Identification of J-chain in polymeric immunoglobulins from a variety of species by cross-reaction with rabbit antisera to human J-chain.

Two rabbit antisera, rendered specific for human J chains, were shown to cross-precipitate extensively with J chains of completely reduced and alkylated polymeric immunoglobulins (IgA, IgM, and/or SIgA) from the dog, cat, cow, goat, sheep, pig, horse, hedgehog, guinea pig, rat, mouse, and chicken. The data emphasize the great evolutionary stability of the J polypeptide chain.

• Publication year

  1973

• Venue

  Journal of Immunology

• Publication date

  1973-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.111.5.1590PMID 4200782
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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