.

  1997cited by this paper
• One-Electron Reduction of Chromium(VI) by α-Lipoic Acid and Related Hydroxyl Radical Generation, dG Hydroxylation and Nuclear Transcription Factor-κB Activation

  1997cited by this paper
• One-electron reduction of chromium(VI) by alpha-lipoic acid and related hydroxyl radical generation, dG hydroxylation and nuclear transcription factor-kappaB activation.

  1997cited by this paper
• THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

  1996cited by this paper
• The NF-kappa B and I kappa B proteins: new discoveries and insights.

  1996cited by this paper
• Redox regulation of transcriptional activators.

  1996cited by this paper
• Chromium(VI)-induced nuclear factor-kappa B activation in intact cells via free radical reactions.

  1995cited by this paper
• Generation of Reactive Oxygen Species by Quartz Particles and Its Implication for Cellular Damage

  1995cited by this paper
• Chromium(VI)-induced nuclear factor-кB activation in intact cells via free radical reactions

  1995cited by this paper
• Chromate-induced chromium(V) formation in live mice and its control by cellular antioxidants: an L-band electron paramagnetic resonance study.

  1995cited by this paper
• Reaction of Cr(VI) with ascorbate and hydrogen peroxide generates hydroxyl radicals and causes DNA damage: role of a Cr(IV)-mediated Fenton-like reaction.

  1994cited by this paper
• Generation of hydroxyl radical by chromate in biologically relevant systems: role of Cr(V) complexes versus tetraperoxochromate(V).

  1994cited by this paper
• Low-frequency EPR detection of chromium(V) formation by chromium(VI) reduction in whole live mice.

  1994cited by this paper
• Function and activation of NF-kappa B in the immune system.

  1994cited by this paper
• Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: case-control study of subjects participating in the Nottingham faecal occult blood screening programme.

  1993cited by this paper
• Aspirin use and risk of fatal cancer.

  1993cited by this paper
• Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review).

  1992cited by this paper
• Deferoxamine inhibition of Cr(V)-mediated radical generation and deoxyguanine hydroxylation: ESR and HPLC evidence.

  1992cited by this paper
• The role of superoxide radical in chromium (VI)-generated hydroxyl radical: the Cr(VI) Haber-Weiss cycle.

  1992cited by this paper
• Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

  1991cited by this paper
• Formation of 8-hydroxy(deoxy)guanosine and generation of strand breaks at guanine residues in DNA by singlet oxygen.

  1991cited by this paper
• Chromium cycling in soils and water: links, gaps, and methods.

  1991cited by this paper
• Aspirin use and reduced risk of fatal colon cancer.

  1991cited by this paper
• Oral bioavailability of chromium from a specific site.

  1991cited by this paper
• On the hydroxyl radical formation in the reaction between hydrogen peroxide and biologically generated chromium(V) species.

  1990cited by this paper
• Genotoxicity of chromium compounds. A review.

  1990cited by this paper
• The role of 8-hydroxyguanine in carcinogenesis.

  1990cited by this paper
• Copper, zinc superoxide dismutase catalyzes hydroxyl radical production from hydrogen peroxide.

  1990cited by this paper
• ESR evidence for superoxide, hydroxyl radicals and singlet oxygen produced from hydrogen peroxide and nickel(II) complex of glycylglycyl-L-histidine.

  1989cited by this paper
• Chromium (V) and hydroxyl radical formation during the glutathione reductase-catalyzed reduction of chromium (VI).

  1989cited by this paper
• Hydroxyl free radical mediated formation of 8-hydroxyguanine in isolated DNA.

  1988cited by this paper
• Spin trapping: ESR parameters of spin adducts.

  1987cited by this paper
• The interaction of chromium with nucleic acids.

  1983cited by this paper
• Microsomal reduction of the carcinogen chromate produces chromium(V)

  1982cited by this paper

• Association between size-resolved PM10-bound heavy metal and metalloid exposure and oxidative stress among waste recycling workers

  2025cites this paper
• Interactions between chromium species and DNA in vitro and their potential role in the toxicity of hexavalent chromium.

  2023cites this paper
• Chromium [Cr(VI)] Exposure Causes Cytotoxicity of Human Bronchial Epithelial Cells (16-HBE) and Proteomic Alterations

  2022cites this paper
• p62 functions as a signal hub in metal carcinogenesis.

