Selenocysteine-containing thioredoxin reductase in C. elegans.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  1999-06-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1006/BBRC.1999.0765PMID 10362494
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Comprehensive natural products chemistry

  1999cited by this paper
• Genome sequence of the nematode C-elegans: A platform for investigating biology

  1998cited by this paper
• Contrasting patterns of regulation of the antioxidant selenoproteins, thioredoxin reductase, and glutathione peroxidase, in cancer cells.

  1998cited by this paper
• Reduction of the Ascorbyl Free Radical to Ascorbate by Thioredoxin Reductase*

  1998cited by this paper
• Genome sequence of the nematode C. elegans: a platform for investigating biology.

  1998cited by this paper
• Human Placenta Thioredoxin Reductase

  1998cited by this paper
• Thioredoxin peroxidases from Brugia malayi.

  1998cited by this paper
• Human thioredoxin reductase from HeLa cells: selective alkylation of selenocysteine in the protein inhibits enzyme activity and reduction with NADPH influences affinity to heparin.

  1998cited by this paper
• Rat and Calf Thioredoxin Reductase Are Homologous to Glutathione Reductase with a Carboxyl-terminal Elongation Containing a Conserved Catalytically Active Penultimate Selenocysteine Residue*

  1998cited by this paper
• An essential non-Watson-Crick base pair motif in 3'UTR to mediate selenoprotein translation.

  1998cited by this paper
• Mammalian Thioredoxin Reductase Is Irreversibly Inhibited by Dinitrohalobenzenes by Alkylation of Both the Redox Active Selenocysteine and Its Neighboring Cysteine Residue*

  1998cited by this paper
• The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli.

  1997cited by this paper
• The path of unspecific incorporation of selenium in Escherichia coli

  1997cited by this paper
• Cell line-directed screening assay for inhibitors of thioredoxin reductase signaling as potential anti-cancer drugs.

  1997cited by this paper
• Thioredoxin reductase activity is decreased by selenium deficiency.

  1997cited by this paper
• Reduction of Dehydroascorbate to Ascorbate by the Selenoenzyme Thioredoxin Reductase*

  1997cited by this paper
• Knowing when not to stop: selenocysteine incorporation in eukaryotes.

  1996cited by this paper
• Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene.

  1996cited by this paper
• A selenium-containing phospholipid-hydroperoxide glutathione peroxidase in Schistosoma mansoni.

  1996cited by this paper
• 1-Chloro-2,4-dinitrobenzene Is an Irreversible Inhibitor of Human Thioredoxin Reductase

  1995cited by this paper
• Human Thioredoxin Reductase Directly Reduces Lipid Hydroperoxides by NADPH and Selenocystine Strongly Stimulates the Reaction via Catalytically Generated Selenols(*)

  1995cited by this paper
• Selenite and selenodiglutathione: reactions with thioredoxin systems.

  1995cited by this paper
• [22] Selenite and selenodiglutathione: Reactions with thioredoxin systems

  1995cited by this paper
• [21] Thioredoxin and thioredoxin reductase

  1995cited by this paper
• Thioredoxin and thioredoxin reductase.

  1995cited by this paper
• Cell cycle inhibition of HTLV-I transformed T cell lines by retinoic acid: the possible therapeutic use of thioredoxin reductase inhibitors.

  1995cited by this paper
• Cloning and sequencing of a human thioredoxin reductase

  1995cited by this paper
• The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase.

  1994cited by this paper
• Expression and operon structure of the sel genes of Escherichia coli and identification of a third selenium-containing formate dehydrogenase isoenzyme

  1991cited by this paper
• Recognition of UGA as a selenocysteine codon in Type I deiodinase requires sequences in the 3′ untranslated region

  1991cited by this paper
• Selenocysteine tRNA[Ser]Sec gene is ubiquitous within the animal kingdom

  1990cited by this paper
• Features of the formate dehydrogenase mRNA necessary for decoding of the UGA codon as selenocysteine.

  1990cited by this paper
• The Nematode Caenorhabditis elegans

  1988cited by this paper
• The genetics of Caenorhabditis elegans.

  1974cited by this paper

• Versatility of Caenorhabditis elegans as a Model Organism for Evaluating Foodborne Neurotoxins and Food Bioactive Compounds in Nutritional Neuroscience

  2025cites this paper
• Functional expression, localization, and biochemical characterization of thioredoxin glutathione reductase from air-breathing magur catfish, Clarias magur.

  2023cites this paper
• Sperm Redox System Equilibrium: Implications for Fertilization and Male Fertility.

  2022cites this paper
• Thiol antioxidant thioredoxin reductase: A prospective biochemical crossroads between anticancer and antiparasitic treatments of the modern era.

  2020cites this paper
• The glutathione system and the related thiol network in Caenorhabditis elegans

  2019cites this paper
• Redox Regulatory Circuits as Targets for Therapeutic Intervention of Bancroftian Filariasis: Biochemical, Molecular, and Pharmacological Perspectives

  2019cites this paper
• Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems.

