Eicosapentaenoic acid attenuates obesity-related hepatocellular carcinogenesis

Akane Inoue-Yamauchi,H. Itagaki,H. Oda

Published 2017 in Carcinogenesis

ABSTRACT

By using a carcinogen-injected dietary obesity model, we demonstrated that eicosapentaenoic acid attenuated the development of hepatocellular carcinoma associated with obesity by inhibiting the activation of STAT3 and subsequent tumor cell proliferation without affecting hepatic inflammation.

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