  2021cites this paper
• One Environmental Health: an emerging perspective in toxicology

  2018cites this paper
• Melatonin protects against chromium (VI) induced hepatic oxidative stress and toxicity: Duration dependent study with realistic dosage

  2017cites this paper
• Recent aspects of uranium toxicology in medical geology

  2017cites this paper
• Trace Mineral Overload Induced Hepatic Oxidative Damage and Apoptosis in Pigs with Long-Term High-Level Dietary Mineral Exposure.

  2016cites this paper
• Chromium(VI) compounds (inhalable fraction) [MAK Value Documentation, 2012]

  2016cites this paper
• Gallic acid attenuates chromium-induced thyroid dysfunction by modulating antioxidant status and inflammatory cytokines.

  2016cites this paper
• Chapter 33 – Chromium

  2015cites this paper
• Efecto protector in vivo de eucalyptus globulus labill “eucalipto” frente al daño genotóxico inducido por ciclofosfamida en leucocitos y células hepáticas de rattus novergicus cepa holtzman

  2015cites this paper
• [IN VIVO EFFECT OF RED WINE UNDILUTED, DILUTED (75%) AND ALCOHOL-FREE ON THE GENOTOXIC DAMAGE INDUCED BY POTENTIAL CARCINOGENIC METALS: CHROMIUM [VI]].

  2015cites this paper
• Room temperature quantum coherence in a potential molecular qubit

  2014cites this paper
• Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways.

  2014cites this paper
• DNA damage by oxo- and peroxo-chromium(V) complexes: insight into the mutation and carcinogenesis mechanisms

  2014cites this paper
• Chromium-induced nephrotoxicity and ameliorative effect of carvedilol in rats: Involvement of oxidative stress, apoptosis and inflammation.

  2014cites this paper
• Impact of hexavalent chromium on mammalian cell bioenergetics: phenotypic changes, molecular basis and potential relevance to chromate-induced lung cancer

  2014cites this paper
• Possible Effects of Metallosis on Spermatozoal Apoptotic Genes Expression in Individuals with Intramedullary Nailing Prosthesis

  2014cites this paper
• The distribution and pro-inflammatory impact of titanium debris accumulation in the peri-implant environment

  2014cites this paper
• Kinetics and mechanism of the oxidation of N-acetyl homocysteine thiolactone with aqueous iodine and iodate.

  2013cites this paper
• Strategies for chromium bioremediation of tannery effluent.

  2012cites this paper
• The effects of chromium(VI) on the thioredoxin system: implications for redox regulation.

  2012cites this paper
• Reviews of Environmental Contamination and Toxicology Volume 217

  2012cites this paper
• High‐Valent Cr, Mn, and Fe Species

  2012cites this paper
• Cancer stem cells in the mechanism of metal carcinogenesis.

  2012cites this paper
• Biologic Implications from an Epidemiologic Study of Chromate Production Workers

  2011cites this paper
• The intracellular redox stress caused by hexavalent chromium is selective for proteins that have key roles in cell survival and thiol redox control.

  2011cites this paper
• Response of antioxidant defense system to chromium (VI)-induced cytotoxicity in human diploid cells

  2010cites this paper
• Review of Chromium (VI) Apoptosis, Cell-Cycle-Arrest, and Carcinogenesis

  2010cites this paper
• The pro-oxidant chromium(VI) inhibits mitochondrial complex I, complex II, and aconitase in the bronchial epithelium: EPR markers for Fe-S proteins.

  2010cites this paper
• The effects of hexavalent chromium on thioredoxin reductase and peroxiredoxins in human bronchial epithelial cells.

  2009cites this paper
• The effects of feeding with different levels of zinc and chromium on plasma thiobarbituric acid reactive substances and antioxidant enzymes in rats.

  2009cites this paper
• Hexavalent chromium causes the oxidation of thioredoxin in human bronchial epithelial cells.

  2008cites this paper
• Addition of DNA to CrVI and Cytochrome b5 Containing Proteoliposomes Leads to Generation of DNA Strand Breaks and CrIII Complexes

  2008cites this paper
• Reductive activation of hexavalent chromium by human lung epithelial cells: generation of Cr(V) and Cr(V)-thiol species.

  2008cites this paper
• HCaRG "Hypertension-related Calcium Regulated Gene", un gène candidat de la réparation rénale : caractérisation de son interaction avec le cytosquelette et son expression génique

  2008cites this paper
• Reduction of hexavalent chromium by human cytochrome b5: generation of hydroxyl radical and superoxide.

