Detection of metabolites of the new synthetic cannabinoid CUMYL-4CN-BINACA in authentic urine samples and human liver microsomes using high-resolution mass spectrometry.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Drug Testing and Analysis

• Publication date

  2018-03-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1002/dta.2248PMID 28691766
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phase I metabolism of the highly potent synthetic cannabinoid MDMB-CHMICA and detection in human urine samples.

  2017cited by this paper
• Elucidating the Mechanism of Tofacitinib Oxidative Decyanation.

  2016cited by this paper
• Identification and quantification of metabolites of AB-CHMINACA in a urine specimen of an abuser.

  2016cited by this paper
• Identification of AB-FUBINACA metabolites in authentic urine samples suitable as urinary markers of drug intake using liquid chromatography quadrupole tandem time of flight mass spectrometry.

  2016cited by this paper
• In vitro metabolism of a novel synthetic cannabinoid, EAM-2201, in human liver microsomes and human recombinant cytochrome P450s.

  2016cited by this paper
• In Vitro and In Vivo Human Metabolism of Synthetic Cannabinoids FDU-PB-22 and FUB-PB-22

  2016cited by this paper
• In vitro and in vivo human metabolism of the synthetic cannabinoid AB-CHMINACA.

  2015cited by this paper
• Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA

  2015cited by this paper
• Determination of major metabolites of MAM-2201 and JWH-122 in in vitro and in vivo studies to distinguish their intake.

  2014cited by this paper
• UPLC/ESI-MS/MS-based determination of metabolism of several new illicit drugs, ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC and α-PVT, by human liver microsome.

  2014cited by this paper
• Acute toxicity due to the confirmed consumption of synthetic cannabinoids: clinical and laboratory findings.

  2013cited by this paper
• First Characterization of AKB-48 Metabolism, a Novel Synthetic Cannabinoid, Using Human Hepatocytes and High-Resolution Mass Spectrometry

  2013cited by this paper
• Synthetic cannabinoid and marijuana exposures reported to poison centers

  2012cited by this paper
• Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation.

  2012cited by this paper
• Spice drugs are more than harmless herbal blends: a review of the pharmacology and toxicology of synthetic cannabinoids.

  2012cited by this paper
• Cyanohydrins in Nature and the Laboratory: Biology, Preparations, and Synthetic Applications.

  1999cited by this paper

• Synthetic Cannabinoid CUMYL-4CN-BINACA Induces Oxidative Stress, ER Stress, and Apoptosis in Brain and Testicular Tissues of Male Albino Rats.

  2025cites this paper
• Synthetic cannabinoid receptor agonists containing silicon: exploring the metabolic pathways of ADMB- and Cumyl-3TMS-PrINACA in human urine specimens and post mortem material compared to in vitro and in silico data

  2025cites this paper
• Developmental toxicity and gene expression alterations induced by the synthetic cannabinoid CUMYL-4CN-BINACA in zebrafish embryos.

  2025cites this paper
• In vitro metabolism of Benzyl-4CN-BUTINACA and MDMB-4CN-BUTINACA using human hepatocytes and LC-QToF-MS analysis

  2025cites this paper
• A study on the possible neurotoxic effects of CUMYL-4CN-BINACA in Sprague Dawley rats.

  2023cites this paper
• A Fatal Case Report Resulting from the Abuse of the Designer Benzodiazepines Clonazolam and Flualprazolam in Conjunction with Dried Opium Poppy Pods.

  2022cites this paper
• Changes in the frequency and pattern of drugs detected among suspected drug users during the COVID-19 pandemic in Turkey

  2022cites this paper
• Fourth generation of synthetic cannabinoid receptor agonists: A review on the latest insights.

  2021cites this paper
• Behavioral pharmacology of five novel synthetic cannabinoids

  2021cites this paper
• Interpol review of toxicology 2016–2019

  2020cites this paper
• In Vitro Metabolic Profile Elucidation of Synthetic Cannabinoid APP-CHMINACA (PX-3).

  2020cites this paper
• In Vitro Phase I Metabolism of the Recently Emerged Synthetic MDMB-4en-PINACA and its Detection in Human Urine Samples.

  2020cites this paper
• Determination of Third Generation Synthetic Cannabinoids in Oral Fluids.

  2020cites this paper
• Agent with Doping Effects That are Prohibited for the Use of Athletes

  2020cites this paper
• Exploring Stereochemical and Conformational Requirements at Cannabinoid Receptors for Synthetic Cannabinoids Related to SDB-006, 5F-SDB-006, CUMYL-PICA, and 5F-CUMYL-PICA.

  2020cites this paper
• Study of the in vitro and in vivo metabolism of a novel synthetic cannabinoid PX-2 in human liver microsomes and zebrafish

  2020cites this paper
• New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites

  2019cites this paper
• CUMYL-4CN-BINACA Is an Efficacious and Potent Pro-Convulsant Synthetic Cannabinoid Receptor Agonist

  2019cites this paper
• Solid-phase extraction-liquid chromatography-tandem mass spectrometry method for the qualitative analysis of 61 synthetic cannabinoid metabolites in urine.

  2019cites this paper
• Metabolic profiling of synthetic cannabinoid 5F-ADB by human liver microsome incubations and urine samples using high-resolution mass spectrometry.

  2019cites this paper
• In vitro Phase I metabolism of indazole carboxamide synthetic cannabinoid MDMB-CHMINACA via human liver microsome incubation and high-resolution mass spectrometry.

  2019cites this paper
• Metabolism of the new synthetic cannabinoid EG-018 in human hepatocytes by high-resolution mass spectrometry

  2018cites this paper
• Phase I metabolism of the recently emerged synthetic cannabinoid CUMYL-PEGACLONE and detection in human urine samples.

  2018cites this paper
• Metabolism study for CUMYL-4CN-BINACA in human hepatocytes and authentic urine specimens: Free cyanide is formed during the main metabolic pathway.

  2018cites this paper
• Report on the risk assessment of 1-(4-Cyanobutyl)-N-(2-phenylpropan-2-yl)- 1H-indazole-3-carboxamide in the framework of the Council Decision on new psychoactive substances

  2018influential citation
• 5F-Cumyl-PINACA in ‘e-liquids’ for electronic cigarettes: comprehensive characterization of a new type of synthetic cannabinoid in a trendy product including investigations on the in vitro and in vivo phase I metabolism of 5F-Cumyl-PINACA and its non-fluorinated analog Cumyl-PINACA

  2018cites this paper
• In vitro metabolism of the synthetic cannabinoids CUMYL-PINACA, 5F-CUMYL-PINACA, CUMYL-4CN-BINACA, 5F-CUMYL-P7AICA and CUMYL-4CN-B7AICA.

  2018cites this paper
• Structural characterization of the new synthetic cannabinoids CUMYL-PINACA, 5F-CUMYL-PINACA, CUMYL-4CN-BINACA, 5F-CUMYL-P7AICA and CUMYL-4CN-B7AICA.

  2017cites this paper