  2019cites this paper
• A review on the druggability of a thiol-based enzymatic antioxidant thioredoxin reductase for treating filariasis and other parasitic infections.

  2019cites this paper
• Radioactive 75Se Labeling and Detection of Selenoproteins.

  2018cites this paper
• Selenium species-dependent toxicity, bioavailability and metabolic transformations in Caenorhabditis elegans.

  2018cites this paper
• Thioredoxin reductase from the bovine filarial parasite Setaria cervi: Studies on its localization and optimization of the extraction.

  2018cites this paper
• N-γ-(L-Glutamyl)-L-selenomethionine enhances stress resistance and ameliorates aging indicators via the selenoprotein TRXR-1 in Caenorhabditis elegans.

  2017cites this paper
• Synthesis of enantiomerically pure glycerol derivatives containing an organochalcogen unit: In vitro and in vivo antioxidant activity

  2017cites this paper
• Antagonistic Growth Effects of Mercury and Selenium in Caenorhabditis elegans Are Chemical-Species-Dependent and Do Not Depend on Internal Hg/Se Ratios.

  2016cites this paper
• Adjustments, extinction, and remains of selenocysteine incorporation machinery in the nematode lineage

  2014cites this paper
• Étude de la dynamique des interactions des constituants du complexe de biosynthèse et d’insertion de la sélénocystéine dans la traduction des sélénoprotéines in vivo

  2014cites this paper
• Why Is Mammalian Thioredoxin Reductase 1 So Dependent upon the Use of Selenium?

  2014cites this paper
• A Mechanistic Investigation of the C-Terminal Redox Motif of Thioredoxin Reductase from Plasmodium falciparum

  2014cites this paper
• Toxic-Selenium and Low-Selenium Transcriptomes in Caenorhabditis elegans: Toxic Selenium Up-Regulates Oxidoreductase and Down-Regulates Cuticle-Associated Genes

  2014cites this paper
• Seleno- and telluro-xylofuranosides attenuate Mn-induced toxicity in C. elegans via the DAF-16/FOXO pathway.

  2014cites this paper
• The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans?

  2014cites this paper
• Selenite protects Caenorhabditis elegans from oxidative stress via DAF-16 and TRXR-1.

  2014cites this paper
• Deletion of Thioredoxin Reductase and Effects of Selenite and Selenate Toxicity in Caenorhabditis elegans

  2013cites this paper
• Protective Efficacy of Selenite against Lead-Induced Neurotoxicity in Caenorhabditis elegans

  2013cites this paper
• Identification of GR and TrxR systems in Setaria cervi: Purification and characterization of glutathione reductase.

  2013cites this paper
• The Characterization of the Caenorhabditis elegans Mitochondrial Thioredoxin System Uncovers an Unexpected Protective Role of Thioredoxin Reductase 2 in β-Amyloid Peptide Toxicity

  2012cites this paper
• 1 LIFESPAN DECREASE IN A C . ELEGANS MUTANT LACKING TRX-1 , A THIOREDOXIN EXPRESSED IN ASJ SENSORY NEURONS

  2012cites this paper
• Two thioredoxin reductases, trxr-1 and trxr-2, have differential physiological roles in Caenorhabditis elegans

  2012cites this paper
• Characterization of selenium containing proteins in the coral Acropora millepora

  2011cites this paper
• Differing views of the role of selenium in thioredoxin reductase

  2011cites this paper
• The ameliorative and toxic effects of selenite on Caenorhabditis elegans.

  2011cites this paper
• Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans

  2011cites this paper
• Selenoproteins of the thioredoxin system

  2011cites this paper
• Reactive oxygen species: A radical role in development?

  2010cites this paper
• Substrate specificity of the mitochondrial thioredoxin reductase of the parasitic nematode Haemonchus contortus

  2010influential citation
• The Glutaredoxin GLRX-21 Functions to Prevent Selenium-Induced Oxidative Stress in Caenorhabditis elegans

  2010cites this paper
• Nuclear factor‐kappa B as a promising target for selenium chemoprevention in rat hepatocarcinogenesis

  2010cites this paper
• Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship?

  2010cites this paper
• Eukaryotic selenoproteins and selenoproteomes.

  2009cites this paper
• Comparative genomics of trace elements: emerging dynamic view of trace element utilization and function.

  2009cites this paper
• Refined annotation and assembly of the Tetrahymena thermophila genome sequence through EST analysis, comparative genomic hybridization, and targeted gap closure

  2008cites this paper
• INVESTIGATION INTO THE ROLE OF THE C-TERMINAL VICINAL CYSTEINE RESIDUES IN HIGH Mr THIOREDOXIN REDUCTASES

  2008influential citation
• INVESTIGATION INTO THE ROLE OF THE C-TERMINAL VICINAL CYSTEINE RESIDUES IN HIGH Mr THIOREDOXIN

  2008cites this paper
• Variation in the Selenoenzyme Genes and Risk of Advanced Distal Colorectal Adenoma

  2008cites this paper
• Mini R e view Oxidative stress and thioredoxin system

  2008cites this paper
• Oxidative stress and thioredoxin system.

