Yersinia Type III Secretion System Master Regulator LcrF

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Journal of Bacteriology

• Publication date

  2015-12-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JB.00686-15PMID 26644429PMCID PMC4751813
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• RcsB positively regulates the Yersinia Ysc-Yop type III secretion system by activating expression of the master transcriptional regulator LcrF.

  2015influential reference
• Absence of YbeY RNase compromises the growth and enhances the virulence plasmid gene expression of Yersinia enterocolitica O:3.

  2015cited by this paper
• Transcriptomic Profiling of Yersinia pseudotuberculosis Reveals Reprogramming of the Crp Regulon by Temperature and Uncovers Crp as a Master Regulator of Small RNAs

  2015cited by this paper
• IscR Is Essential for Yersinia pseudotuberculosis Type III Secretion and Virulence

  2014influential reference
• LcrQ Blocks the Role of LcrF in Regulating the Ysc-Yop Type III Secretion Genes in Yersinia pseudotuberculosis

  2014influential reference
• Coordinate Regulation of the Suf and Isc Fe-S Cluster Biogenesis Pathways by IscR Is Essential for Viability of Escherichia coli

  2014cited by this paper
• ExsA and LcrF Recognize Similar Consensus Binding Sites, but Differences in Their Oligomeric State Influence Interactions with Promoter DNA

  2013influential reference
• Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity

  2013cited by this paper
• Translational Regulation of Yersinia enterocolitica mRNA Encoding a Type III Secretion Substrate*

  2013cited by this paper
• Modulation of innate immune responses by Yersinia type III secretion system translocators and effectors

  2013cited by this paper
• Characterization of the [2Fe-2S] cluster of Escherichia coli transcription factor IscR.

  2012cited by this paper
• Elevated CpxR~P levels repress the Ysc-Yop type III secretion system of Yersinia pseudotuberculosis.

  2012cited by this paper
• Concerted Actions of a Thermo-labile Regulator and a Unique Intergenic RNA Thermosensor Control Yersinia Virulence

  2012influential reference
• FIMO: scanning for occurrences of a given motif

  2011cited by this paper
• Expression hierarchy in the Yersinia type III secretion system established through YopD recognition of RNA

  2011cited by this paper
• Intrinsic and Extrinsic Regulation of Type III Secretion Gene Expression in Pseudomonas Aeruginosa

  2011cited by this paper
• The Small RNA Chaperone Hfq Is Required for the Virulence of Yersinia pseudotuberculosis

  2010cited by this paper
• Cell Membrane Is Impaired, Accompanied by Enhanced Type III Secretion System Expression in Yersinia pestis Deficient in RovA Regulator

  2010cited by this paper
• SeaView version 4: A multiplatform graphical user interface for sequence alignment and phylogenetic tree building.

  2010cited by this paper
• AraC protein, regulation of the l-arabinose operon in Escherichia coli, and the light switch mechanism of AraC action.

  2010cited by this paper
• Mechanism of Transcriptional Activation by Pseudomonas aeruginosa ExsA

  2009influential reference
• Transcriptional profiling of a mice plague model: insights into interaction between Yersinia pestis and its host

  2009cited by this paper
• MEME Suite: tools for motif discovery and searching

  2009cited by this paper
• Sequence-specific binding to a subset of IscR-regulated promoters does not require IscR Fe-S cluster ligation.

  2009cited by this paper
• Functional Domains of ExsA, the Transcriptional Activator of the Pseudomonas aeruginosa Type III Secretion System

  2009cited by this paper
• YtxR Acts as an Overriding Transcriptional Off Switch for the Yersinia enterocolitica Ysc-Yop Type 3 Secretion System

  2008influential reference
• Growth of Yersinia pseudotuberculosis in human plasma: impacts on virulence and metabolic gene expression

  2008cited by this paper
• IscR Controls Iron-Dependent Biofilm Formation in Escherichia coli by Regulating Type I Fimbria Expression

  2008cited by this paper
• Characterization of ExsA and of ExsA‐dependent promoters required for expression of the Pseudomonas aeruginosa type III secretion system

  2008cited by this paper
• Association of hemochromatosis with infectious diseases: expanding spectrum.

