Expression of alpha-synuclein in the human brain: relation to Lewy body disease.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Brain Research. Molecular Brain Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 11483242
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cortical Lewy body-containing neurons are pyramidal cells: laser confocal imaging of double-immunolabeled sections with anti-ubiquitin and SMI32

  2004cited by this paper
• Synucleinopathies: clinical and pathological implications.

  2001cited by this paper
• Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders.

  2000cited by this paper
• Expression of alpha-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: genes associated with familial Parkinson's disease.

  2000cited by this paper
• Involvement of alpha-synuclein in Parkinson's disease and other neurodegenerative disorders.

  2000cited by this paper
• Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies.

  2000cited by this paper
• Dementia with Lewy bodies: prevalence, clinical spectrum and natural history.

  2000cited by this paper
• Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies.

  2000cited by this paper
• Neuropathology of synuclein aggregates

  2000cited by this paper
• Widespread alterations of alpha-synuclein in multiple system atrophy.

  1999cited by this paper
• Neural expression profile of alpha-synuclein in developing human cortex.

  1999cited by this paper
• Reduced expression of the G209A alpha-synuclein allele in familial Parkinsonism.

  1999cited by this paper
• Increased Expression of Rat Synuclein in the Substantia Nigra Pars Compacta Identified by mRNA Differential Display in a Model of Developmental Target Injury

  1999cited by this paper
• Developmental expression of alpha-synuclein in rat hippocampus and cerebral cortex.

  1999cited by this paper
• Epidemiologic approaches to the study of Parkinson's disease etiology.

  1999cited by this paper
• Mutant and Wild Type Human α-Synucleins Assemble into Elongated Filaments with Distinct Morphologies in Vitro *

  1999cited by this paper
• Both Familial Parkinson’s Disease Mutations Accelerate α-Synuclein Aggregation*

  1999cited by this paper
• Alpha-synuclein expression in substantia nigra and cortex in Parkinson's disease.

  1999cited by this paper
• The expression of alpha-, beta-, and gamma-synucleins in olfactory mucosa from patients with and without neurodegenerative diseases.

  1999cited by this paper
• alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies.

  1998cited by this paper
• Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy.

  1998cited by this paper
• Genetic classification of primary neurodegenerative disease.

  1998cited by this paper
• Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein

  1998cited by this paper
• Protein Nitration in Parkinson's Disease

  1998cited by this paper
• Binding of α-Synuclein to Brain Vesicles Is Abolished by Familial Parkinson’s Disease Mutation*

  1998cited by this paper
• Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development.

  1998cited by this paper
• Oxidative mechanisms in nigral cell death in Parkinson's disease.

  1998cited by this paper
• Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson disease

  1998cited by this paper
• NACP/alpha-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy.

  1998cited by this paper
• Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease.

  1998cited by this paper
• Oxidative Damage to Proteins, Lipids, and DNA in Cortical Brain Regions from Patients with Dementia with Lewy Bodies

  1998cited by this paper
• Mutation in the alpha-synuclein gene and sporadic Parkinson's disease, Alzheimer's disease, and dementia with lewy bodies.

  1998cited by this paper
• Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of α‐synuclein protein implicated in Parkinson's disease

  1998cited by this paper
• Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

  1998cited by this paper
• Alpha synuclein is present in Lewy bodies in sporadic Parkinson's disease

  1998cited by this paper
• Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.

  1997cited by this paper
• Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB)

  1996cited by this paper
• Identification of two distinct synucleins from human brain

  1994cited by this paper
• Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.

  1993cited by this paper
• Neuropeptide Y and catecholamine synthesizing enzymes and their mRNAs in rat sympathetic neurons and adrenal glands: studies on expression, synthesis and axonal transport after pharmacological and experimental manipulations using hybridization techniques and radioimmunoassay.

  1991cited by this paper
• The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

  1991cited by this paper
• The new stereological tools: Disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis

  1988cited by this paper

• Ykt6 SNARE protein drives GluA1 insertion at synaptic spines during LTP

  2025cites this paper
• Exploring the putative role of kallikrein‐6, calpain‐1 and cathepsin‐D in the proteolytic degradation of α‐synuclein in multiple system atrophy

  2018cites this paper
• Endothelin‐converting enzymes degrade α‐synuclein and are reduced in dementia with Lewy bodies

  2017cites this paper
• DNA methylation changes at SNCA intron 1 in patients with dementia with Lewy bodies

  2017cites this paper
• Alpha‐synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL

  2017cites this paper
• Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease

  2016cites this paper
• Parkinson’s disease psychosis as a serotonin-dopamine imbalance syndrome

  2016cites this paper
• Flies with Parkinson's disease.

  2015cites this paper
• The Role of Calcium in Alpha-Synuclein Aggregation : A Potential Mechanism of Neurodegeneration

  2015cites this paper
• Accumulation of α-synuclein in dementia with Lewy bodies is associated with decline in the α-synuclein-degrading enzymes kallikrein-6 and calpain-1

  2014cites this paper
• Synaptic dysfunction in synucleinopathies.

  2013cites this paper
• α-synuclein phosphorylation and truncation are normal events in the adult human brain.

  2012cites this paper
• Neuropathology of sporadic Parkinson disease before the appearance of parkinsonism: preclinical Parkinson disease

  2011cites this paper
• Cleavage of normal and pathological forms of alpha-synuclein by neurosin in vitro.

  2008cites this paper
• Multiplication of the α-synuclein gene is not a common disease mechanism in Lewy body disease

  2007cites this paper
• Selective alterations of gene expression in mice induced by MPTP

  2005cites this paper
• Differential expression of α‐synuclein isoforms in dementia with Lewy bodies

  2004cites this paper
• Glutathione S-transferase 8-8 expression is lower in alcohol-preferring than in alcohol-nonpreferring rats.

  2004cites this paper
• Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease.

  2004cites this paper
• Multiplication of the alpha-synuclein gene is not a common disease mechanism in Lewy body disease.

  2004cites this paper
• Alteration in alpha-synuclein mRNA expression in Parkinson's disease.

  2004cites this paper
• α-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats

  2003cites this paper
• Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies.

  2003cites this paper
• Use of gDNA as internal standard for gene expression in staphylococci in vitro and in vivo.

  2002cites this paper
• Amyloid Precursor Protein, Presenilins, and α-Synuclein: Molecular Pathogenesis and Pharmacological Applications in Alzheimer's Disease

  2002cites this paper