Innovative encapsulation platform based on pancreatic extracellular matrix achieve substantial insulin delivery

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Journal of Controlled Release

• Publication date

  2017-07-10

• Fields of study

  Medicine, Chemistry, Engineering

• Identifiers
  DOI 10.1016/j.jconrel.2016.07.045PMID 27476611
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cell encapsulation: technical and clinical advances.

  2015cited by this paper
• Application of cell encapsulation for controlled delivery of biological therapeutics.

  2014cited by this paper
• Generation of functional human pancreatic β cells in vitro.

  2014cited by this paper
• Clinical application of microencapsulated islets: actual prospectives on progress and challenges.

  2014cited by this paper
• Mesenchymal stem cells: immune evasive, not immune privileged

  2014cited by this paper
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  2014cited by this paper
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  2014cited by this paper
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  2014cited by this paper
• The Temporal and Hierarchical Control of Transcription Factors-Induced Liver to Pancreas Transdifferentiation

  2014cited by this paper
• Intrapatient variations in type 1 diabetes-specific iPS cell differentiation into insulin-producing cells.

  2013cited by this paper
• Extracellular matrix signaling in morphogenesis and repair.

  2013cited by this paper
• Thick Acellular Heart Extracellular Matrix with Inherent Vasculature: A Potential Platform for Myocardial Tissue Regeneration

  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
• Engineering cell platforms for myocardial regeneration

  2011cited by this paper
• Mesenchymal stem cells: mechanisms of inflammation.

  2011cited by this paper
• Understanding the effect of mean pore size on cell activity in collagen-glycosaminoglycan scaffolds

  2010cited by this paper
• Adult cell fate reprogramming: converting liver to pancreas.

  2010cited by this paper
• Encapsulated human mesenchymal stem cells: a unique hypoimmunogenic platform for long‐term cellular therapy

  2010cited by this paper
• Extracellular Matrix in Pancreatic Islets: Relevance to Scaffold Design and Transplantation

  2009cited by this paper
• Alginate-PLL cell encapsulation system Co-entrapping PLGA-microspheres for the continuous release of anti-inflammatory drugs

  2009cited by this paper
• Effect of pore size on ECM secretion and cell growth in gelatin scaffold for articular cartilage tissue engineering.

  2009cited by this paper
• Acellular Cardiac Extracellular Matrix as a Scaffold for Tissue Engineering: In Vitro Cell Support, Remodeling, and Biocompatibility

  2009cited by this paper
• Reestablishment of Microenvironment is Necessary to Maintain In Vitro and In Vivo Human Islet Function

  2008cited by this paper
• Myocardial tissue engineering: a review

  2007cited by this paper
• Human Heart, Spleen, and Perirenal Fat-Derived Mesenchymal Stem Cells Have Immunomodulatory Capacities

  2007cited by this paper
• Regenerative medicine: using liver to generate pancreas for treating diabetes.

  2006cited by this paper
• Small intestinal submucosa improves islet survival and function in vitro culture.

  2006cited by this paper
• Alginate–chitosan complex coacervation for cell encapsulation: Effect on mechanical properties and on long‐term viability

  2006cited by this paper
• Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.

  2006cited by this paper
• Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering

  2005cited by this paper
• Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells

  2005cited by this paper
• Cells, scaffolds, and molecules for myocardial tissue engineering.

  2005cited by this paper
• The effect of pore size on cell adhesion in collagen-GAG scaffolds.

  2005cited by this paper
• Regulation of Human β-Cell Adhesion, Motility, and Insulin Secretion by Collagen IV and Its Receptor α1β1*

  2004cited by this paper
• Regulation of human beta-cell adhesion, motility, and insulin secretion by collagen IV and its receptor alpha1beta1.

  2004cited by this paper
• New organs from our own tissues: liver-to-pancreas transdifferentiation.

  2003cited by this paper
• A novel approach to increase human islet cell mass while preserving beta-cell function.

  2002cited by this paper
• Co-culture of extracellular matrix suppresses the cell death of rat pancreatic islets

  2002cited by this paper
• The in vivo delivery of heterologous proteins by microencapsulated recombinant cells.

  1999cited by this paper
• Growth kinetics, self‐renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation

  1997cited by this paper
• Functional human hepatocytes: isolation from small liver biopsy samples and primary cultivation with liver-specific functions.

  1995cited by this paper
• Method for the Quantification of Alginate in Microcapsules

  1993cited by this paper
• Reference range data base for serum chemistry and hematology values in laboratory animals.

  1986cited by this paper
• Microencapsulated islets as bioartificial endocrine pancreas.