  2007cited by this paper
• Transcriptome analysis of Yersinia pestis in human plasma: an approach for discovering bacterial genes involved in septicaemic plague.

  2007cited by this paper
• FourU: a novel type of RNA thermometer in Salmonella

  2007cited by this paper
• H-NS Represses inv Transcription in Yersinia enterocolitica through Competition with RovA and Interaction with YmoA

  2006cited by this paper
• Global gene regulation in Yersinia enterocolitica: effect of FliA on the expression levels of flagellar and plasmid-encoded virulence genes

  2006cited by this paper
• IscR‐dependent gene expression links iron‐sulphur cluster assembly to the control of O2‐regulated genes in Escherichia coli

  2006cited by this paper
• IscR acts as an activator in response to oxidative stress for the suf operon encoding Fe‐S assembly proteins

  2006cited by this paper
• Environmental Regulation and Virulence Attributes of the Ysa Type III Secretion System of Yersinia enterocolitica Biovar 1B

  2005cited by this paper
• H-NS is a part of a thermally controlled mechanism for bacterial gene regulation.

  2005cited by this paper
• RovA is autoregulated and antagonizes H‐NS‐mediated silencing of invasin and rovA expression in Yersinia pseudotuberculosis

  2004cited by this paper
• The ATP‐dependent ClpXP and Lon proteases regulate expression of the Yersinia pestis type III secretion system via regulated proteolysis of YmoA, a small histone‐like protein

  2004cited by this paper
• Role of the Hha/YmoA family of proteins in the thermoregulation of the expression of virulence factors.

  2002cited by this paper
• YopD and LcrH Regulate Expression of Yersinia enterocolitica YopQ by a Posttranscriptional Mechanism and Bind to yopQ RNA

  2002cited by this paper
• Yersinia enterocolitica Type III Secretion: yscM1 and yscM2 Regulate yop Gene Expression by a Posttranscriptional Mechanism That Targets the 5′ Untranslated Region of yop mRNA

  2002cited by this paper
• Evidence for Direct Protein-Protein Interaction between Members of the Enterobacterial Hha/YmoA and H-NS Families of Proteins

  2002cited by this paper
• IscR, an Fe-S cluster-containing transcription factor, represses expression of Escherichia coli genes encoding Fe-S cluster assembly proteins

  2001cited by this paper
• Novel Group of Virulence Activators within the AraC Family That Are Not Restricted to Upstream Binding Sites

  2001cited by this paper
• Plague and other human infections caused by Yersinia species.

  2001cited by this paper
• Rns, a virulence regulator within the AraC family, requires binding sites upstream and downstream of its own promoter to function as an activator

  2000cited by this paper
• Yersinia enterocolitica: overview and epidemiologic correlates.

  1999cited by this paper
• The Yersinia enterocolitica pYV Virulence Plasmid Contains Multiple Intrinsic DNA Bends Which Melt at 37°C

  1999cited by this paper
• Yersiniosis I: Microbiological and Clinicoepidemiological Aspects of Plague and Non-Plague Yersinia Infections

  1999cited by this paper
• Yersiniosis II: The Pathogenesis of Yersinia Infections

  1999cited by this paper
• The Virulence Plasmid of Yersinia, an Antihost Genome

  1998cited by this paper
• YopD of Yersinia pestis Plays a Role in Negative Regulation of the Low-Calcium Response in Addition to Its Role in Translocation of Yops

  1998cited by this paper
• A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator.

  1998cited by this paper
• YscM1 and YscM2, two Yersinia enterocolitica proteins causing downregulation of yop transcription

  1997influential reference
• Temperature‐dependent regulation of Yersinia enterocolitica Class III flagellar genes

  1996cited by this paper
• Modulation of Virulence Factor Expression by Pathogen Target Cell Contact

  1996cited by this paper
• A new class of proteins regulating gene expression in enterobacteria

  1994cited by this paper
• Transcriptional organization of the trans-regulatory locus which controls exoenzyme S synthesis in Pseudomonas aeruginosa

  1994cited by this paper
• Identification of DNA sequences recognized by VirF, the transcriptional activator of the Yersinia yop regulon

  1994influential reference
• Thermoregulation in Yersinia enterocolitica is coincident with changes in DNA supercoiling

  1994cited by this paper
• Role of the transcription activator virF and the histone-like protein YmoA in the thermoregulation of virulence functions in yersiniae.

