SCFFbxw15 Mediates Histone Acetyltransferase Binding to Origin Recognition Complex (HBO1) Ubiquitin-Proteasomal Degradation to Regulate Cell Proliferation*

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Biological Chemistry

• Publication date

  2013-01-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1074/jbc.M112.426882PMID 23319590PMCID PMC3585065
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1996influential reference
• TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

  1995cited by this paper
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  1992cited by this paper

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