  1980cited by this paper

• State of the Art of Bioengineering Approaches in Beta-Cell Replacement

  2025cites this paper
• Comprehensive biocompatibility profiling of human pancreas-derived biomaterial

  2025cites this paper
• Developments in gastrointestinal organoid cultures to recapitulate tissue environments

  2025cites this paper
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• Rat Islet pECM Hydrogel-Based Microencapsulation: A Protective Niche for Xenotransplantation

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• Synergistic strategies in tissue engineering: The role of exosomes and decellularized extracellular matrix hydrogels.

  2025cites this paper
• Designing drug delivery systems for cell therapy

  2024cites this paper
• Traditional and emerging strategies using hepatocytes for pancreatic regenerative medicine

  2024cites this paper
• Decellularization and Their Significance for Tissue Regeneration in the Era of 3D Bioprinting

  2024cites this paper
• The Role of the Pancreatic Extracellular Matrix as a Tissue Engineering Support for the Bioartificial Pancreas

  2024cites this paper
• Which detergent is most suitable for the generation of an acellular pancreas bioscaffold?

  2024cites this paper
• ECM-based bioactive microencapsulation significantly improves islet function and graft performance.

  2023cites this paper
• Enhancing longevity of immunoisolated pancreatic islet grafts by modifying both the intracapsular and extracapsular environment.

  2023cites this paper
• Development potential of extracellular matrix hydrogels as hemostatic materials

  2023cites this paper
• Investigation of the effect of pancreatic decellularized matrix on encapsulated Islets of Langerhans with mesenchymal stem cells.

  2023cites this paper
• The molecular mechanisms of extracellular matrix-derived hydrogel therapy in idiopathic pulmonary fibrosis models.

  2023cites this paper
• Decellularized Wharton's jelly scaffold enhances differentiation of mesenchymal stem cells to insulin-secreting cells.

  2022cites this paper
• Bioengineering the Vascularized Endocrine Pancreas: A Fine-Tuned Interplay Between Vascularization, Extracellular-Matrix-Based Scaffold Architecture, and Insulin-Producing Cells

  2022cites this paper
• Development of a bioactive microencapsulation platform incorporating decellularized extracellular matrix to entrap human induced pluripotent stem cells for versatile biomedical applications

  2022cites this paper
• A human pancreatic ECM hydrogel optimized for 3-D modeling of the islet microenvironment

  2022cites this paper
• Core-shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine.

  2022cites this paper
• Controlled Release of Insulin Based on Temperature and Glucose Dual Responsive Biomicrocapsules

  2022cites this paper
• [Generating pancreatic islets organoids: Langerhanoids].

  2022cites this paper
• Fabrication of bioartificial pancreas using decellularized rat testicular tissue.

  2022cites this paper
• Encapsulation of stem-cell derived β-cells: A promising approach for the treatment for type 1 diabetes mellitus.

  2022cites this paper
• Tissue engineering of decellularized pancreas scaffolds for regenerative medicine in diabetes.

  2022cites this paper
• Preparation and Use of Decellularized Extracellular Matrix for Tissue Engineering

  2022cites this paper
• Spleen extracellular matrix provides a supportive microenvironment for β-cell function

  2022cites this paper
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  2021cites this paper
• Proteomic and Bioinformatic Analysis of Decellularized Pancreatic Extracellular Matrices

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• Extracellular Matrix Hydrogels Originated from Different Organs Mediate Tissue-Specific Properties and Function

  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
• Co-encapsulation of ECM proteins to enhance pancreatic islet cell function

  2020cites this paper
• [Research progress of decellularized extracellular matrix hydrogel in regenerative medicine].

  2020cites this paper
• BoneMA – Synthesis and Characterization of a Methacrylated Bone-derived Hydrogel for Bioprinting of Vascularized Tissues

  2020cites this paper
• Porcine arterial ECM hydrogel: Designing an in vitro angiogenesis model for long‐term high‐throughput research

  2020cites this paper
• Pancreatic Extracellular Matrix and Platelet-rich Plasma Constructing Injectable Hydrogel For Pancreas Tissue Engineering.

  2020cites this paper
• Decellularised scaffolds: just a framework? Current knowledge and future directions

  2020cites this paper
• Decellularization Systems and Devices: State-of-the-art Review.

  2020cites this paper
• Decellularized Extracellular Matrix-based Bioinks for Engineering Tissue- and Organ-specific Microenvironments.

  2020cites this paper
• Interpenetrating Network of Alginate-Human Adipose Extracellular Matrix Hydrogel for Islet Cells Encapsulation.

  2020cites this paper
• Applications of decellularized materials in tissue engineering: advantages, drawbacks and current improvements, and future perspectives.