  1993cited by this paper
• Temperature sensing in Yersinia pestis: translation of the LcrF activator protein is thermally regulated

  1993cited by this paper
• LcrF is the temperature-regulated activator of the yadA gene of Yersinia enterocolitica and Yersinia pseudotuberculosis

  1992cited by this paper
• Role of the transcriptional activator, VirF, and temperature in the expression of the pYV plasmid genes of Yersinia enterocolitica

  1992influential reference
• Structure and regulation of the Yersinia pestis yscBCDEF operon

  1992cited by this paper
• Temperature sensing in Yersinia pestis: regulation of yopE transcription by lcrF

  1992cited by this paper
• A novel protein, LcrQ, involved in the low-calcium response of Yersinia pseudotuberculosis shows extensive homology to YopH

  1992cited by this paper
• Analysis of virC, an operon involved in the secretion of Yop proteins by Yersinia enterocolitica

  1991cited by this paper
• ymoA, a Yersinia enterocolitica chromosomal gene modulating the expression of virulence functions

  1991cited by this paper
• The pYV plasmid of Yersinia encodes a lipoprotein, YlpA, related to TraT

  1990cited by this paper
• Homology between virF, the transcriptional activator of the Yersinia virulence regulon, and AraC, the Escherichia coli arabinose operon regulator

  1989cited by this paper
• Nucleotide sequence and transcription analysis of yop51 from Yersinia enterocolitica W22703.

  1988cited by this paper
• Identification and mapping of the temperature-inducible, plasmid-encoded proteins of Yersinia spp

  1988cited by this paper
• Transcription of the yop regulon from Y. enterocolitica requires trans acting pYV and chromosomal genes.

  1987cited by this paper
• Temperature-controlled plasmid regulon associated with low calcium response in Yersinia pestis

  1986cited by this paper
• A low-Ca2+ response operon encodes the V antigen of Yersinia pestis

  1986cited by this paper
• Isolation and characterization of Ca2+-blind mutants of Yersinia pestis

  1985cited by this paper
• Studies on the nutrition and physiology of Pasteurella pestis. III. Effects of calcium ions on the growth of virulent and avirulent strains of Pasteurella pestis.

  1959cited by this paper
• ROLE OF CALCIUM IONS IN THE STIMULATION OF GROWTH OF VIRULENT STRAINS OF PASTEURELLA PESTIS

  1958cited by this paper

• Structural and Biophysical Characterization of the Yersinia Type Three Secretion System ATPase YscN.

  2026cites this paper
• Quorum sensing employs a dual regulatory mechanism to repress T3SS gene expression

  2025cites this paper
• Temperature Adaptive Biofilm Formation in Yersinia enterocolitica in Response to pYV Plasmid and Calcium

  2025cites this paper
• Yersinia actively downregulates type III secretion and adhesion at higher cell densities

  2025cites this paper
• IscR-mediated sensing of iron-sulfur cluster demand coordinates virulence gene expression in Yersinia pseudotuberculosis

  2025cites this paper
• Dynamic interaction of the Yersinia pseudotuberculosis type three secretion system proteins LcrV and LcrG

  2025cites this paper
• Pathogenicity and virulence of Yersinia

  2024cites this paper
• Multidrug resistance in Pseudomonas aeruginosa: genetic control mechanisms and therapeutic advances

  2024cites this paper
• RNase-mediated reprogramming of Yersinia virulence

  2024cites this paper
• Quorum sensing employs a dual regulatory mechanism to repress T3SS gene expression

  2024cites this paper
• YmoA functions as a molecular stress sensor in Yersinia

  2024cites this paper
• Sensing for survival: specialised regulatory mechanisms of Type III secretion systems in Gram‐negative pathogens

  2024cites this paper
• A Marine Bacterium with Animal-Pathogen-Like Type III Secretion Elicits the Nonhost Hypersensitive Response in a Land Plant

  2023cites this paper
• A ParDE toxin–antitoxin system is responsible for the maintenance of the Yersinia virulence plasmid but not for type III secretion-associated growth inhibition

  2023cites this paper
• Calcium-responsive plasmid copy number regulation is dependent on discrete YopD domains in Yersinia pseudotuberculosis.