  2008cites this paper
• Genetic and pharmacologic analysis of the mechanisms of selenium toxicity in Caenorhabditis elegans

  2008cites this paper
• Identification of Acid-Base Catalytic Residues of High-Mr Thioredoxin Reductase from Plasmodium falciparum*

  2006cites this paper
• Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX‐1, a thioredoxin expressed in ASJ sensory neurons

  2006cites this paper
• Selenoproteins in parasites

  2006cites this paper
• Role of IKKs and Transcription Factor NF-kB in Prostate Tumorigenesis

  2006cites this paper
• Mammalian thioredoxin reductase as a drug target in anticancer therapy through direct apoptosis induction by selenium compromised forms of the protein

  2006cites this paper
• Characterization of mitochondrial thioredoxin reductase from C. elegans.

  2006cites this paper
• Selenoprotein Synthesis: A Unique Translational Mechanism Used by a Diverse Family of Proteins

  2005cites this paper
• Nematode selenoproteome: the use of the selenocysteine insertion system to decode one codon in an animal genome?

  2005cites this paper
• Selenocysteine in proteins-properties and biotechnological use.

  2005cites this paper
• A selenocysteine tRNA and SECIS element in Plasmodium falciparum.

  2005cites this paper
• Selenium, the thyroid, and the endocrine system.

  2005cites this paper
• Thioredoxin is related to life span regulation and oxidative stress response in Caenorhabditis elegans

  2005cites this paper
• Measurement of Thioredoxin and Thioredoxin Reductase

  2005cites this paper
• An HIV-1 encoded peptide mimics the DNA binding loop of NF-kappaB and binds thioredoxin with high affinity.

  2005cites this paper
• The GRIMs: a new interface between cell death regulation and interferon/retinoid induced growth suppression.

  2004cites this paper
• Identification of trace element-containing proteins in genomic databases.

  2004cites this paper
• A 35 kDa NAD(P)H oxidase previously isolated from the archaeon Sulfolobus solfataricus is instead a thioredoxin reductase.

  2004cites this paper
• Linked thioredoxin-glutathione systems in platyhelminths.

  2004cites this paper
• Non‐animal origin of animal thioredoxin reductases: Implications for selenocysteine evolution and evolution of protein function through carboxy‐terminal extensions

  2003cites this paper
• Alternative mRNAs Arising from Trans-splicing Code for Mitochondrial and Cytosolic Variants of Echinococcus granulosus Thioredoxin Glutathione Reductase*

  2003cites this paper
• Selenium compounds inhibit IκB kinase (IKK) and nuclear factor-κB (NF-κB) in prostate cancer cells

  2002cites this paper
• Recoding: translational bifurcations in gene expression.

  2002cites this paper
• The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase.

  2002cites this paper
• Selenoproteins and selenocysteine insertion system in the model plant cell system, Chlamydomonas reinhardtii

  2002cites this paper
• Selenium compounds inhibit I kappa B kinase (IKK) and nuclear factor-kappa B (NF-kappa B) in prostate cancer cells.

  2002cites this paper
• The thioredoxin system of Plasmodium falciparum and other parasites

  2002cites this paper
• Evolutionarily different RNA motifs and RNA-protein complexes to achieve selenoprotein synthesis.

  2002cites this paper
• Protein factors mediating selenoprotein synthesis.

  2002cites this paper
• Selenium-containing proteins in mammals and other forms of life.

  2002cites this paper
• Mutational Analysis of Human Thioredoxin Reductase 1

  2002cites this paper
• The diversity and evolution of thioredoxin reductase: new perspectives.

  2002cites this paper
• Selenium regulation of thioredoxin reductase activity and mRNA levels in rat liver.

  2001cites this paper
• In silico identification of novel selenoproteins in the Drosophila melanogaster genome

  2001cites this paper
• Selenium metabolism in zebrafish: multiplicity of selenoprotein genes and expression of a protein containing 17 selenocysteine residues

  2000cites this paper
• Identification and Functional Characterization of Thioredoxin from Trypanosoma brucei brucei *

  2000cites this paper
• Substituting Selenocysteine for Catalytic Cysteine 41 Enhances Enzymatic Activity of Plant Phospholipid Hydroperoxide Glutathione Peroxidase Expressed in Escherichia coli *

  2000cites this paper
• Analysis of Selenocysteine‐Containing Proteins

  2000cites this paper
• The class 2 selenophosphate synthetase gene of Drosophila contains a functional mammalian‐type SECIS

  2000cites this paper
• News and views on thioredoxin reductases.

  1999cites this paper
• Redox Regulation of Cell Signaling by Selenocysteine in Mammalian Thioredoxin Reductases*

  1999cites this paper
• The Caenorhabditis elegans Homologue of Thioredoxin Reductase Contains a Selenocysteine Insertion Sequence (SECIS) Element That Differs from Mammalian SECIS Elements but Directs Selenocysteine Incorporation*

  1999cites this paper
• New Mammalian Selenocysteine-containing Proteins Identified with an Algorithm That Searches for Selenocysteine Insertion Sequence Elements*

  1999cites this paper