  2020cites this paper
• BoneMA—synthesis and characterization of a methacrylated bone-derived hydrogel for bioprinting of in-vitro vascularized tissue constructs

  2020cites this paper
• Stem Cell-Derived Insulin-Producing Cells in 3D Engineered Tissue in a Perfusion Flow Bioreactor

  2020cites this paper
• Processed Tissues

  2020cites this paper
• Engineering Strategies to Improve Islet Transplantation for Type 1 Diabetes Therapy.

  2019cites this paper
• Proteomic analysis of decellularized pancreatic matrix identifies collagen V as a critical regulator for islet organogenesis from human pluripotent stem cells.

  2019cites this paper
• The emerging field of pancreatic tissue engineering: A systematic review and evidence map of scaffold materials and scaffolding techniques for insulin-secreting cells

  2019cites this paper
• New Approach to Measuring Oxygen Diffusion and Consumption in Encapsulated Living Cells, based on Electron Spin Resonance Microscopy.

  2019cites this paper
• The impact of decellularization methods on extracellular matrix derived hydrogels

  2019cites this paper
• Extracellular matrix-based hydrogels obtained from human tissues: a work still in progress.

  2019cites this paper
• Liver to Pancreas Transdifferentiation

  2019cites this paper
• Scaffolds for pancreatic tissue engineering

  2019cites this paper
• Processed Tissue–Derived Extracellular Matrices: Tailored Platforms Empowering Diverse Therapeutic Applications

  2019cites this paper
• Adipose tissue-derived ECM hydrogels and their use as 3 D culture scaffold

  2019cites this paper
• Adipose tissue-derived ECM hydrogels and their use as 3D culture scaffold

  2019cites this paper
• Generation of Human Stem Cell-Derived Pancreatic Organoids (POs) for Regenerative Medicine.

  2019cites this paper
• A Review of Decellularized Extracellular Matrix Biomaterials for Regenerative Engineering Applications

  2019cites this paper
• 3D cell printing of islet-laden pancreatic tissue-derived extracellular matrix bioink constructs for enhancing pancreatic functions.

  2019cites this paper
• Strategies for controlling egress of therapeutic cells from hydrogel microcapsules

  2019cites this paper
• Paving the way for successful islet encapsulation.

  2019cites this paper
• Nanotechnology in cell replacement therapies for type 1 diabetes.

  2019cites this paper
• 3-D physiomimetic extracellular matrix hydrogels provide a supportive microenvironment for rodent and human islet culture.

  2019cites this paper
• Towards the development of a bioartificial pancreas for transplantation

  2018cites this paper
• Report of the Key Opinion Leaders Meeting on Stem Cell-derived Beta Cells.

  2018cites this paper
• Evaluation of Different Decellularization Protocols on the Generation of Pancreas-Derived Hydrogels

  2018cites this paper
• Organ-Derived Decellularized Extracellular Matrix: A Game Changer for Bioink Manufacturing?

  2018cites this paper
• Rebuilding a better home for transplanted islets

  2018cites this paper
• Pancreatic extracellular communication. Applications to beta cell cultures and islet amyloid polypeptide aggregation

  2018cites this paper
• 3D-Models of Insulin-Producing β-Cells: from Primary Islet Cells to Stem Cell-Derived Islets

  2017cites this paper
• Selection of Implantation Sites for Transplantation of Encapsulated Pancreatic Islets

  2017cites this paper
• Restoring the biophysical properties of decellularized patches through recellularization.

  2017cites this paper
• Extracellular matrix hydrogel therapies: In vivo applications and development.

  2017influential citation
• Saldin, Lindsey T. and Cramer, Madeline C and Velankar, Sachin S and White, Lisa J. and Badylak,

  2017cites this paper
• Cold-perfusion decellularization of whole-organ porcine pancreas supports human fetal pancreatic cell attachment and expression of endocrine and exocrine markers

  2017cites this paper
• Biodegradable Scaffolds for Bone Regeneration Combined with Drug-Delivery Systems in Osteomyelitis Therapy

  2017cites this paper
• Engineering human renal epithelial cells for transplantation in regenerative medicine.

  2017cites this paper
• Potential differentiation of islet-like cells from pregnant cow-derived placental stem cells.

  2017cites this paper
• Electrospun Extracellular Matrix: Paving the Way to Tailor‐Made Natural Scaffolds for Cardiac Tissue Regeneration

  2017cites this paper
• Biohybrid cardiac ECM-based hydrogels improve long term cardiac function post myocardial infarction.

  2017cites this paper
• Extracellular matrix hydrogels from decellularized tissues: Structure and function.

  2017cites this paper
• 2.24 Hydrogels of Decellularized Matrix

  2017cites this paper
• 3D Bioprinting of Micro-Porous Macro Encapsulation System for Pancreatic Islet Transplantation

  year unknowncites this paper