  2007cites this paper
• Vapour phase oxidation of tetralin over Cr and Fe substituted MCM-41 molecular sieves

  2007cites this paper
• Effect of curcumin on chromium-induced oxidative damage in male reproductive system.

  2007cites this paper
• Mechanisms of DNA damage and insight into mutations by chromium(VI) in the presence of glutathione.

  2007cites this paper
• CHAPTER 24 – Chromium

  2007cites this paper
• Hip implants – Paper VI – Ion concentrations

  2007cites this paper
• Lower mutagenicity but higher stability of Cr-DNA adducts formed during gradual chromate activation with ascorbate.

  2006cites this paper
• Involvement of the p38 MAP kinase in Cr(VI)-induced growth arrest and apoptosis

  2005cites this paper
• Construction of a subtractive library from hexavalent chromium treated winter flounder (Pseudopleuronectes americanus) reveals alterations in non-selenium glutathione peroxidases.

  2004cites this paper
• The ATM-SMC1 pathway is essential for activation of the chromium[VI]-induced S-phase checkpoint.

  2004cites this paper
• Status of antioxidant defense system in chromium-induced Swiss mice tissues.

  2004cites this paper
• Metal-induced toxicity, carcinogenesis, mechanisms and cellular responses

  2004cites this paper
• Model reactions of Cr (VI) with DNA mediated by thiol species

  2004cites this paper
• PbCrO4 mediates cellular responses via reactive oxygen species

  2004cites this paper
• Activation of c-Jun N-terminal kinase in A549 lung carcinoma cells by sodium dichromate: role of dissociation of apoptosis signal regulating kinase-1 from its physiological inhibitor thioredoxin.

  2004cites this paper
• Arsenite causes DNA damage in keratinocytes via generation of hydroxyl radicals.

  2004cites this paper
• Role of reactive oxygen species and Cr(VI) in Ras-mediated signal transduction

  2004cites this paper
• Crystalline and water soluble CR(4+) and CR(5+:) model compounds for chromium toxicity studies

  2004cites this paper
• Micellar effect on the kinetics and mechanism of chromium(VI) oxidation of organic substrates

  2004cites this paper
• Complexities of chromium carcinogenesis: role of cellular response, repair and recovery mechanisms.

  2003cites this paper
• Oxidative Stress, hogg1 Expression and NF‐κB Activity in Cells Exposed to Low Level Chromium

  2003cites this paper
• p38 Signaling-mediated Hypoxia-inducible Factor 1α and Vascular Endothelial Growth Factor Induction by Cr(VI) in DU145 Human Prostate Carcinoma Cells*

  2002cites this paper
• DNA oxidation by peroxo-chromium(v) species: oxidation of guanosine to guanidinohydantoin.

  2002cites this paper
• Down-regulation of the DNA-repair endonuclease 8-oxo-guanine DNA glycosylase 1 (hOGG1) by sodium dichromate in cultured human A549 lung carcinoma cells.

  2002cites this paper
• Redox-modulated pathways in inflammatory skin diseases.

  2001cites this paper
• Reduction of Cr(VI) by cysteine: Significance in human lymphocytes and formation of DNA damage in reactions with variable reduction rates

  2001cites this paper
• Detection of dichromate (VI)-induced DNA strand breaks and formation of paramagnetic chromium in multiple mouse organs.

  2001cites this paper
• Model reactions of Cr (VI) with DNA mediated by thiol species.

  2001cites this paper
• Redox Modulation and Oxidative Stress in Dermatotoxicology

  2001cites this paper
• Environmental Stressors in Health and Disease

  2001cites this paper
• Studies on the genotoxicity of chromium: from the test tube to the cell

  2001cites this paper
• Dermatotoxicology of Environmental and Occupational Chemical Hazards: Agents and Action

  2001cites this paper
• Effect of Cr(VI) exposure on sperm quality: human and animal studies.

  2001cites this paper
• Molecular mechanisms of metal toxicity and carcinogenesis

  2001cites this paper
• In vivo reduction of chromium (VI) and its related free radical generation

  2001cites this paper
• The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation.

  2000cites this paper
• Antioxidant properties of (-)-epicatechin-3-gallate and its inhibition of Cr (VI)-induced DNA damage and Cr (IV)- or TPA-stimulated NF-κB activation

  2000cites this paper
• Anti-Aging Medicine LiteratureWatch

  1998cites this paper