  2023cites this paper
• Toxin-linked mobile genetic elements in major enteric bacterial pathogens

  2023cites this paper
• The oxidative stress response, in particular the katY gene, is temperature-regulated in Yersinia pseudotuberculosis

  2023cites this paper
• Repression by the H-NS/YmoA histone-like protein complex enables IscR dependent regulation of the Yersinia T3SS

  2022cites this paper
• Cellular functions of the ClpP protease impacting bacterial virulence

  2022influential citation
• RNA thermometer-coordinated assembly of the Yersinia injectisome.

  2022cites this paper
• The Regulatory Circuit Underlying Downregulation of a Type III Secretion System in Yersinia enterocolitica by Transcription Factor OmpR

  2022cites this paper
• Pilotins are mobile T3SS components involved in assembly and substrate specificity of the bacterial type III secretion system

  2022cites this paper
• Role of the Yersinia pseudotuberculosis Virulence Plasmid in Pathogen-Phagocyte Interactions in Mesenteric Lymph Nodes

  2021cites this paper
• Characterization of the binding motif for the T3SS master regulator LcrF in Yersinia pseudotuberculosis.

  2021cites this paper
• An update of the unceasingly growing and diverse AraC/XylS family of transcriptional activators.

  2021cites this paper
• Genome Scale Analysis Reveals IscR Directly and Indirectly Regulates Virulence Factor Genes in Pathogenic Yersinia

  2021cites this paper
• LcrQ Coordinates with the YopD-LcrH Complex To Repress lcrF Expression and Control Type III Secretion by Yersinia pseudotuberculosis

  2021cites this paper
• The Small Protein YmoA Controls the Csr System and Adjusts Expression of Virulence-Relevant Traits of Yersinia pseudotuberculosis

  2021cites this paper
• The transcription factor IscR promotes Yersinia type III secretion system activity by antagonizing the repressive H-NS-YmoA histone-like protein complex

  2021cites this paper
• CpxR regulates the Rcs phosphorelay system in controlling the Ysc-Yop type III secretion system in Yersinia pseudotuberculosis.

  2020cites this paper
• S-nitrosylation-mediated activation of a histidine kinase represses the type 3 secretion system and promotes virulence of an enteric pathogen

  2020cites this paper
• Possible drugs for the treatment of bacterial infections in the future: anti-virulence drugs

  2020cites this paper
• A general view on virulence determinants and infection strategies of Yersinia enterocolitica

  2020cites this paper
• Transcriptional and Post-transcriptional Regulatory Mechanisms Controlling Type III Secretion.

  2019cites this paper
• A Rapid Antimicrobial Susceptibility Test for Determining Yersinia pestis Susceptibility to Doxycycline by RT-PCR Quantification of RNA Markers

  2019cites this paper
• Temperature Control of psaA Expression by PsaE and PsaF in Yersinia pestis

  2019cites this paper
• The Pathogenic Yersiniae – Advances in the Understanding of Physiology and Virulence, Volume II

  2019influential citation
• Iron availability and oxygen tension regulate the Yersinia Ysc type III secretion system to enable disseminated infection

  2019cites this paper
• On the road to structure-based development of anti-virulence therapeutics targeting the type III secretion system injectisome.

  2019cites this paper
• Discovering RNA-Based Regulatory Systems for Yersinia Virulence

  2018cites this paper
• RNA Thermometers in Bacterial Pathogens

  2018cites this paper
• An Experimental Pipeline for Initial Characterization of Bacterial Type III Secretion System Inhibitor Mode of Action Using Enteropathogenic Yersinia

  2018cites this paper
• Type VI Secretion Systems Present New Insights on Pathogenic Yersinia

  2018cites this paper
• RNA‐mediated signal perception in pathogenic bacteria

  2017cites this paper
• Timing and targeting of Type III secretion translocation of virulence effectors in Yersinia

  2017cites this paper
• RNA Regulators: Formidable Modulators of Yersinia Virulence.

  2017cites this paper
• Aurintricarboxylic acid structure modifications lead to reduction of inhibitory properties against virulence factor YopH and higher cytotoxicity

  2016cites this paper